Synthesize and characterization of putrescine containing sulphur

Compounds containing sulphur such as organosulphur compounds are well known for their anticancer properties. Addition of sulphur in polyamine is expected to improve the specificity due to the transport to the targeted cells efficiently via polyamine transport system added with the anticancer propert...

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Bibliographic Details
Main Authors: Sahabudin, Adzly H, Fong, Fiona H, Abdul Ghani, Radiah
Format: Conference or Workshop Item
Language:English
Published: Bahagian Hal Ehwal Akademik, Universiti Teknologi MARA Cawangan Pulau Pinang 2016
Subjects:
Online Access:http://irep.iium.edu.my/52679/
http://irep.iium.edu.my/52679/
http://irep.iium.edu.my/52679/8/52679.pdf
Description
Summary:Compounds containing sulphur such as organosulphur compounds are well known for their anticancer properties. Addition of sulphur in polyamine is expected to improve the specificity due to the transport to the targeted cells efficiently via polyamine transport system added with the anticancer properties possess by the sulphur donor atom. Putrescine with a polyamine moiety acted as cell delivery vector was synthesized to incorporate sulphur into the structure. The synthesized product was later characterized using various physicochemical techniques for structural determination.