Label-free microfluidic blood cells micro-separator

Blood cells separation is of great interest in many biomedical applications because of its importance in sample preparation for both clinical diagnosis and therapeutic research. In this work, the micro-separator uses the combination of magnetophoresis with hydrodynamics in order to separate whit...

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Main Authors:	Aissa, Foughalia, Ibrahim, Siti Noorjannah
Format:	Conference or Workshop Item
Language:	English English
Published:	IEEE 2016
Subjects:	TK452 Electric apparatus and materials. Electric circuits. Electric networks TK7885 Computer engineering
Online Access:	http://irep.iium.edu.my/51267/ http://irep.iium.edu.my/51267/ http://irep.iium.edu.my/51267/ http://irep.iium.edu.my/51267/5/51267-new.pdf http://irep.iium.edu.my/51267/8/51267_label%20free%20microfluidic_scopus.pdf

id	iium-51267
recordtype	eprints
spelling	iium-512672017-01-10T03:19:24Z http://irep.iium.edu.my/51267/ Label-free microfluidic blood cells micro-separator Aissa, Foughalia Ibrahim, Siti Noorjannah TK452 Electric apparatus and materials. Electric circuits. Electric networks TK7885 Computer engineering Blood cells separation is of great interest in many biomedical applications because of its importance in sample preparation for both clinical diagnosis and therapeutic research. In this work, the micro-separator uses the combination of magnetophoresis with hydrodynamics in order to separate white blood cells (WBCs) and red blood cells (RBCs) by taking into account the magnetization of the ferromagnetic elements and fluidic forces on the cells. The microfluidic devices can achieve label-free, continuous separation of WBCs and RBCs with relatively high efficiency. The micro-separator utilizes hydrodynamic force acting on cells within laminar flow, coupled with magnetophoresis force in novel U-shaped micro-channel. Here, we report the separation efficiency of the microfluidic device in continuous flow based on results of a 3D model simulation conducted in COMSOL Multiphysics. The proposed device enables label-free cell separation and thus, it can be a useful microfluidic component for lab-on-a-chip system and integrated biological and biomedical applications. IEEE 2016-05 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/51267/5/51267-new.pdf application/pdf en http://irep.iium.edu.my/51267/8/51267_label%20free%20microfluidic_scopus.pdf Aissa, Foughalia and Ibrahim, Siti Noorjannah (2016) Label-free microfluidic blood cells micro-separator. In: 2016 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), 30th May-2nd June 2016, Budapest, Hungary. http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=7514861&filter%3DAND%28p_IS_Number%3A7514818%29%26rowsPerPage%3D75 10.1109/DTIP.2016.7514861
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	TK452 Electric apparatus and materials. Electric circuits. Electric networks TK7885 Computer engineering
spellingShingle	TK452 Electric apparatus and materials. Electric circuits. Electric networks TK7885 Computer engineering Aissa, Foughalia Ibrahim, Siti Noorjannah Label-free microfluidic blood cells micro-separator
description	Blood cells separation is of great interest in many biomedical applications because of its importance in sample preparation for both clinical diagnosis and therapeutic research. In this work, the micro-separator uses the combination of magnetophoresis with hydrodynamics in order to separate white blood cells (WBCs) and red blood cells (RBCs) by taking into account the magnetization of the ferromagnetic elements and fluidic forces on the cells. The microfluidic devices can achieve label-free, continuous separation of WBCs and RBCs with relatively high efficiency. The micro-separator utilizes hydrodynamic force acting on cells within laminar flow, coupled with magnetophoresis force in novel U-shaped micro-channel. Here, we report the separation efficiency of the microfluidic device in continuous flow based on results of a 3D model simulation conducted in COMSOL Multiphysics. The proposed device enables label-free cell separation and thus, it can be a useful microfluidic component for lab-on-a-chip system and integrated biological and biomedical applications.
format	Conference or Workshop Item
author	Aissa, Foughalia Ibrahim, Siti Noorjannah
author_facet	Aissa, Foughalia Ibrahim, Siti Noorjannah
author_sort	Aissa, Foughalia
title	Label-free microfluidic blood cells micro-separator
title_short	Label-free microfluidic blood cells micro-separator
title_full	Label-free microfluidic blood cells micro-separator
title_fullStr	Label-free microfluidic blood cells micro-separator
title_full_unstemmed	Label-free microfluidic blood cells micro-separator
title_sort	label-free microfluidic blood cells micro-separator
publisher	IEEE
publishDate	2016
url	http://irep.iium.edu.my/51267/ http://irep.iium.edu.my/51267/ http://irep.iium.edu.my/51267/ http://irep.iium.edu.my/51267/5/51267-new.pdf http://irep.iium.edu.my/51267/8/51267_label%20free%20microfluidic_scopus.pdf
first_indexed	2023-09-18T21:12:34Z
last_indexed	2023-09-18T21:12:34Z
_version_	1777411350267428864

Label-free microfluidic blood cells micro-separator

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