High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series

Hypoxemia in severe leptospirosis-associated pulmonary hemorrhage syndrome (LPHS) is a challenging clinical scenario not usually responsive to maximal support on mechanical ventilation. We described the efficacy and safety of high frequency oscillatory ventilation (HFOV) as rescue therapy in acute r...

Full description

Bibliographic Details
Main Authors:	Mat Nor, Mohd Basri, Md Ralib, Azrina, Ibrahim, Nor Airini, Abdul-Ghani, Muhammad Rasydan
Format:	Article
Language:	English English English
Published:	Indian Society of Critical Care Medicine 2016
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/52497/ http://irep.iium.edu.my/52497/ http://irep.iium.edu.my/52497/7/52497.pdf http://irep.iium.edu.my/52497/8/52497-High%20frequency%20oscillatory%20ventilation%20in%20leptospirosis%20pulmonary%20hemorrhage%20syndrome_SCOPUS.pdf http://irep.iium.edu.my/52497/9/52497-High%20frequency%20oscillatory%20ventilation%20in%20leptospirosis%20pulmonary%20hemorrhage%20syndrome_WOS.pdf

id	iium-52497
recordtype	eprints
spelling	iium-524972017-04-06T08:11:02Z http://irep.iium.edu.my/52497/ High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series Mat Nor, Mohd Basri Md Ralib, Azrina Ibrahim, Nor Airini Abdul-Ghani, Muhammad Rasydan R Medicine (General) Hypoxemia in severe leptospirosis-associated pulmonary hemorrhage syndrome (LPHS) is a challenging clinical scenario not usually responsive to maximal support on mechanical ventilation. We described the efficacy and safety of high frequency oscillatory ventilation (HFOV) as rescue therapy in acute respiratory failure secondary to LPHS. This is a retrospective case study of five patients with diagnosis of severe LPHS, who were admitted to Intensive Care Unit from October 2014 to January 2015. They developed refractory hypoxemia on conventional mechanical ventilation and rescue therapy was indicated. All patients responded rapidly by showing improvements in oxygen index and PaO2/FiO2 ratio within first 72 h of therapy. Despite severity of illness evidenced by high Simplified Acute Physiological II and Sequential Organ Failure Assessment scores, all patients were discharged from hospital alive. In view of the rapid onset and extent of hemorrhage which may culminate quickly into asphyxiation and death, HFOV may indeed be lifesaving in severe LPHS. Indian Society of Critical Care Medicine 2016-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/52497/7/52497.pdf application/pdf en http://irep.iium.edu.my/52497/8/52497-High%20frequency%20oscillatory%20ventilation%20in%20leptospirosis%20pulmonary%20hemorrhage%20syndrome_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/52497/9/52497-High%20frequency%20oscillatory%20ventilation%20in%20leptospirosis%20pulmonary%20hemorrhage%20syndrome_WOS.pdf Mat Nor, Mohd Basri and Md Ralib, Azrina and Ibrahim, Nor Airini and Abdul-Ghani, Muhammad Rasydan (2016) High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series. Indian Journal of Critical Care Medicine, 20 (6). pp. 342-348. ISSN 0972-5229 http://www.ijccm.org/temp/IJCCM206342-1226681_032426.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Mat Nor, Mohd Basri Md Ralib, Azrina Ibrahim, Nor Airini Abdul-Ghani, Muhammad Rasydan High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series
description	Hypoxemia in severe leptospirosis-associated pulmonary hemorrhage syndrome (LPHS) is a challenging clinical scenario not usually responsive to maximal support on mechanical ventilation. We described the efficacy and safety of high frequency oscillatory ventilation (HFOV) as rescue therapy in acute respiratory failure secondary to LPHS. This is a retrospective case study of five patients with diagnosis of severe LPHS, who were admitted to Intensive Care Unit from October 2014 to January 2015. They developed refractory hypoxemia on conventional mechanical ventilation and rescue therapy was indicated. All patients responded rapidly by showing improvements in oxygen index and PaO2/FiO2 ratio within first 72 h of therapy. Despite severity of illness evidenced by high Simplified Acute Physiological II and Sequential Organ Failure Assessment scores, all patients were discharged from hospital alive. In view of the rapid onset and extent of hemorrhage which may culminate quickly into asphyxiation and death, HFOV may indeed be lifesaving in severe LPHS.
format	Article
author	Mat Nor, Mohd Basri Md Ralib, Azrina Ibrahim, Nor Airini Abdul-Ghani, Muhammad Rasydan
author_facet	Mat Nor, Mohd Basri Md Ralib, Azrina Ibrahim, Nor Airini Abdul-Ghani, Muhammad Rasydan
author_sort	Mat Nor, Mohd Basri
title	High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series
title_short	High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series
title_full	High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series
title_fullStr	High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series
title_full_unstemmed	High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series
title_sort	high frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: a case series
publisher	Indian Society of Critical Care Medicine
publishDate	2016
url	http://irep.iium.edu.my/52497/ http://irep.iium.edu.my/52497/ http://irep.iium.edu.my/52497/7/52497.pdf http://irep.iium.edu.my/52497/8/52497-High%20frequency%20oscillatory%20ventilation%20in%20leptospirosis%20pulmonary%20hemorrhage%20syndrome_SCOPUS.pdf http://irep.iium.edu.my/52497/9/52497-High%20frequency%20oscillatory%20ventilation%20in%20leptospirosis%20pulmonary%20hemorrhage%20syndrome_WOS.pdf
first_indexed	2023-09-18T21:14:22Z
last_indexed	2023-09-18T21:14:22Z
_version_	1777411463810383872

High frequency oscillatory ventilation in leptospirosis pulmonary haemorrhage: A case series

Similar Items