Synthesis and characterization of spermidine containing sulphur

Studies in compound containing sulphur and the polyamine transport system is beneficial in oncology as both affect cancer cells. Compounds containing sulphur such as organosulphur are known for their anti-cancer properties. The polyamine transport system however is known for its ability to interact...

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Main Authors:	Sahabudin, Adzly Hairee, How, Fiona Ni Foong, Abdul Ghani, Radiah
Format:	Conference or Workshop Item
Language:	English
Published:	Penerbit UMT, Universiti Malaysia Terengganu (UMT) 2016
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/53900/ http://irep.iium.edu.my/53900/ http://irep.iium.edu.my/53900/1/53900_Synthesize%20and%20Characterization%20of%20Spermidine.pdf

id	iium-53900
recordtype	eprints
spelling	iium-539002017-05-17T06:26:52Z http://irep.iium.edu.my/53900/ Synthesis and characterization of spermidine containing sulphur Sahabudin, Adzly Hairee How, Fiona Ni Foong Abdul Ghani, Radiah QD Chemistry Studies in compound containing sulphur and the polyamine transport system is beneficial in oncology as both affect cancer cells. Compounds containing sulphur such as organosulphur are known for their anti-cancer properties. The polyamine transport system however is known for its ability to interact with cancer cells directly. By adding sulphur to known natural polyamine, the resulting compound is anticipated to retain both properties. One of the widely used of polyamine moiety is used as the cell delivery vector to transport sulphur to the targeted cancer cells. In this study, the spermidine containing sulphur was synthesized by adding carbon disulphide atoms to spermidine atom. The compound was then characterized and analyzed to determine its physiochemical properties and chemical structure. Determination on the characteristic and chemical structure of the compounds were carried out using various techniques such Fourier transformed infrared spectroscopy, thin layer chromatography and gas chromatography mass spectroscopy. Penerbit UMT, Universiti Malaysia Terengganu (UMT) 2016-11-31 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/53900/1/53900_Synthesize%20and%20Characterization%20of%20Spermidine.pdf Sahabudin, Adzly Hairee and How, Fiona Ni Foong and Abdul Ghani, Radiah (2016) Synthesis and characterization of spermidine containing sulphur. In: 13th Universiti Malaysia Terengganu International Annual Symposium on Sustainability Science and Management (UMTAS 2016), 13th-15th Dec. 2016, Kuala Terengganu. http://umtas2016.umt.edu.my/?page_id=210
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Sahabudin, Adzly Hairee How, Fiona Ni Foong Abdul Ghani, Radiah Synthesis and characterization of spermidine containing sulphur
description	Studies in compound containing sulphur and the polyamine transport system is beneficial in oncology as both affect cancer cells. Compounds containing sulphur such as organosulphur are known for their anti-cancer properties. The polyamine transport system however is known for its ability to interact with cancer cells directly. By adding sulphur to known natural polyamine, the resulting compound is anticipated to retain both properties. One of the widely used of polyamine moiety is used as the cell delivery vector to transport sulphur to the targeted cancer cells. In this study, the spermidine containing sulphur was synthesized by adding carbon disulphide atoms to spermidine atom. The compound was then characterized and analyzed to determine its physiochemical properties and chemical structure. Determination on the characteristic and chemical structure of the compounds were carried out using various techniques such Fourier transformed infrared spectroscopy, thin layer chromatography and gas chromatography mass spectroscopy.
format	Conference or Workshop Item
author	Sahabudin, Adzly Hairee How, Fiona Ni Foong Abdul Ghani, Radiah
author_facet	Sahabudin, Adzly Hairee How, Fiona Ni Foong Abdul Ghani, Radiah
author_sort	Sahabudin, Adzly Hairee
title	Synthesis and characterization of spermidine containing sulphur
title_short	Synthesis and characterization of spermidine containing sulphur
title_full	Synthesis and characterization of spermidine containing sulphur
title_fullStr	Synthesis and characterization of spermidine containing sulphur
title_full_unstemmed	Synthesis and characterization of spermidine containing sulphur
title_sort	synthesis and characterization of spermidine containing sulphur
publisher	Penerbit UMT, Universiti Malaysia Terengganu (UMT)
publishDate	2016
url	http://irep.iium.edu.my/53900/ http://irep.iium.edu.my/53900/ http://irep.iium.edu.my/53900/1/53900_Synthesize%20and%20Characterization%20of%20Spermidine.pdf
first_indexed	2023-09-18T21:16:14Z
last_indexed	2023-09-18T21:16:14Z
_version_	1777411581154426880

Synthesis and characterization of spermidine containing sulphur

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