Silk in biomedical engineering: A review

The astounding biomaterial features of silk for example its high mechanical strength, biocompatibility and degradability have led to plethoric study on the silk properties. Tissue engineering and regenerative medicine are the fields that have been widely explored using silk scaffolds due to their me...

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Main Authors:	Zubir, Nazira, Pushpanathan,, K
Format:	Article
Language:	English
Published:	International Journal of Engineering Inventions (IJEI) 2016
Subjects:	TA401 Materials of engineering and construction
Online Access:	http://irep.iium.edu.my/52259/ http://irep.iium.edu.my/52259/ http://irep.iium.edu.my/52259/1/C0581829.pdf

id	iium-52259
recordtype	eprints
spelling	iium-522592017-03-06T05:53:08Z http://irep.iium.edu.my/52259/ Silk in biomedical engineering: A review Zubir, Nazira Pushpanathan,, K TA401 Materials of engineering and construction The astounding biomaterial features of silk for example its high mechanical strength, biocompatibility and degradability have led to plethoric study on the silk properties. Tissue engineering and regenerative medicine are the fields that have been widely explored using silk scaffolds due to their mechanical stability. The mechanical stability of the scaffold is vital for the cells to adhere, expand, divide, proliferate and differentiate. Various types of connective tissues for examples tendon, ligament, bone and cartilage have been used. Apart from that, the scaffold should also display remarkable biocompatibility feature, should be porous with high surface area, should match the target tissue and reproducible. Another important aspect of the scaffold that needs significant consideration is the usage of nanoscale structure for the cells to be able to recognize and elicit response. Hence, nanofibres is the most suitable format of the artificial matrices to be considered in the tissue engineering technique. Inexpensive and simple approach pertaining to nanofibres approach is electrospinning method which capable to be scaled up and to produce 3 dimensional, porous structure with high surface area. Vast studies on the tissue engineering pertaining to silk and the silk regenerative properties have been associated with the impressive mechanical strength of the silk. International Journal of Engineering Inventions (IJEI) 2016-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/52259/1/C0581829.pdf Zubir, Nazira and Pushpanathan,, K (2016) Silk in biomedical engineering: A review. International Journal of Engineering Inventions (IJEI), 5 (8). pp. 18-29. ISSN 2319-6491 E-ISSN 2278-7461 http://www.ijeijournal.com/papers/Vol.5-Iss.8/C0581829.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TA401 Materials of engineering and construction
spellingShingle	TA401 Materials of engineering and construction Zubir, Nazira Pushpanathan,, K Silk in biomedical engineering: A review
description	The astounding biomaterial features of silk for example its high mechanical strength, biocompatibility and degradability have led to plethoric study on the silk properties. Tissue engineering and regenerative medicine are the fields that have been widely explored using silk scaffolds due to their mechanical stability. The mechanical stability of the scaffold is vital for the cells to adhere, expand, divide, proliferate and differentiate. Various types of connective tissues for examples tendon, ligament, bone and cartilage have been used. Apart from that, the scaffold should also display remarkable biocompatibility feature, should be porous with high surface area, should match the target tissue and reproducible. Another important aspect of the scaffold that needs significant consideration is the usage of nanoscale structure for the cells to be able to recognize and elicit response. Hence, nanofibres is the most suitable format of the artificial matrices to be considered in the tissue engineering technique. Inexpensive and simple approach pertaining to nanofibres approach is electrospinning method which capable to be scaled up and to produce 3 dimensional, porous structure with high surface area. Vast studies on the tissue engineering pertaining to silk and the silk regenerative properties have been associated with the impressive mechanical strength of the silk.
format	Article
author	Zubir, Nazira Pushpanathan,, K
author_facet	Zubir, Nazira Pushpanathan,, K
author_sort	Zubir, Nazira
title	Silk in biomedical engineering: A review
title_short	Silk in biomedical engineering: A review
title_full	Silk in biomedical engineering: A review
title_fullStr	Silk in biomedical engineering: A review
title_full_unstemmed	Silk in biomedical engineering: A review
title_sort	silk in biomedical engineering: a review
publisher	International Journal of Engineering Inventions (IJEI)
publishDate	2016
url	http://irep.iium.edu.my/52259/ http://irep.iium.edu.my/52259/ http://irep.iium.edu.my/52259/1/C0581829.pdf
first_indexed	2023-09-18T21:14:04Z
last_indexed	2023-09-18T21:14:04Z
_version_	1777411444576354304

Silk in biomedical engineering: A review

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