Comparative structural analysis of fruit and stem bromelain from Ananas comosus

Cysteine proteases in pineapple (Ananas comosus) plants are phytotherapeutical agents that demonstrate anti-edematous, anti-inflammatory, anti-thrombotic and fibrinolytic activities. Bromelain has been identified as an active component and as a major protease of A. comosus. Bromelain has gained wide...

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Main Authors:	Ramli, Aizi Nor Mazila, Abdul Manas, Nor Hasmaliana, Abdul Hamid, Azzmer Azzar, Abd. Hamid, Hazrulrizawati, Md. Illias, Rosli
Format:	Article
Language:	English English English
Published:	Elsevier Ireland Ltd 2018
Subjects:	TP248.13 Biotechnology TX341 Nutrition. Foods and food supply
Online Access:	http://irep.iium.edu.my/53935/ http://irep.iium.edu.my/53935/ http://irep.iium.edu.my/53935/ http://irep.iium.edu.my/53935/1/53935_Comparative%20structural%20analysis.pdf http://irep.iium.edu.my/53935/2/53935_Comparative%20structural%20analysis_SCOPUS.pdf http://irep.iium.edu.my/53935/13/53935_Comparative%20structural%20analysis%20of%20fruit%20and%20stem%20bromelain%20from%20Ananas%20comosus_WoS.pdf

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recordtype	eprints
spelling	iium-539352018-10-18T01:53:21Z http://irep.iium.edu.my/53935/ Comparative structural analysis of fruit and stem bromelain from Ananas comosus Ramli, Aizi Nor Mazila Abdul Manas, Nor Hasmaliana Abdul Hamid, Azzmer Azzar Abd. Hamid, Hazrulrizawati Md. Illias, Rosli TP248.13 Biotechnology TX341 Nutrition. Foods and food supply Cysteine proteases in pineapple (Ananas comosus) plants are phytotherapeutical agents that demonstrate anti-edematous, anti-inflammatory, anti-thrombotic and fibrinolytic activities. Bromelain has been identified as an active component and as a major protease of A. comosus. Bromelain has gained wide acceptance and compliance as a phytotherapeutical drug. The proteolytic fraction of pineapple stem is termed stem bromelain, while the one presents in the fruit is known as fruit bromelain. The amino acid sequence and domain analysis of the fruit and stem bromelains demonstrated several differences and similarities of these cysteine protease family members. In addition, analysis of the modelled fruit (BAA21848) and stem (CAA08861) bromelains revealed the presence of unique properties of the predicted structures. Sequence analysis and structural prediction of stem and fruit bromelains of A. comosus along with the comparison of both structures provides a new insight on their distinct properties for industrial application. Elsevier Ireland Ltd 2018-11-15 Article PeerReviewed application/pdf en http://irep.iium.edu.my/53935/1/53935_Comparative%20structural%20analysis.pdf application/pdf en http://irep.iium.edu.my/53935/2/53935_Comparative%20structural%20analysis_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/53935/13/53935_Comparative%20structural%20analysis%20of%20fruit%20and%20stem%20bromelain%20from%20Ananas%20comosus_WoS.pdf Ramli, Aizi Nor Mazila and Abdul Manas, Nor Hasmaliana and Abdul Hamid, Azzmer Azzar and Abd. Hamid, Hazrulrizawati and Md. Illias, Rosli (2018) Comparative structural analysis of fruit and stem bromelain from Ananas comosus. Food Chemistry, 566. pp. 183-191. ISSN 0308-8146 https://www.sciencedirect.com/science/article/pii/S030881461830949X j.foodchem.2018.05.125
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	TP248.13 Biotechnology TX341 Nutrition. Foods and food supply
spellingShingle	TP248.13 Biotechnology TX341 Nutrition. Foods and food supply Ramli, Aizi Nor Mazila Abdul Manas, Nor Hasmaliana Abdul Hamid, Azzmer Azzar Abd. Hamid, Hazrulrizawati Md. Illias, Rosli Comparative structural analysis of fruit and stem bromelain from Ananas comosus
description	Cysteine proteases in pineapple (Ananas comosus) plants are phytotherapeutical agents that demonstrate anti-edematous, anti-inflammatory, anti-thrombotic and fibrinolytic activities. Bromelain has been identified as an active component and as a major protease of A. comosus. Bromelain has gained wide acceptance and compliance as a phytotherapeutical drug. The proteolytic fraction of pineapple stem is termed stem bromelain, while the one presents in the fruit is known as fruit bromelain. The amino acid sequence and domain analysis of the fruit and stem bromelains demonstrated several differences and similarities of these cysteine protease family members. In addition, analysis of the modelled fruit (BAA21848) and stem (CAA08861) bromelains revealed the presence of unique properties of the predicted structures. Sequence analysis and structural prediction of stem and fruit bromelains of A. comosus along with the comparison of both structures provides a new insight on their distinct properties for industrial application.
format	Article
author	Ramli, Aizi Nor Mazila Abdul Manas, Nor Hasmaliana Abdul Hamid, Azzmer Azzar Abd. Hamid, Hazrulrizawati Md. Illias, Rosli
author_facet	Ramli, Aizi Nor Mazila Abdul Manas, Nor Hasmaliana Abdul Hamid, Azzmer Azzar Abd. Hamid, Hazrulrizawati Md. Illias, Rosli
author_sort	Ramli, Aizi Nor Mazila
title	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_short	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_full	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_fullStr	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_full_unstemmed	Comparative structural analysis of fruit and stem bromelain from Ananas comosus
title_sort	comparative structural analysis of fruit and stem bromelain from ananas comosus
publisher	Elsevier Ireland Ltd
publishDate	2018
url	http://irep.iium.edu.my/53935/ http://irep.iium.edu.my/53935/ http://irep.iium.edu.my/53935/ http://irep.iium.edu.my/53935/1/53935_Comparative%20structural%20analysis.pdf http://irep.iium.edu.my/53935/2/53935_Comparative%20structural%20analysis_SCOPUS.pdf http://irep.iium.edu.my/53935/13/53935_Comparative%20structural%20analysis%20of%20fruit%20and%20stem%20bromelain%20from%20Ananas%20comosus_WoS.pdf
first_indexed	2023-09-18T21:16:18Z
last_indexed	2023-09-18T21:16:18Z
_version_	1777411584920911872

Comparative structural analysis of fruit and stem bromelain from Ananas comosus

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