Effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in Tc-99m SPECT

In SPECT, noise is one of the major limitations that degrade image quality. To suppress the noisy signals in an image, digital filters are most commonly applied. However, in SPECT image recon-struction, selection of an appropriate filter and its functions has always remained a difficult task. In thi...

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Main Authors: Sayed, Inayatullah Shah, Mohamed Nasrudin, Nor Syahirah
Format: Article
Language:English
Published: Scientific Research Publishing 2016
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Online Access:http://irep.iium.edu.my/49979/
http://irep.iium.edu.my/49979/
http://irep.iium.edu.my/49979/
http://irep.iium.edu.my/49979/1/IJMPCERO_2016_BWFilter.pdf
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spelling iium-499792016-10-12T09:55:27Z http://irep.iium.edu.my/49979/ Effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in Tc-99m SPECT Sayed, Inayatullah Shah Mohamed Nasrudin, Nor Syahirah QC Physics In SPECT, noise is one of the major limitations that degrade image quality. To suppress the noisy signals in an image, digital filters are most commonly applied. However, in SPECT image recon-struction, selection of an appropriate filter and its functions has always remained a difficult task. In this work an attempt was made to investigate the effects of varying cut-off frequencies and in keeping the order of Butterworth filter constant on detectability and contrast of hot and cold re-gions images. A new insert simulating hot and cold regions which provides similar views in a re-constructed image was placed in the phantom’s cylindrical source tank and imaged. Tc-99m ra-dionuclide was distributed uniformly in the phantom. SPECT data were collected in a 20% energy window centered at 140 keV by a Philips ADAC Forte dual head gamma camera mounted with a LEHR collimator. Images were generated by using the filtered backprojection technique. A But-terworth filter of order 5 with cut-off frequencies 0.35 and 0.45 cycles.cm-1 was applied. Images were examined in terms of hot and cold regions, detectability and contrast. Results show that the hot and cold regions’ detectability and contrast vary with the change of cut-off frequency. With a 0.45 cycles.cm-1 cut-off frequency a significant enhancement in contrast of cold regions was achieved as compared to a 0.35 cycles.cm-1 cut-off frequency. Furthermore, the detectability of hot and cold regions improved with the use of a 0.45 cycles.cm-1 cut-off frequency. In conclusion, image quality of hot and cold regions affected in a different way with a change of cut-off frequency. Thus, care should be taken in selecting the filter cut-off frequency prior to reconstruction of images; particularly, when both types of regions are expected in the reconstructed image. Scientific Research Publishing 2016-02 Article PeerReviewed application/pdf en http://irep.iium.edu.my/49979/1/IJMPCERO_2016_BWFilter.pdf Sayed, Inayatullah Shah and Mohamed Nasrudin, Nor Syahirah (2016) Effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in Tc-99m SPECT. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, 5 (1). pp. 100-109. ISSN 2168-5436 E-ISSN 2168-5444 http://www.scirp.org/journal/ijmpcero http://dx.doi.org/10.4236/ijmpcero.2016.51011
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic QC Physics
spellingShingle QC Physics
Sayed, Inayatullah Shah
Mohamed Nasrudin, Nor Syahirah
Effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in Tc-99m SPECT
description In SPECT, noise is one of the major limitations that degrade image quality. To suppress the noisy signals in an image, digital filters are most commonly applied. However, in SPECT image recon-struction, selection of an appropriate filter and its functions has always remained a difficult task. In this work an attempt was made to investigate the effects of varying cut-off frequencies and in keeping the order of Butterworth filter constant on detectability and contrast of hot and cold re-gions images. A new insert simulating hot and cold regions which provides similar views in a re-constructed image was placed in the phantom’s cylindrical source tank and imaged. Tc-99m ra-dionuclide was distributed uniformly in the phantom. SPECT data were collected in a 20% energy window centered at 140 keV by a Philips ADAC Forte dual head gamma camera mounted with a LEHR collimator. Images were generated by using the filtered backprojection technique. A But-terworth filter of order 5 with cut-off frequencies 0.35 and 0.45 cycles.cm-1 was applied. Images were examined in terms of hot and cold regions, detectability and contrast. Results show that the hot and cold regions’ detectability and contrast vary with the change of cut-off frequency. With a 0.45 cycles.cm-1 cut-off frequency a significant enhancement in contrast of cold regions was achieved as compared to a 0.35 cycles.cm-1 cut-off frequency. Furthermore, the detectability of hot and cold regions improved with the use of a 0.45 cycles.cm-1 cut-off frequency. In conclusion, image quality of hot and cold regions affected in a different way with a change of cut-off frequency. Thus, care should be taken in selecting the filter cut-off frequency prior to reconstruction of images; particularly, when both types of regions are expected in the reconstructed image.
format Article
author Sayed, Inayatullah Shah
Mohamed Nasrudin, Nor Syahirah
author_facet Sayed, Inayatullah Shah
Mohamed Nasrudin, Nor Syahirah
author_sort Sayed, Inayatullah Shah
title Effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in Tc-99m SPECT
title_short Effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in Tc-99m SPECT
title_full Effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in Tc-99m SPECT
title_fullStr Effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in Tc-99m SPECT
title_full_unstemmed Effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in Tc-99m SPECT
title_sort effect of cut-off frequency of butterworth filter on detectability and contrast of hot and cold regions in tc-99m spect
publisher Scientific Research Publishing
publishDate 2016
url http://irep.iium.edu.my/49979/
http://irep.iium.edu.my/49979/
http://irep.iium.edu.my/49979/
http://irep.iium.edu.my/49979/1/IJMPCERO_2016_BWFilter.pdf
first_indexed 2023-09-18T21:10:37Z
last_indexed 2023-09-18T21:10:37Z
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