Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics

The metabolites of Clinacanthus nutans leaves extracts and their dependence on drying process were systematically characterized using 1H nuclear magnetic resonance spectroscopy (NMR) multivariate data analysis. Principal component analysis (PCA) and partial least square-discriminant analysis (PLS-DA...

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Main Authors:	Noor Hashim, Noor Haslinda, Latip, Jalifah, Khatib, Alfi
Format:	Conference or Workshop Item
Language:	English English English
Published:	AIP Publishing 2016
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/52299/ http://irep.iium.edu.my/52299/ http://irep.iium.edu.my/52299/ http://irep.iium.edu.my/52299/13/hashim2016.pdf http://irep.iium.edu.my/52299/1/52299_Metabolite%20profiling%20of%20Clinacanthus_MYRA.pdf http://irep.iium.edu.my/52299/2/52299_Metabolite%20profiling%20of%20Clinacanthus_SCOPUS.pdf

id	iium-52299
recordtype	eprints
spelling	iium-522992019-10-14T01:59:53Z http://irep.iium.edu.my/52299/ Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics Noor Hashim, Noor Haslinda Latip, Jalifah Khatib, Alfi RM Therapeutics. Pharmacology The metabolites of Clinacanthus nutans leaves extracts and their dependence on drying process were systematically characterized using 1H nuclear magnetic resonance spectroscopy (NMR) multivariate data analysis. Principal component analysis (PCA) and partial least square-discriminant analysis (PLS-DA) were able to distinguish the leaves extracts obtained from different drying methods. The identified metabolites were carbohydrates, amino acid, flavonoids and sulfur glucoside compounds. The major metabolites responsible for the separation in PLS-DA loading plots were lupeol, cycloclinacosides, betulin, cerebrosides and choline. The results showed that the combination of 1H NMR spectroscopy and multivariate data analyses could act as an efficient technique to understand the C. nutans composition and its variation. © 2016 Author(s). AIP Publishing 2016-11-17 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/52299/13/hashim2016.pdf application/pdf en http://irep.iium.edu.my/52299/1/52299_Metabolite%20profiling%20of%20Clinacanthus_MYRA.pdf application/pdf en http://irep.iium.edu.my/52299/2/52299_Metabolite%20profiling%20of%20Clinacanthus_SCOPUS.pdf Noor Hashim, Noor Haslinda and Latip, Jalifah and Khatib, Alfi (2016) Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics. In: 2016 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2016, 13th-14th April 2016, Selangor. http://aip.scitation.org/doi/abs/10.1063/1.4966753 10.1063/1.4966753
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Noor Hashim, Noor Haslinda Latip, Jalifah Khatib, Alfi Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics
description	The metabolites of Clinacanthus nutans leaves extracts and their dependence on drying process were systematically characterized using 1H nuclear magnetic resonance spectroscopy (NMR) multivariate data analysis. Principal component analysis (PCA) and partial least square-discriminant analysis (PLS-DA) were able to distinguish the leaves extracts obtained from different drying methods. The identified metabolites were carbohydrates, amino acid, flavonoids and sulfur glucoside compounds. The major metabolites responsible for the separation in PLS-DA loading plots were lupeol, cycloclinacosides, betulin, cerebrosides and choline. The results showed that the combination of 1H NMR spectroscopy and multivariate data analyses could act as an efficient technique to understand the C. nutans composition and its variation. © 2016 Author(s).
format	Conference or Workshop Item
author	Noor Hashim, Noor Haslinda Latip, Jalifah Khatib, Alfi
author_facet	Noor Hashim, Noor Haslinda Latip, Jalifah Khatib, Alfi
author_sort	Noor Hashim, Noor Haslinda
title	Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics
title_short	Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics
title_full	Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics
title_fullStr	Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics
title_full_unstemmed	Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics
title_sort	metabolite profiling of clinacanthus nutans leaves extracts obtained from different drying methods by 1h nmr-based metabolomics
publisher	AIP Publishing
publishDate	2016
url	http://irep.iium.edu.my/52299/ http://irep.iium.edu.my/52299/ http://irep.iium.edu.my/52299/ http://irep.iium.edu.my/52299/13/hashim2016.pdf http://irep.iium.edu.my/52299/1/52299_Metabolite%20profiling%20of%20Clinacanthus_MYRA.pdf http://irep.iium.edu.my/52299/2/52299_Metabolite%20profiling%20of%20Clinacanthus_SCOPUS.pdf
first_indexed	2023-09-18T21:14:07Z
last_indexed	2023-09-18T21:14:07Z
_version_	1777411447343546368

Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics

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