Antimicrobial activity of three hard coral species from South China Sea (Malaysia)

The problem of antimicrobial drug resistance has necessitated a search for new antimicrobial substances from other sources including natural sources. Marine organisms are known to produce metabolites to protect themselves against pathogens and therefore can be considered as a potential source of ant...

Full description

Bibliographic Details
Main Authors:	Qaralleh, Haitham, Idid, Syed Zahir, Saad, Shahbudin, Susanti , Deny, Althunibat, Osama Yousef, Sheikh, Hasan I
Format:	Article
Language:	English
Published:	SYLWAN Journal 2014
Subjects:	QR Microbiology
Online Access:	http://irep.iium.edu.my/50322/ http://irep.iium.edu.my/50322/ http://irep.iium.edu.my/50322/1/coral-article.pdf

id	iium-50322
recordtype	eprints
spelling	iium-503222018-01-08T08:06:04Z http://irep.iium.edu.my/50322/ Antimicrobial activity of three hard coral species from South China Sea (Malaysia) Qaralleh, Haitham Idid, Syed Zahir Saad, Shahbudin Susanti , Deny Althunibat, Osama Yousef Sheikh, Hasan I QR Microbiology The problem of antimicrobial drug resistance has necessitated a search for new antimicrobial substances from other sources including natural sources. Marine organisms are known to produce metabolites to protect themselves against pathogens and therefore can be considered as a potential source of antimicrobial substances. This study designed to evaluate the antimicrobial activity of three hard coral species namely Favites sp Link (Faviidae), Galaxea fascicularis Linnaeus (Oculinidae), and Galaxea astreata Lamarck (Oculinidae) against six pathogenic microbes. The coral species were extracted with water and a combination of dichloromethane and methanol. The antimicrobial activity of the extracts was evaluated using disc diffusion method and microdilution method. From the disc diffusion method, the organic extracts showed antimicrobial activity while the aqueous extracts showed no activity. The organic extract from G. fascicularis was the most effective against Staphylococcus aureus (11 mm) and Bacillus cereus (10.5 mm). From the microdilution method, the organic extracts of G. fascicularis and G. astreata showed inhibitory effect against S. aureus and B. cereus at low concentrations (0.003 - 0.1 mg/mL). However, complete growth inhibitions of S. aureus and B.cereus were observed for the organic extract of G. fascicularis at concentrations of 0.34 and 1.1 mg/mL, respectively. Further studies must be conducted to isolate the antimicrobial compounds from the G. fascicularis, which may contribute towards finding compounds for the treatment of infectious diseases. SYLWAN Journal 2014 Article PeerReviewed application/pdf en cc_by http://irep.iium.edu.my/50322/1/coral-article.pdf Qaralleh, Haitham and Idid, Syed Zahir and Saad, Shahbudin and Susanti , Deny and Althunibat, Osama Yousef and Sheikh, Hasan I (2014) Antimicrobial activity of three hard coral species from South China Sea (Malaysia). SYLWAN Journal, 158 (4). pp. 20-25. ISSN 0039-7660 http://sylwan.ibles.org/index.html
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QR Microbiology
spellingShingle	QR Microbiology Qaralleh, Haitham Idid, Syed Zahir Saad, Shahbudin Susanti , Deny Althunibat, Osama Yousef Sheikh, Hasan I Antimicrobial activity of three hard coral species from South China Sea (Malaysia)
description	The problem of antimicrobial drug resistance has necessitated a search for new antimicrobial substances from other sources including natural sources. Marine organisms are known to produce metabolites to protect themselves against pathogens and therefore can be considered as a potential source of antimicrobial substances. This study designed to evaluate the antimicrobial activity of three hard coral species namely Favites sp Link (Faviidae), Galaxea fascicularis Linnaeus (Oculinidae), and Galaxea astreata Lamarck (Oculinidae) against six pathogenic microbes. The coral species were extracted with water and a combination of dichloromethane and methanol. The antimicrobial activity of the extracts was evaluated using disc diffusion method and microdilution method. From the disc diffusion method, the organic extracts showed antimicrobial activity while the aqueous extracts showed no activity. The organic extract from G. fascicularis was the most effective against Staphylococcus aureus (11 mm) and Bacillus cereus (10.5 mm). From the microdilution method, the organic extracts of G. fascicularis and G. astreata showed inhibitory effect against S. aureus and B. cereus at low concentrations (0.003 - 0.1 mg/mL). However, complete growth inhibitions of S. aureus and B.cereus were observed for the organic extract of G. fascicularis at concentrations of 0.34 and 1.1 mg/mL, respectively. Further studies must be conducted to isolate the antimicrobial compounds from the G. fascicularis, which may contribute towards finding compounds for the treatment of infectious diseases.
format	Article
author	Qaralleh, Haitham Idid, Syed Zahir Saad, Shahbudin Susanti , Deny Althunibat, Osama Yousef Sheikh, Hasan I
author_facet	Qaralleh, Haitham Idid, Syed Zahir Saad, Shahbudin Susanti , Deny Althunibat, Osama Yousef Sheikh, Hasan I
author_sort	Qaralleh, Haitham
title	Antimicrobial activity of three hard coral species from South China Sea (Malaysia)
title_short	Antimicrobial activity of three hard coral species from South China Sea (Malaysia)
title_full	Antimicrobial activity of three hard coral species from South China Sea (Malaysia)
title_fullStr	Antimicrobial activity of three hard coral species from South China Sea (Malaysia)
title_full_unstemmed	Antimicrobial activity of three hard coral species from South China Sea (Malaysia)
title_sort	antimicrobial activity of three hard coral species from south china sea (malaysia)
publisher	SYLWAN Journal
publishDate	2014
url	http://irep.iium.edu.my/50322/ http://irep.iium.edu.my/50322/ http://irep.iium.edu.my/50322/1/coral-article.pdf
first_indexed	2023-09-18T21:11:07Z
last_indexed	2023-09-18T21:11:07Z
_version_	1777411259596013568

Antimicrobial activity of three hard coral species from South China Sea (Malaysia)

Similar Items