Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica
Ipomoea aquatica Forsk is a green leafy vegetable that is a rich source of amino acids and vitamins. Antioxidant and α-glucosidase inhibitory activities of the hexane (IAHE) and methanol (IAME) fractions of the vegetable portion of I. aquatica were investigated. The IAME fraction exhibited a strong...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
ACG Publications
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/53489/ http://irep.iium.edu.my/53489/ http://irep.iium.edu.my/53489/1/lawal%20et%20al%202016.pdf http://irep.iium.edu.my/53489/7/53489-Antioxidant%20and%20%CE%B1-glucosidase%20inhibitory%20activities%20of%20isolated%20compounds%20from%20Ipomoea%20aquatica_SCOPUS.pdf |
| Summary: | Ipomoea aquatica Forsk is a green leafy vegetable that is a rich source of amino acids and vitamins. Antioxidant and α-glucosidase inhibitory activities of the hexane (IAHE) and methanol (IAME) fractions of the vegetable portion of I. aquatica were investigated. The IAME fraction exhibited a strong scavenging effect of the 2,2-diphenyl-2-picryl hydrazyl (DPPH) free radicals, and this fraction contained the highest phenolic contents. Phytochemical investigation of the IAME fraction yielded three known compounds, namely 3,5-di-O-caffeoylquinic acid (1), 4,5-di-O-caffeoylquinic acid (2) and quercetin 3-O-β-D-glucoside (3). The structures were unambiguously elucidated based on 1D and 2D-NMR analyses (1H, 13C, COSY, HSQC, HMBC) and mass spectrometry data. Compound 3 was isolated for the first time from this plant. |
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