Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus

Cerebral angioinvasive aspergillosis is a rare manifestation of disseminated aspergillosis which may result in stroke in immunocompromised individuals. Reports of such disease in patients with diabetes mellitus are rare. We describe a 45-year-old man with diabetes mellitus who presented with a three...

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Main Authors:	Mohamed Ibrahim, Norlinah, Ngow, Harris Abdullah, BB, Hamidon
Format:	Article
Language:	English
Published:	Singapore Medical Association 2007
Subjects:	R Medicine (General) RB Pathology
Online Access:	http://irep.iium.edu.my/5000/ http://irep.iium.edu.my/5000/ http://irep.iium.edu.my/5000/1/4801cr1.pdf

id	iium-5000
recordtype	eprints
spelling	iium-50002013-06-10T03:34:51Z http://irep.iium.edu.my/5000/ Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus Mohamed Ibrahim, Norlinah Ngow, Harris Abdullah BB, Hamidon R Medicine (General) RB Pathology Cerebral angioinvasive aspergillosis is a rare manifestation of disseminated aspergillosis which may result in stroke in immunocompromised individuals. Reports of such disease in patients with diabetes mellitus are rare. We describe a 45-year-old man with diabetes mellitus who presented with a three-day history of right-sided limb weakness and aphasia. Cerebral computed tomography showed features of an acute infarct involving the left anterior and middle cerebral arteries. He was initially treated for an acute ischaemic stroke. Further history revealed that he was investigated for a growth in the sphenoid sinus two months earlier. Culture of the biopsied material from the sphenoid sinus grew Aspergillus fumigatus. Magnetic resonance imaging showed an extension of the growth to the brain, causing the acute ischaemic stroke. He was subsequently diagnosed with angioinvasive cerebral aspergillosis and was commenced on intravenous amphotericin B. Unfortunately, he succumbed to his illness despite treatment. Singapore Medical Association 2007 Article PeerReviewed application/pdf en http://irep.iium.edu.my/5000/1/4801cr1.pdf Mohamed Ibrahim, Norlinah and Ngow, Harris Abdullah and BB, Hamidon (2007) Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus. Singapore Medical Journal, 48 (1). e1-4. ISSN 0037-5675 http://www.sma.org.sg/smj/4801/4801cr1.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General) RB Pathology
spellingShingle	R Medicine (General) RB Pathology Mohamed Ibrahim, Norlinah Ngow, Harris Abdullah BB, Hamidon Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
description	Cerebral angioinvasive aspergillosis is a rare manifestation of disseminated aspergillosis which may result in stroke in immunocompromised individuals. Reports of such disease in patients with diabetes mellitus are rare. We describe a 45-year-old man with diabetes mellitus who presented with a three-day history of right-sided limb weakness and aphasia. Cerebral computed tomography showed features of an acute infarct involving the left anterior and middle cerebral arteries. He was initially treated for an acute ischaemic stroke. Further history revealed that he was investigated for a growth in the sphenoid sinus two months earlier. Culture of the biopsied material from the sphenoid sinus grew Aspergillus fumigatus. Magnetic resonance imaging showed an extension of the growth to the brain, causing the acute ischaemic stroke. He was subsequently diagnosed with angioinvasive cerebral aspergillosis and was commenced on intravenous amphotericin B. Unfortunately, he succumbed to his illness despite treatment.
format	Article
author	Mohamed Ibrahim, Norlinah Ngow, Harris Abdullah BB, Hamidon
author_facet	Mohamed Ibrahim, Norlinah Ngow, Harris Abdullah BB, Hamidon
author_sort	Mohamed Ibrahim, Norlinah
title	Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_short	Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_full	Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_fullStr	Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_full_unstemmed	Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_sort	angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
publisher	Singapore Medical Association
publishDate	2007
url	http://irep.iium.edu.my/5000/ http://irep.iium.edu.my/5000/ http://irep.iium.edu.my/5000/1/4801cr1.pdf
first_indexed	2023-09-18T20:13:27Z
last_indexed	2023-09-18T20:13:27Z
_version_	1777407630772273152

Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus

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