Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs

A sequential optimization based on statistical design and one-factor-at-a-time (OFAT) method was employed to optimize the media constituents for the improvement of citric acid production from oil palm empty fruit bunches (EFB) through solid state bioconversion using Aspergillus niger IBO-103MNB. The...

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Main Authors:	Bari, Md. Niamul, Alam, Md. Zahangir, Muyibi, Suleyman Aremu, Jamal, Parveen, Al-Mamun, Abdullah
Format:	Article
Language:	English
Published:	Elsevier Science 2009
Subjects:	TP Chemical technology TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/5059/ http://irep.iium.edu.my/5059/ http://irep.iium.edu.my/5059/ http://irep.iium.edu.my/5059/1/Citric-acid-media-original-publisher.pdf

id	iium-5059
recordtype	eprints
spelling	iium-50592011-11-21T02:47:55Z http://irep.iium.edu.my/5059/ Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs Bari, Md. Niamul Alam, Md. Zahangir Muyibi, Suleyman Aremu Jamal, Parveen Al-Mamun, Abdullah TP Chemical technology TP248.13 Biotechnology A sequential optimization based on statistical design and one-factor-at-a-time (OFAT) method was employed to optimize the media constituents for the improvement of citric acid production from oil palm empty fruit bunches (EFB) through solid state bioconversion using Aspergillus niger IBO-103MNB. The results obtained from the Plackett–Burman design indicated that the co-substrate (sucrose), stimulator (methanol) and minerals (Zn, Cu, Mn and Mg) were found to be the major factors for further optimization. Based on the OFAT method, the selected medium constituents and inoculum concentration were optimized by the central composite design (CCD) under the response surface methodology (RSM). The statistical analysis showed that the optimum media containing 6.4% (w/w) of sucrose, 9% (v/w) of minerals and 15.5% (v/w) of inoculum gave the maximum production of citric acid (337.94 g/kg of dry EFB). The analysis showed that sucrose (p < 0.0011) and mineral solution (p < 0.0061) were more significant compared to inoculum concentration (p < 0.0127) for the citric acid production. Elsevier Science 2009 Article PeerReviewed application/pdf en http://irep.iium.edu.my/5059/1/Citric-acid-media-original-publisher.pdf Bari, Md. Niamul and Alam, Md. Zahangir and Muyibi, Suleyman Aremu and Jamal, Parveen and Al-Mamun, Abdullah (2009) Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs. Bioresource Technology, 100 (12). pp. 3113-3120. ISSN 09608524 http://dx.doi.org/10.1016/j.biortech.2009.01.005 doi:10.1016/j.biortech.2009.01.005
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TP Chemical technology TP248.13 Biotechnology
spellingShingle	TP Chemical technology TP248.13 Biotechnology Bari, Md. Niamul Alam, Md. Zahangir Muyibi, Suleyman Aremu Jamal, Parveen Al-Mamun, Abdullah Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs
description	A sequential optimization based on statistical design and one-factor-at-a-time (OFAT) method was employed to optimize the media constituents for the improvement of citric acid production from oil palm empty fruit bunches (EFB) through solid state bioconversion using Aspergillus niger IBO-103MNB. The results obtained from the Plackett–Burman design indicated that the co-substrate (sucrose), stimulator (methanol) and minerals (Zn, Cu, Mn and Mg) were found to be the major factors for further optimization. Based on the OFAT method, the selected medium constituents and inoculum concentration were optimized by the central composite design (CCD) under the response surface methodology (RSM). The statistical analysis showed that the optimum media containing 6.4% (w/w) of sucrose, 9% (v/w) of minerals and 15.5% (v/w) of inoculum gave the maximum production of citric acid (337.94 g/kg of dry EFB). The analysis showed that sucrose (p < 0.0011) and mineral solution (p < 0.0061) were more significant compared to inoculum concentration (p < 0.0127) for the citric acid production.
format	Article
author	Bari, Md. Niamul Alam, Md. Zahangir Muyibi, Suleyman Aremu Jamal, Parveen Al-Mamun, Abdullah
author_facet	Bari, Md. Niamul Alam, Md. Zahangir Muyibi, Suleyman Aremu Jamal, Parveen Al-Mamun, Abdullah
author_sort	Bari, Md. Niamul
title	Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs
title_short	Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs
title_full	Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs
title_fullStr	Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs
title_full_unstemmed	Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs
title_sort	improvement of production of citric acid from oil palm empty fruit bunches: optimization of media by statistical experimental designs
publisher	Elsevier Science
publishDate	2009
url	http://irep.iium.edu.my/5059/ http://irep.iium.edu.my/5059/ http://irep.iium.edu.my/5059/ http://irep.iium.edu.my/5059/1/Citric-acid-media-original-publisher.pdf
first_indexed	2023-09-18T20:13:32Z
last_indexed	2023-09-18T20:13:32Z
_version_	1777407636747059200

Improvement of production of citric acid from oil palm empty fruit bunches: Optimization of media by statistical experimental designs

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