The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom

Tamarind (Tamarindus indica) has been used as medical plant for treating many human and animal diseases and widely used as a traditional herbal medicine for the treatment of snake bites. The objective of the study is to investigate whether tamarind seed extract have neutralization activity on advers...

Full description

Bibliographic Details
Main Authors:	Al-Ani, Imad Matloub Dally, Ismail, Soraya, Maung, Khin M., Oothuman, Pakeer
Format:	Conference or Workshop Item
Language:	English English
Published:	2015
Subjects:	QM Human anatomy RB Pathology
Online Access:	http://irep.iium.edu.my/50960/ http://irep.iium.edu.my/50960/4/Certificate_Nah_Con.jpg http://irep.iium.edu.my/50960/17/50960.pdf

id	iium-50960
recordtype	eprints
spelling	iium-509602016-07-19T01:14:04Z http://irep.iium.edu.my/50960/ The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom Al-Ani, Imad Matloub Dally Ismail, Soraya Maung, Khin M. Oothuman, Pakeer QM Human anatomy RB Pathology Tamarind (Tamarindus indica) has been used as medical plant for treating many human and animal diseases and widely used as a traditional herbal medicine for the treatment of snake bites. The objective of the study is to investigate whether tamarind seed extract have neutralization activity on adverse histological reaction against venoms of the King Cobra. Twenty healthy mature male mice were randomly divided into 4 groups with 5 mice in each. The control group was injected with 1 ml of normal saline. The second group was injected subcutaneously with a single dose of 24.96µg/20g King Cobra venom (KCV) solution. The third group was injected with the same dose of KCV solution and 10mg/20g of Tamarind seed extract (TSE). The fourth group was injected with the same dose of KCV solution and 15mg/20g TSE solution. The animals were sacrificed after 24 hours of injection of the solution. Fragments of muscle, kidney and liver were fixed in 10% neutral buffered formalin, and processed for light microscopical studies. The result showed that TSE reduced the histopathological changes induced by the King Cobra venom in the muscles, livers and kidneys and the improvement was proportional to the applied dose of the TSE indicating that tamarind seed extract prevents adverse histological changes in the muscle, liver and kidney. 2015-12 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/50960/4/Certificate_Nah_Con.jpg application/pdf en http://irep.iium.edu.my/50960/17/50960.pdf Al-Ani, Imad Matloub Dally and Ismail, Soraya and Maung, Khin M. and Oothuman, Pakeer (2015) The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom. In: The 9th Scientific conference, College of Medicine, Al-Nahrain University, 21-22 December 2015, Baghdad, Iraq. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QM Human anatomy RB Pathology
spellingShingle	QM Human anatomy RB Pathology Al-Ani, Imad Matloub Dally Ismail, Soraya Maung, Khin M. Oothuman, Pakeer The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom
description	Tamarind (Tamarindus indica) has been used as medical plant for treating many human and animal diseases and widely used as a traditional herbal medicine for the treatment of snake bites. The objective of the study is to investigate whether tamarind seed extract have neutralization activity on adverse histological reaction against venoms of the King Cobra. Twenty healthy mature male mice were randomly divided into 4 groups with 5 mice in each. The control group was injected with 1 ml of normal saline. The second group was injected subcutaneously with a single dose of 24.96µg/20g King Cobra venom (KCV) solution. The third group was injected with the same dose of KCV solution and 10mg/20g of Tamarind seed extract (TSE). The fourth group was injected with the same dose of KCV solution and 15mg/20g TSE solution. The animals were sacrificed after 24 hours of injection of the solution. Fragments of muscle, kidney and liver were fixed in 10% neutral buffered formalin, and processed for light microscopical studies. The result showed that TSE reduced the histopathological changes induced by the King Cobra venom in the muscles, livers and kidneys and the improvement was proportional to the applied dose of the TSE indicating that tamarind seed extract prevents adverse histological changes in the muscle, liver and kidney.
format	Conference or Workshop Item
author	Al-Ani, Imad Matloub Dally Ismail, Soraya Maung, Khin M. Oothuman, Pakeer
author_facet	Al-Ani, Imad Matloub Dally Ismail, Soraya Maung, Khin M. Oothuman, Pakeer
author_sort	Al-Ani, Imad Matloub Dally
title	The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom
title_short	The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom
title_full	The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom
title_fullStr	The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom
title_full_unstemmed	The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom
title_sort	effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with king cobra venom
publishDate	2015
url	http://irep.iium.edu.my/50960/ http://irep.iium.edu.my/50960/4/Certificate_Nah_Con.jpg http://irep.iium.edu.my/50960/17/50960.pdf
first_indexed	2023-09-18T21:12:07Z
last_indexed	2023-09-18T21:12:07Z
_version_	1777411322451853312

The effects of tamarind seed extract against muscle, liver and renal alterations induced envenomation with King Cobra venom

Similar Items