α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar

The present study was designed to investigate the effect of Ipomoea aquatica extracted using water and methanol at various concentrations on the total phenolics, antioxidant capacity, and a-glucosidase inhibitory activities. Three I. aquatica cultivars were used in this study including the upland ty...

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Main Authors:	Lawal, Umar, Leong, Sze Wei, Shaari, Khozirah, Ismail, Intan Safinar, Khatib, Alfi, Abas, Faridah
Format:	Article
Language:	English
Published:	2016
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/53526/ http://irep.iium.edu.my/53526/ http://irep.iium.edu.my/53526/1/lawal2016%281%29.pdf

id	iium-53526
recordtype	eprints
spelling	iium-535262016-12-13T10:21:02Z http://irep.iium.edu.my/53526/ α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar Lawal, Umar Leong, Sze Wei Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah QD Chemistry The present study was designed to investigate the effect of Ipomoea aquatica extracted using water and methanol at various concentrations on the total phenolics, antioxidant capacity, and a-glucosidase inhibitory activities. Three I. aquatica cultivars were used in this study including the upland type with narrow leaves (K-11), low-land aquatic types with broader shaped leaves (K-25), and bamboo-shaped leaves (K-88). The results revealed that 70% methanol extract of K-11 showed higher total phenolic content and a-glucosidase inhibitory and antioxidant activities than the other two cultivars. The phytochemical constituents in the active extract K-11 were analyzed by means of liquid chromatography coupled with diode array detection and electrospray tandem mass spectroscopy. Eighteen compounds were detected of which 13 were tentatively identiﬁed as quercetin-3-O-sophoroside, quercetin-3-O-glucoside, quercetin-3,7-di-O-glucoside, nomilinic acid glucoside, 4,5-di-O-caffeoylquinic acid, 3,5-di-O-caffeoylquinic acid, luteolin-7-glucoside and 3,4,5-tricaffeolquinic acid, fatty acid together with quercetin, and tricaffeoylquinic acid derivatives. 2016-06-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/53526/1/lawal2016%281%29.pdf Lawal, Umar and Leong, Sze Wei and Shaari, Khozirah and Ismail, Intan Safinar and Khatib, Alfi and Abas, Faridah (2016) α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar. Journal of Food Biochemistry. pp. 1-8. ISSN 1745-4514 (In Press) 10.1111/jfbc.12303
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Lawal, Umar Leong, Sze Wei Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar
description	The present study was designed to investigate the effect of Ipomoea aquatica extracted using water and methanol at various concentrations on the total phenolics, antioxidant capacity, and a-glucosidase inhibitory activities. Three I. aquatica cultivars were used in this study including the upland type with narrow leaves (K-11), low-land aquatic types with broader shaped leaves (K-25), and bamboo-shaped leaves (K-88). The results revealed that 70% methanol extract of K-11 showed higher total phenolic content and a-glucosidase inhibitory and antioxidant activities than the other two cultivars. The phytochemical constituents in the active extract K-11 were analyzed by means of liquid chromatography coupled with diode array detection and electrospray tandem mass spectroscopy. Eighteen compounds were detected of which 13 were tentatively identiﬁed as quercetin-3-O-sophoroside, quercetin-3-O-glucoside, quercetin-3,7-di-O-glucoside, nomilinic acid glucoside, 4,5-di-O-caffeoylquinic acid, 3,5-di-O-caffeoylquinic acid, luteolin-7-glucoside and 3,4,5-tricaffeolquinic acid, fatty acid together with quercetin, and tricaffeoylquinic acid derivatives.
format	Article
author	Lawal, Umar Leong, Sze Wei Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah
author_facet	Lawal, Umar Leong, Sze Wei Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah
author_sort	Lawal, Umar
title	α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar
title_short	α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar
title_full	α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar
title_fullStr	α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar
title_full_unstemmed	α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar
title_sort	α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar
publishDate	2016
url	http://irep.iium.edu.my/53526/ http://irep.iium.edu.my/53526/ http://irep.iium.edu.my/53526/1/lawal2016%281%29.pdf
first_indexed	2023-09-18T21:15:42Z
last_indexed	2023-09-18T21:15:42Z
_version_	1777411547982725120

α-glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar

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