Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups

Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups

The etiology of developing class III malocclusion and the role of craniofacial structures in this phenotype remain indistinct. The purpose of this study was to compare the relative relationship of craniofacial structures of DUSP6 gene mutation and non-mutation groups in class III malocclusion of Mal...

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Main Authors: Nowrin, Shifat A, Basri, Rehana, Alam, Mohammad Khursheed, Yusa, Tatsunori, Nakano, Junzaburo, Jaafar, Saidi, Mokhtar, Khairani Idah, Osuga, Naoto
Format: Article
Language:English
English
English
Published: The Hard Tissue Biology Network Association 2016
Subjects:
RK Dentistry
Online Access:http://irep.iium.edu.my/52843/
http://irep.iium.edu.my/52843/
http://irep.iium.edu.my/52843/
http://irep.iium.edu.my/52843/1/2016%20JHTB-%20Craniofacial%20morphology%20of%20Class%20III%20malocclusion%20with%20DUSP6%20gene-Nowryn%20et%20al%202016.pdf
http://irep.iium.edu.my/52843/7/52843-Craniofacial%20morphology%20of%20class%20III%20malocclusion%20with%20DUSP6%20gene_SCOPUS.pdf
http://irep.iium.edu.my/52843/8/52843-Craniofacial%20morphology%20of%20class%20III%20malocclusion%20with%20DUSP6%20gene_WOS.pdf
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spelling iium-528432016-11-25T03:37:44Z http://irep.iium.edu.my/52843/ Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups Nowrin, Shifat A Basri, Rehana Alam, Mohammad Khursheed Yusa, Tatsunori Nakano, Junzaburo Jaafar, Saidi Mokhtar, Khairani Idah Osuga, Naoto RK Dentistry The etiology of developing class III malocclusion and the role of craniofacial structures in this phenotype remain indistinct. The purpose of this study was to compare the relative relationship of craniofacial structures of DUSP6 gene mutation and non-mutation groups in class III malocclusion of Malaysian Malay families and their three generations. Thirty class III cephalometric radiographs of ten Malaysian Malay families including three generations with an average age 23, 54 and 79 years of each generation respectively were studied. All landmarks were positioned, determined and consequently tracings were completed Romexis software (Planmeca, Finland) to accomplish craniofacial morphology investigation. The statistical comparisons of the mutation and non-mutation group were conducted with independent t test and analysis of variance (ANOVA) was applied to evaluate the values for three generations in class III malocclusion among all measurements. The result of the current study revealed that in mutation group, there are significant differences in Co-Gn-B and SN-MDP variables compare to non-mutation group. However, almost all craniofacial variables show no significant differences among three generations. This study may suggest that in mutation group mandible is more deviated from cranial base compare to non-mutation group and there are virtually no skeletal changes among three generations with age in case of growing class III malocclusion. The Hard Tissue Biology Network Association 2016-07-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/52843/1/2016%20JHTB-%20Craniofacial%20morphology%20of%20Class%20III%20malocclusion%20with%20DUSP6%20gene-Nowryn%20et%20al%202016.pdf application/pdf en http://irep.iium.edu.my/52843/7/52843-Craniofacial%20morphology%20of%20class%20III%20malocclusion%20with%20DUSP6%20gene_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/52843/8/52843-Craniofacial%20morphology%20of%20class%20III%20malocclusion%20with%20DUSP6%20gene_WOS.pdf Nowrin, Shifat A and Basri, Rehana and Alam, Mohammad Khursheed and Yusa, Tatsunori and Nakano, Junzaburo and Jaafar, Saidi and Mokhtar, Khairani Idah and Osuga, Naoto (2016) Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups. Journal of Hard Tissue Biology, 25 (3). pp. 247-256. ISSN 1341-7649 E-ISSN 1880-828X https://www.jstage.jst.go.jp/article/jhtb/25/3/25_247/_pdf 10.2485/jhtb.25.247
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
English
topic RK Dentistry
spellingShingle RK Dentistry
Nowrin, Shifat A
Basri, Rehana
Alam, Mohammad Khursheed
Yusa, Tatsunori
Nakano, Junzaburo
Jaafar, Saidi
Mokhtar, Khairani Idah
Osuga, Naoto
Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups
description The etiology of developing class III malocclusion and the role of craniofacial structures in this phenotype remain indistinct. The purpose of this study was to compare the relative relationship of craniofacial structures of DUSP6 gene mutation and non-mutation groups in class III malocclusion of Malaysian Malay families and their three generations. Thirty class III cephalometric radiographs of ten Malaysian Malay families including three generations with an average age 23, 54 and 79 years of each generation respectively were studied. All landmarks were positioned, determined and consequently tracings were completed Romexis software (Planmeca, Finland) to accomplish craniofacial morphology investigation. The statistical comparisons of the mutation and non-mutation group were conducted with independent t test and analysis of variance (ANOVA) was applied to evaluate the values for three generations in class III malocclusion among all measurements. The result of the current study revealed that in mutation group, there are significant differences in Co-Gn-B and SN-MDP variables compare to non-mutation group. However, almost all craniofacial variables show no significant differences among three generations. This study may suggest that in mutation group mandible is more deviated from cranial base compare to non-mutation group and there are virtually no skeletal changes among three generations with age in case of growing class III malocclusion.
format Article
author Nowrin, Shifat A
Basri, Rehana
Alam, Mohammad Khursheed
Yusa, Tatsunori
Nakano, Junzaburo
Jaafar, Saidi
Mokhtar, Khairani Idah
Osuga, Naoto
author_facet Nowrin, Shifat A
Basri, Rehana
Alam, Mohammad Khursheed
Yusa, Tatsunori
Nakano, Junzaburo
Jaafar, Saidi
Mokhtar, Khairani Idah
Osuga, Naoto
author_sort Nowrin, Shifat A
title Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups
title_short Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups
title_full Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups
title_fullStr Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups
title_full_unstemmed Craniofacial morphology of class III malocclusion with DUSP6 gene: Mutation and non-mutation groups
title_sort craniofacial morphology of class iii malocclusion with dusp6 gene: mutation and non-mutation groups
publisher The Hard Tissue Biology Network Association
publishDate 2016
url http://irep.iium.edu.my/52843/
http://irep.iium.edu.my/52843/
http://irep.iium.edu.my/52843/
http://irep.iium.edu.my/52843/1/2016%20JHTB-%20Craniofacial%20morphology%20of%20Class%20III%20malocclusion%20with%20DUSP6%20gene-Nowryn%20et%20al%202016.pdf
http://irep.iium.edu.my/52843/7/52843-Craniofacial%20morphology%20of%20class%20III%20malocclusion%20with%20DUSP6%20gene_SCOPUS.pdf
http://irep.iium.edu.my/52843/8/52843-Craniofacial%20morphology%20of%20class%20III%20malocclusion%20with%20DUSP6%20gene_WOS.pdf
first_indexed 2023-09-18T21:14:52Z
last_indexed 2023-09-18T21:14:52Z
_version_ 1777411494573506560

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