Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes

Metallic silver (Ag) and some Ag compounds have long being used to fight microbial infection even before the emergence of antibiotics. But lately, one of the problems facing the medical world is the occurrence of drug resistance microbes. Therefore, actions must be taken to reduce the problem, one...

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Main Authors:	Chowdhury, Silvia, Yusof, Faridah, Sulaiman, Nadzril, Faruck, Mohammad Omer
Format:	Conference or Workshop Item
Language:	English
Published:	Kulliyah of Engineering, International Islamic University Malaysia 2016
Subjects:	TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/51730/ http://irep.iium.edu.my/51730/ http://irep.iium.edu.my/51730/1/51730.pdf

id	iium-51730
recordtype	eprints
spelling	iium-517302016-08-22T00:56:46Z http://irep.iium.edu.my/51730/ Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes Chowdhury, Silvia Yusof, Faridah Sulaiman, Nadzril Faruck, Mohammad Omer TP248.13 Biotechnology Metallic silver (Ag) and some Ag compounds have long being used to fight microbial infection even before the emergence of antibiotics. But lately, one of the problems facing the medical world is the occurrence of drug resistance microbes. Therefore, actions must be taken to reduce the problem, one of which is to continue studies to develop new drug, either synthetic or natural. The ultimate goal is to offer appropriate and efficient antimicrobial drug to the patient. In this regard, with the advent of nanotechnology, it is now possible to synthesize nano scale Ag which can be used in diverse medical applications. The aim of this study is to investigate the effect of some important parameters towards the production of high yield Ag nanoparticles (AgNPs) from silver salts using reducing agent. Based on the analyses by its yellow color, UV-vis in the range of 350 to 420 nm wavelength and surface plasmon resonance (SPR) at 420 nm, AgNPs produced were estimated to be in the range of 10 to 15 nm in diameter. Out of five parameters tested, such as silver nitrate (AgNO3) concentration, stirring time, pH of aqueous AgNO3, tri-sodium citrate concentration and reaction time, results showed that all factors except stirring time affects the production. Characterization of AgNPs, carried out using transmission electron microscope (TEM), showed that the synthesized AgNPs were spherical with diameters less than 15 nm. Antimicrobial activity assays, carried out against selected microbes, namely Aspergillus niger, Microsporum canis and Staphylococcus aureus showed various degree of potencies Kulliyah of Engineering, International Islamic University Malaysia 2016 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/51730/1/51730.pdf Chowdhury, Silvia and Yusof, Faridah and Sulaiman, Nadzril and Faruck, Mohammad Omer (2016) Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes. In: 4th International Conference on Biotechnology Engineering 2016 (ICBioE 2016), 25th-27th July 2016, Kuala Lumpur. http://www.iium.edu.my/icbioe/2016/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TP248.13 Biotechnology
spellingShingle	TP248.13 Biotechnology Chowdhury, Silvia Yusof, Faridah Sulaiman, Nadzril Faruck, Mohammad Omer Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes
description	Metallic silver (Ag) and some Ag compounds have long being used to fight microbial infection even before the emergence of antibiotics. But lately, one of the problems facing the medical world is the occurrence of drug resistance microbes. Therefore, actions must be taken to reduce the problem, one of which is to continue studies to develop new drug, either synthetic or natural. The ultimate goal is to offer appropriate and efficient antimicrobial drug to the patient. In this regard, with the advent of nanotechnology, it is now possible to synthesize nano scale Ag which can be used in diverse medical applications. The aim of this study is to investigate the effect of some important parameters towards the production of high yield Ag nanoparticles (AgNPs) from silver salts using reducing agent. Based on the analyses by its yellow color, UV-vis in the range of 350 to 420 nm wavelength and surface plasmon resonance (SPR) at 420 nm, AgNPs produced were estimated to be in the range of 10 to 15 nm in diameter. Out of five parameters tested, such as silver nitrate (AgNO3) concentration, stirring time, pH of aqueous AgNO3, tri-sodium citrate concentration and reaction time, results showed that all factors except stirring time affects the production. Characterization of AgNPs, carried out using transmission electron microscope (TEM), showed that the synthesized AgNPs were spherical with diameters less than 15 nm. Antimicrobial activity assays, carried out against selected microbes, namely Aspergillus niger, Microsporum canis and Staphylococcus aureus showed various degree of potencies
format	Conference or Workshop Item
author	Chowdhury, Silvia Yusof, Faridah Sulaiman, Nadzril Faruck, Mohammad Omer
author_facet	Chowdhury, Silvia Yusof, Faridah Sulaiman, Nadzril Faruck, Mohammad Omer
author_sort	Chowdhury, Silvia
title	Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes
title_short	Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes
title_full	Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes
title_fullStr	Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes
title_full_unstemmed	Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes
title_sort	effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes
publisher	Kulliyah of Engineering, International Islamic University Malaysia
publishDate	2016
url	http://irep.iium.edu.my/51730/ http://irep.iium.edu.my/51730/ http://irep.iium.edu.my/51730/1/51730.pdf
first_indexed	2023-09-18T21:13:18Z
last_indexed	2023-09-18T21:13:18Z
_version_	1777411396485513216

Effect of some parameters in the synthesis of silver nanoparticles and its evaluation as antimicrobes

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