Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient
Histoplasmosis usually affects immunocompromised patients. Histoplasmosis infiltration to the adrenal in an immunocompetent host is rare, more so those who presented with adrenal insufficiency. We report a case of 54-year-old previously fit and healthy man who presented with chronic headache of tw...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ministry of Health and Universiti Brunei Darussalem
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/49649/ http://irep.iium.edu.my/49649/ http://irep.iium.edu.my/49649/1/Bimj2015115261.pdf |
| Summary: | Histoplasmosis usually affects immunocompromised patients. Histoplasmosis infiltration to the adrenal
in an immunocompetent host is rare, more so those who presented with adrenal insufficiency. We report
a case of 54-year-old previously fit and healthy man who presented with chronic headache of two
months duration that was associated with loss of appetite and weight-loss. He had hypotension, hyponatremia,
relative hyperkalemia with morning cortisol of 160 nmol/L. Computed tomography of the
adrenals showed bilateral enlarged adrenal glands and biopsy confirmed histoplasmosis infiltration.
Treatment successfully ameliorate symptoms of hypocortisolism. This case illustrates that immunocompetent
patient is still susceptible to adrenal histoplasmosis resulting in adrenal insufficiency.
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