Angiogenic potential of extracellular matrix of human amniotic membrane
Combination between tissue engineering and other fields has brought an innovation in the area of regenerative medicine which ultimate aims are to repair, improve, and produce a good tissue construct. The availability of many types of scaffold, both synthetically and naturally have developed into man...
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2016
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iium-510832017-07-12T04:08:16Z http://irep.iium.edu.my/51083/ Angiogenic potential of extracellular matrix of human amniotic membrane Md Hashim, Siti Nurnasihah Hilmi Yusof, Muhammad Fuad Zahari, Wafa’ Ahmad Amin Noordin, Khairul Bariah Kannan, Thirumulu Ponnuraj Sheikh Abdul Hamid, Suzina Mokhtar@Makhtar, Khairani Idah Ahmad, Azlina RK Dentistry Combination between tissue engineering and other fields has brought an innovation in the area of regenerative medicine which ultimate aims are to repair, improve, and produce a good tissue construct. The availability of many types of scaffold, both synthetically and naturally have developed into many outstanding end products that have achieved the general objective in tissue engineering. Interestingly, most of this scaffold emulates extracellular matrix (ECM) characteristics. Therefore, ECM component sparks an interest to be explored and manipulated. The ECM featured in human amniotic membrane (HAM) provides a suitable niche for the cells to adhere, grow, proliferate, migrate and differentiate, and could possibly contribute to the production of angiogenic micro-environment indirectly. Previously, HAM scaffold has been widely used to accelerate wound healing, treat bone related and ocular diseases, and involved in cardiovascular repair. Also, it has been used in the angiogenicity study, but with a different technical approach. In addition, both side of HAM could be used in cellularised and decellularised conditions depending on the objectives of a particular research. Therefore, it is of paramount importance to investigate the behavior of ECM components especially on the stromal side of HAM and further explore the angiogenic potential exhibited by this scaffold. Kluwer Academic Publishers-Springer 2016-06-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/51083/1/Angiogenic_potential_of_extracellular_matrix_of_human_amniotic_membrane-2016_TERM.pdf application/pdf en http://irep.iium.edu.my/51083/4/51083-Angiogenic_Potential_of_Extracellular_Matrix_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/51083/5/51083-Angiogenic_Potential_of_Extracellular_Matrix_WOS.pdf Md Hashim, Siti Nurnasihah and Hilmi Yusof, Muhammad Fuad and Zahari, Wafa’ and Ahmad Amin Noordin, Khairul Bariah and Kannan, Thirumulu Ponnuraj and Sheikh Abdul Hamid, Suzina and Mokhtar@Makhtar, Khairani Idah and Ahmad, Azlina (2016) Angiogenic potential of extracellular matrix of human amniotic membrane. Tissue Engineering and Regenerative Medicine, 13 ( 3). pp. 211-217. ISSN 1738-2696 E-ISSN 2212-5469 http://link.springer.com/article/10.1007/s13770-016-9057-6 10.1007/s13770-016-9057-6 |
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RK Dentistry |
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RK Dentistry Md Hashim, Siti Nurnasihah Hilmi Yusof, Muhammad Fuad Zahari, Wafa’ Ahmad Amin Noordin, Khairul Bariah Kannan, Thirumulu Ponnuraj Sheikh Abdul Hamid, Suzina Mokhtar@Makhtar, Khairani Idah Ahmad, Azlina Angiogenic potential of extracellular matrix of human amniotic membrane |
description |
Combination between tissue engineering and other fields has brought an innovation in the area of regenerative medicine which ultimate aims are to repair, improve, and produce a good tissue construct. The availability of many types of scaffold, both synthetically and naturally have developed into many outstanding end products that have achieved the general objective in tissue engineering. Interestingly, most of this scaffold emulates extracellular matrix (ECM) characteristics. Therefore, ECM component sparks an interest to be explored and manipulated. The ECM featured in human amniotic membrane (HAM) provides a suitable niche for the cells to adhere, grow, proliferate, migrate and differentiate, and could possibly contribute to the production of angiogenic micro-environment indirectly. Previously, HAM scaffold has been widely used to accelerate wound healing, treat bone related and ocular diseases, and involved in cardiovascular repair. Also, it has been used in the angiogenicity study, but with a different technical approach. In addition, both side of HAM could be used in cellularised and decellularised conditions depending on the objectives of a particular research. Therefore, it is of paramount importance to investigate the behavior of ECM components especially on the stromal side of HAM and further explore the angiogenic potential exhibited by this scaffold. |
format |
Article |
author |
Md Hashim, Siti Nurnasihah Hilmi Yusof, Muhammad Fuad Zahari, Wafa’ Ahmad Amin Noordin, Khairul Bariah Kannan, Thirumulu Ponnuraj Sheikh Abdul Hamid, Suzina Mokhtar@Makhtar, Khairani Idah Ahmad, Azlina |
author_facet |
Md Hashim, Siti Nurnasihah Hilmi Yusof, Muhammad Fuad Zahari, Wafa’ Ahmad Amin Noordin, Khairul Bariah Kannan, Thirumulu Ponnuraj Sheikh Abdul Hamid, Suzina Mokhtar@Makhtar, Khairani Idah Ahmad, Azlina |
author_sort |
Md Hashim, Siti Nurnasihah |
title |
Angiogenic potential of extracellular matrix of human amniotic membrane |
title_short |
Angiogenic potential of extracellular matrix of human amniotic membrane |
title_full |
Angiogenic potential of extracellular matrix of human amniotic membrane |
title_fullStr |
Angiogenic potential of extracellular matrix of human amniotic membrane |
title_full_unstemmed |
Angiogenic potential of extracellular matrix of human amniotic membrane |
title_sort |
angiogenic potential of extracellular matrix of human amniotic membrane |
publisher |
Kluwer Academic Publishers-Springer |
publishDate |
2016 |
url |
http://irep.iium.edu.my/51083/ http://irep.iium.edu.my/51083/ http://irep.iium.edu.my/51083/ http://irep.iium.edu.my/51083/1/Angiogenic_potential_of_extracellular_matrix_of_human_amniotic_membrane-2016_TERM.pdf http://irep.iium.edu.my/51083/4/51083-Angiogenic_Potential_of_Extracellular_Matrix_SCOPUS.pdf http://irep.iium.edu.my/51083/5/51083-Angiogenic_Potential_of_Extracellular_Matrix_WOS.pdf |
first_indexed |
2023-09-18T21:12:16Z |
last_indexed |
2023-09-18T21:12:16Z |
_version_ |
1777411331943563264 |