Gallstones in patients with inherited hemolytic diseases

The purpose is to provide an overview on the incidence of gallstone disease in patients with various types of inherited (chronic) hemolytic diseases at risk of cholelithiasis/choledocholithiasis with particular emphasis on its pathogenesis, genetic, risk factors and management. A detailed electronic...

Full description

Bibliographic Details
Main Authors:	Abdullah, Uday Y.H., M. Jassim, Haitham, A. Baig, Atif, M. Khorsheed, Rana, Al-Khayat, Ali M. H., Sulong, Ahmad Fadzli, Abed, Nagham F., Yassin, Wisam A.
Format:	Article
Language:	English English
Published:	Academic Sciences 2015
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/50805/ http://irep.iium.edu.my/50805/ http://irep.iium.edu.my/50805/1/50805_Gallstones_in_patients_with_inherited_hemolytic_diseases.pdf http://irep.iium.edu.my/50805/4/50805_Gallstones_in_patients_with_inherited_hemolytic_diseases_SCOPUS.pdf

id	iium-50805
recordtype	eprints
spelling	iium-508052017-02-07T06:58:23Z http://irep.iium.edu.my/50805/ Gallstones in patients with inherited hemolytic diseases Abdullah, Uday Y.H. M. Jassim, Haitham A. Baig, Atif M. Khorsheed, Rana Al-Khayat, Ali M. H. Sulong, Ahmad Fadzli Abed, Nagham F. Yassin, Wisam A. R Medicine (General) The purpose is to provide an overview on the incidence of gallstone disease in patients with various types of inherited (chronic) hemolytic diseases at risk of cholelithiasis/choledocholithiasis with particular emphasis on its pathogenesis, genetic, risk factors and management. A detailed electronic literature search to determine the source of materials for this review article was done. The reported incidences of gallstones and choledocholithiasis vary according to the different types of inherited hemolytic diseases and the ethnicity of the studied populations. To date, no review article summarises the incidences of cholelithiasis in patients with various inherited haemolytic diseases was published. Regular ultrasound examination for the presence of gallstones recommended in patients with inherited haemolytic anaemias, particularly those with additional risk factors recommended. Further studies for evaluating the reasons for the higher incidence of cholelithiasis in thalassemia major and sickle cell anemia compared to hereditary spherocytosis; the effect of co inheritance of alpha thalassaemia on decreasing bilirubin level in patients with sickle cell disease and beta thalassaemia; the effect of the co inheritance of UGT1A1 and ABCG8 gene mutation on the incidence of gallstones in other blood diseases such as Hb-H disease, autoimmune haemolytic anaemias, congenital dyserythropoietic anaemia, hereditary elliptocytosis, Southeast Asian Ovalocytosis, glucose-6-phosphate and pyruvate kinase deficiency are recommended. Evaluation of the potential role of the solubility of the mutant proteins and haemoglobin subunit in the red blood cells as an additional mechanism for the development of gallstones in patients with inherited haemolytic anaemias recommended. Academic Sciences 2015 Article PeerReviewed application/pdf en http://irep.iium.edu.my/50805/1/50805_Gallstones_in_patients_with_inherited_hemolytic_diseases.pdf application/pdf en http://irep.iium.edu.my/50805/4/50805_Gallstones_in_patients_with_inherited_hemolytic_diseases_SCOPUS.pdf Abdullah, Uday Y.H. and M. Jassim, Haitham and A. Baig, Atif and M. Khorsheed, Rana and Al-Khayat, Ali M. H. and Sulong, Ahmad Fadzli and Abed, Nagham F. and Yassin, Wisam A. (2015) Gallstones in patients with inherited hemolytic diseases. International Journal of Pharmacy and Pharmaceutical Sciences, 7 (7). pp. 9-15. ISSN 0975-1491 http://innovareacademics.in/journals/index.php/ijpps/article/view/5952
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Abdullah, Uday Y.H. M. Jassim, Haitham A. Baig, Atif M. Khorsheed, Rana Al-Khayat, Ali M. H. Sulong, Ahmad Fadzli Abed, Nagham F. Yassin, Wisam A. Gallstones in patients with inherited hemolytic diseases
description	The purpose is to provide an overview on the incidence of gallstone disease in patients with various types of inherited (chronic) hemolytic diseases at risk of cholelithiasis/choledocholithiasis with particular emphasis on its pathogenesis, genetic, risk factors and management. A detailed electronic literature search to determine the source of materials for this review article was done. The reported incidences of gallstones and choledocholithiasis vary according to the different types of inherited hemolytic diseases and the ethnicity of the studied populations. To date, no review article summarises the incidences of cholelithiasis in patients with various inherited haemolytic diseases was published. Regular ultrasound examination for the presence of gallstones recommended in patients with inherited haemolytic anaemias, particularly those with additional risk factors recommended. Further studies for evaluating the reasons for the higher incidence of cholelithiasis in thalassemia major and sickle cell anemia compared to hereditary spherocytosis; the effect of co inheritance of alpha thalassaemia on decreasing bilirubin level in patients with sickle cell disease and beta thalassaemia; the effect of the co inheritance of UGT1A1 and ABCG8 gene mutation on the incidence of gallstones in other blood diseases such as Hb-H disease, autoimmune haemolytic anaemias, congenital dyserythropoietic anaemia, hereditary elliptocytosis, Southeast Asian Ovalocytosis, glucose-6-phosphate and pyruvate kinase deficiency are recommended. Evaluation of the potential role of the solubility of the mutant proteins and haemoglobin subunit in the red blood cells as an additional mechanism for the development of gallstones in patients with inherited haemolytic anaemias recommended.
format	Article
author	Abdullah, Uday Y.H. M. Jassim, Haitham A. Baig, Atif M. Khorsheed, Rana Al-Khayat, Ali M. H. Sulong, Ahmad Fadzli Abed, Nagham F. Yassin, Wisam A.
author_facet	Abdullah, Uday Y.H. M. Jassim, Haitham A. Baig, Atif M. Khorsheed, Rana Al-Khayat, Ali M. H. Sulong, Ahmad Fadzli Abed, Nagham F. Yassin, Wisam A.
author_sort	Abdullah, Uday Y.H.
title	Gallstones in patients with inherited hemolytic diseases
title_short	Gallstones in patients with inherited hemolytic diseases
title_full	Gallstones in patients with inherited hemolytic diseases
title_fullStr	Gallstones in patients with inherited hemolytic diseases
title_full_unstemmed	Gallstones in patients with inherited hemolytic diseases
title_sort	gallstones in patients with inherited hemolytic diseases
publisher	Academic Sciences
publishDate	2015
url	http://irep.iium.edu.my/50805/ http://irep.iium.edu.my/50805/ http://irep.iium.edu.my/50805/1/50805_Gallstones_in_patients_with_inherited_hemolytic_diseases.pdf http://irep.iium.edu.my/50805/4/50805_Gallstones_in_patients_with_inherited_hemolytic_diseases_SCOPUS.pdf
first_indexed	2023-09-18T21:11:53Z
last_indexed	2023-09-18T21:11:53Z
_version_	1777411307180392448

Gallstones in patients with inherited hemolytic diseases

Similar Items