Two isolated crystalline solids from the stem of Entada spiralis Ridl.(akar Sintok) = Pemencilan dua jenis pepejal kristal dari batang pokok Entada spiralis (Akar Sintok)
Entada spiralis Ridl. (Leguminosae) is a woody climber which locally known as ‘akar sintok’. The isolation and structure determination of two crystalline solids from active methanol fraction of E. spiralis stem bark had been examined. The structure identification of both solids was based on spectr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English English |
| Published: |
The Malaysian Analytical Sciences Society
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/51033/ http://irep.iium.edu.my/51033/ http://irep.iium.edu.my/51033/1/Aiza_20_2_4.pdf http://irep.iium.edu.my/51033/4/51033_Two%20isolated%20crystalline%20solids%20from%20the%20stem%20of%20entada%20spiralis_Scopus.pdf |
| Summary: | Entada spiralis Ridl. (Leguminosae) is a woody climber which locally known as ‘akar sintok’. The isolation and structure
determination of two crystalline solids from active methanol fraction of E. spiralis stem bark had been examined. The structure
identification of both solids was based on spectroscopic data (1
H and 13C NMR, HMQC, HMBC, DEPT135 and MS) along with
comparison with literature data. The results revealed that these two crystalline solid sugars isolated from the most active fraction
were known as penta-2-acetoxy-β-D-digitoxopyranosyl-(1→2)-fructofuranosyl-(6→4)-β-D-glucopyranosyl-(1→4)-
glucopyranosyl-(1→2)-β-D fructofuranosyl-(6→1)-β-D-glucopyranosyl-(4→1)-acetylglucosamine (1) and β,D-glucopyranosyl(1→2)-β,D-glucopyranosyl)-(1→3)-β,D-xylopyranosyl(1→4)-α,L-rhamnopyranosyl)-(1→3)-β,D-
glucopyranosyl(1→3)-
β,D-glucopyranoside (2) Thus, this finding can be utilized as a scientific baseline information for further skin disease studies,
since both constituents were isolated from moderate antidermatophytic active fraction.
Pemencilan dan penentuan struktur dua komponen bersifat kristal dari batang pokok E. spiralis yang juga dikenali sebagai akar
sintok telah dijalankan. Eksperimen penentuan struktur berdasarkan data – data spektroskopi menggunakan 1
H, 13C NMR,
HMQC, HMBC, DEPT135 dan spektrometer jisim dan juga perbandingan dengan kajian terdahulu. Hasil analisa spektroskopi
yang terperinci menunjukkan kedua – dua kristal tersebut dikenali sebagai penta-2-asetoksi-β-D-digitoxopiranosil-(1→2)-
fruktofuranosil-(6→4)-β-D-glukopiranosil-(1→4)-glukopiranosil-(1→2)-β-D fruktofuranosil-(6→1)-β-D-glukopiranosil-(4→1)-
acetilglukosamina (1) and β,D-glukopiranosil(1→2)-β,D-glukpiranosil)-(1→3)-β,D-xilopiranosil(1→4)-α,L-rhamnopiranosil)-
(1→3)-β,D-glukopiranosil(1→3)-β,D-glukopiranosid (2). Penemuan ini boleh dijadikan maklumat asas untuk kajian penyakit
kulit kerana kedua-dua komponen ini dipencilkan dari fraksi metanol yang bersifat antiderma. |
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