In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract

Abstract: Currently, researchers are aiming to explore herbal plants to replace synthetic drugs because herbal plants contain high active compounds and fewer side effects. Our study was done to determine the antibacterial activity of Eurycoma longifolia Jack (E. longifolia) root using ethanol based...

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Main Authors:	Faisal, Ghasak Ghazi, Zakaria, Siti Mastura, Najmuldeen, Ghazi Faisal
Format:	Conference or Workshop Item
Language:	English English
Published:	2016
Subjects:	R Medicine (General) RB Pathology
Online Access:	http://irep.iium.edu.my/52922/ http://irep.iium.edu.my/52922/ http://irep.iium.edu.my/52922/22/Dr%20Ghassak.pdf http://irep.iium.edu.my/52922/16/ICNP2016.pdf

id	iium-52922
recordtype	eprints
spelling	iium-529222017-08-29T04:16:18Z http://irep.iium.edu.my/52922/ In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract Faisal, Ghasak Ghazi Zakaria, Siti Mastura Najmuldeen, Ghazi Faisal R Medicine (General) RB Pathology Abstract: Currently, researchers are aiming to explore herbal plants to replace synthetic drugs because herbal plants contain high active compounds and fewer side effects. Our study was done to determine the antibacterial activity of Eurycoma longifolia Jack (E. longifolia) root using ethanol based extraction method. Five types of pathogenic bacterial strains were used; Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative (Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa). Disc diffusion assay and Minimum Inhibitory Concentration (MIC) tests were used to determine the inhibition zone and turbidity of suspension which reflects the antibacterial activity of the extract. The ethanolic extract of E. longifolia Jack root extract showed positive results against Gram-positive bacteria (S. aureus and B. cereus) and Gram-negative (S. typhi). B.cereus and S.typhi showed inhibition zone values of 11.76mm and 14.33mm at the extract concentration of 150mg/ml that were higher than the positive control values (9.00, 12.67mm) respectively. However, E. coli and P. aeruginosa did not show any inhibition by the ethanol-based extract. From the results we can conclude that E.Longifolia root extract possess antibacterial activity that can be further explored to produce new medicinal products 2016-06 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/52922/22/Dr%20Ghassak.pdf application/pdf en http://irep.iium.edu.my/52922/16/ICNP2016.pdf Faisal, Ghasak Ghazi and Zakaria, Siti Mastura and Najmuldeen, Ghazi Faisal (2016) In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract. In: International Conference on Natural Products 2016 (ICNP 2016), 15-17 Mar 2016, Kuala Terengganu, Terengganu, Malaysia. http://journals.iium.edu.my/imjm/index.php/eimj/article/view/225
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	R Medicine (General) RB Pathology
spellingShingle	R Medicine (General) RB Pathology Faisal, Ghasak Ghazi Zakaria, Siti Mastura Najmuldeen, Ghazi Faisal In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract
description	Abstract: Currently, researchers are aiming to explore herbal plants to replace synthetic drugs because herbal plants contain high active compounds and fewer side effects. Our study was done to determine the antibacterial activity of Eurycoma longifolia Jack (E. longifolia) root using ethanol based extraction method. Five types of pathogenic bacterial strains were used; Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative (Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa). Disc diffusion assay and Minimum Inhibitory Concentration (MIC) tests were used to determine the inhibition zone and turbidity of suspension which reflects the antibacterial activity of the extract. The ethanolic extract of E. longifolia Jack root extract showed positive results against Gram-positive bacteria (S. aureus and B. cereus) and Gram-negative (S. typhi). B.cereus and S.typhi showed inhibition zone values of 11.76mm and 14.33mm at the extract concentration of 150mg/ml that were higher than the positive control values (9.00, 12.67mm) respectively. However, E. coli and P. aeruginosa did not show any inhibition by the ethanol-based extract. From the results we can conclude that E.Longifolia root extract possess antibacterial activity that can be further explored to produce new medicinal products
format	Conference or Workshop Item
author	Faisal, Ghasak Ghazi Zakaria, Siti Mastura Najmuldeen, Ghazi Faisal
author_facet	Faisal, Ghasak Ghazi Zakaria, Siti Mastura Najmuldeen, Ghazi Faisal
author_sort	Faisal, Ghasak Ghazi
title	In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract
title_short	In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract
title_full	In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract
title_fullStr	In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract
title_full_unstemmed	In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract
title_sort	in vitro antibacterial activity of eurycoma longifolia jack (tongkat ali) root extract
publishDate	2016
url	http://irep.iium.edu.my/52922/ http://irep.iium.edu.my/52922/ http://irep.iium.edu.my/52922/22/Dr%20Ghassak.pdf http://irep.iium.edu.my/52922/16/ICNP2016.pdf
first_indexed	2023-09-18T21:14:56Z
last_indexed	2023-09-18T21:14:56Z
_version_	1777411499424219136

In vitro antibacterial activity Of Eurycoma longifolia Jack (Tongkat Ali) root extract

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