Optimisation of honey-based hydrogel formulations using response surface modeling

Response surface modeling (RSM) is used by scientists to relate the factors and response variables by using a design matrix that eventually produce optimal formulations. Hence, the objective of this paper is to optimize the honey-based hydrogel formulations by using RSM. From the two level factorial...

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Main Authors: Ab. Hadi, Hazrina, Abdul Jalil, Mohd Azri, Awadh, Ammar Ihsan JawaD
Format: Conference or Workshop Item
Language:English
English
English
Published: 2016
Subjects:
Online Access:http://irep.iium.edu.my/53548/
http://irep.iium.edu.my/53548/1/Cover%20page.pdf
http://irep.iium.edu.my/53548/2/Programme%20book.pdf
http://irep.iium.edu.my/53548/3/RCSTSS%20poster%20updated.pdf
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recordtype eprints
spelling iium-535482016-12-19T03:48:56Z http://irep.iium.edu.my/53548/ Optimisation of honey-based hydrogel formulations using response surface modeling Ab. Hadi, Hazrina Abdul Jalil, Mohd Azri Awadh, Ammar Ihsan JawaD RS Pharmacy and materia medica Response surface modeling (RSM) is used by scientists to relate the factors and response variables by using a design matrix that eventually produce optimal formulations. Hence, the objective of this paper is to optimize the honey-based hydrogel formulations by using RSM. From the two level factorial design result, the optimization test were conducted by using central composite design (CCD) from design experiment software version 8 (DOE 8, Minnesota, USA) to obtain the optimized formulation and control formulation. For hydrogel mixture, polyvinyl alcohol (PVA) and polyethylene glycol (PEG) were used. From the formulation lists, three response (swelling ratio, water vapor transmission and gel fraction) were chosen to study the influence of the factors selected towards the formulations. For the swelling ratio response, only honey concentration shows a significant. Honey concentration and number of cycles showed a significant effect towards the response on water vapor transmission rate. Honey concentration has the most significant effect on the gel fraction percentage. As a conclusion, from this optimization test, the formulation with honey and minimal number of cycles show a good reaction towards the selected response. 2016 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/53548/1/Cover%20page.pdf application/pdf en http://irep.iium.edu.my/53548/2/Programme%20book.pdf application/pdf en http://irep.iium.edu.my/53548/3/RCSTSS%20poster%20updated.pdf Ab. Hadi, Hazrina and Abdul Jalil, Mohd Azri and Awadh, Ammar Ihsan JawaD (2016) Optimisation of honey-based hydrogel formulations using response surface modeling. In: Regional Conference On Science, Technology & Social Sciences, 4th - 6th December 2016, Cameron Highlands, Pahang. (Unpublished)
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Ab. Hadi, Hazrina
Abdul Jalil, Mohd Azri
Awadh, Ammar Ihsan JawaD
Optimisation of honey-based hydrogel formulations using response surface modeling
description Response surface modeling (RSM) is used by scientists to relate the factors and response variables by using a design matrix that eventually produce optimal formulations. Hence, the objective of this paper is to optimize the honey-based hydrogel formulations by using RSM. From the two level factorial design result, the optimization test were conducted by using central composite design (CCD) from design experiment software version 8 (DOE 8, Minnesota, USA) to obtain the optimized formulation and control formulation. For hydrogel mixture, polyvinyl alcohol (PVA) and polyethylene glycol (PEG) were used. From the formulation lists, three response (swelling ratio, water vapor transmission and gel fraction) were chosen to study the influence of the factors selected towards the formulations. For the swelling ratio response, only honey concentration shows a significant. Honey concentration and number of cycles showed a significant effect towards the response on water vapor transmission rate. Honey concentration has the most significant effect on the gel fraction percentage. As a conclusion, from this optimization test, the formulation with honey and minimal number of cycles show a good reaction towards the selected response.
format Conference or Workshop Item
author Ab. Hadi, Hazrina
Abdul Jalil, Mohd Azri
Awadh, Ammar Ihsan JawaD
author_facet Ab. Hadi, Hazrina
Abdul Jalil, Mohd Azri
Awadh, Ammar Ihsan JawaD
author_sort Ab. Hadi, Hazrina
title Optimisation of honey-based hydrogel formulations using response surface modeling
title_short Optimisation of honey-based hydrogel formulations using response surface modeling
title_full Optimisation of honey-based hydrogel formulations using response surface modeling
title_fullStr Optimisation of honey-based hydrogel formulations using response surface modeling
title_full_unstemmed Optimisation of honey-based hydrogel formulations using response surface modeling
title_sort optimisation of honey-based hydrogel formulations using response surface modeling
publishDate 2016
url http://irep.iium.edu.my/53548/
http://irep.iium.edu.my/53548/1/Cover%20page.pdf
http://irep.iium.edu.my/53548/2/Programme%20book.pdf
http://irep.iium.edu.my/53548/3/RCSTSS%20poster%20updated.pdf
first_indexed 2023-09-18T21:15:44Z
last_indexed 2023-09-18T21:15:44Z
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