The effect of Nigella sativa extract on mouse oocyte activation

Female infertility cases have been increased worldwide by several factors including lifestyle. Nigella sativa is a well-known medicinal plant which has been used globally for prevention and cure of many diseases. Nigella sativa with its active components were thought to be a solution for the inferti...

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Main Authors:	Abdul Rahman, Suzanah, Enseri, Mohd Qairul Amir, Abdul Samat, Nadia Hanis
Format:	Conference or Workshop Item
Language:	English
Published:	2014
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/49398/ http://irep.iium.edu.my/49398/ http://irep.iium.edu.my/49398/1/49398.pdf

id	iium-49398
recordtype	eprints
spelling	iium-493982016-05-12T01:34:19Z http://irep.iium.edu.my/49398/ The effect of Nigella sativa extract on mouse oocyte activation Abdul Rahman, Suzanah Enseri, Mohd Qairul Amir Abdul Samat, Nadia Hanis RM Therapeutics. Pharmacology Female infertility cases have been increased worldwide by several factors including lifestyle. Nigella sativa is a well-known medicinal plant which has been used globally for prevention and cure of many diseases. Nigella sativa with its active components were thought to be a solution for the infertility problem. Thus in this experiment, the effects of Nigella sativa on the number of oocytes and number of fertilized oocytes were investigated. This was carried out by treating 20 Balb/c female mice divided equally into groups of four; i) control group (no treatment given), ii) treated with 25mg/kg per body weight of Nigella sativa, iii) treated with 50mg/kg per body weight of Nigella sativa, and iv) treated with 75mg/kg per body weight of Nigella sativa. The treatments were given daily for five days (estrous cycle) via intraperitoneal (i.p.) injection. Then, they were sacrificed and oocytes were obtained, followed by in vitro fertilization process. Total number of oocytes obtained was calculated and total number of fertilized oocytes was recorded. This study discovered that Nigella sativa supplementation did not indicate any significant difference (p>0.05) in the effect of different doses of Nigella sativa with total number of oocytes produced as well as the total number of fertilized oocytes. It was concluded that Nigella sativa did not increase the number of oocytes and the number of fertilized oocytes produced in mice. 2014 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/49398/1/49398.pdf Abdul Rahman, Suzanah and Enseri, Mohd Qairul Amir and Abdul Samat, Nadia Hanis (2014) The effect of Nigella sativa extract on mouse oocyte activation. In: International Health Conference IIUM (IHCI 2014), 3rd-4th Dec. 2014, Kuantan, Pahang. (Unpublished) http://www.iium.edu.my/ihci/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Abdul Rahman, Suzanah Enseri, Mohd Qairul Amir Abdul Samat, Nadia Hanis The effect of Nigella sativa extract on mouse oocyte activation
description	Female infertility cases have been increased worldwide by several factors including lifestyle. Nigella sativa is a well-known medicinal plant which has been used globally for prevention and cure of many diseases. Nigella sativa with its active components were thought to be a solution for the infertility problem. Thus in this experiment, the effects of Nigella sativa on the number of oocytes and number of fertilized oocytes were investigated. This was carried out by treating 20 Balb/c female mice divided equally into groups of four; i) control group (no treatment given), ii) treated with 25mg/kg per body weight of Nigella sativa, iii) treated with 50mg/kg per body weight of Nigella sativa, and iv) treated with 75mg/kg per body weight of Nigella sativa. The treatments were given daily for five days (estrous cycle) via intraperitoneal (i.p.) injection. Then, they were sacrificed and oocytes were obtained, followed by in vitro fertilization process. Total number of oocytes obtained was calculated and total number of fertilized oocytes was recorded. This study discovered that Nigella sativa supplementation did not indicate any significant difference (p>0.05) in the effect of different doses of Nigella sativa with total number of oocytes produced as well as the total number of fertilized oocytes. It was concluded that Nigella sativa did not increase the number of oocytes and the number of fertilized oocytes produced in mice.
format	Conference or Workshop Item
author	Abdul Rahman, Suzanah Enseri, Mohd Qairul Amir Abdul Samat, Nadia Hanis
author_facet	Abdul Rahman, Suzanah Enseri, Mohd Qairul Amir Abdul Samat, Nadia Hanis
author_sort	Abdul Rahman, Suzanah
title	The effect of Nigella sativa extract on mouse oocyte activation
title_short	The effect of Nigella sativa extract on mouse oocyte activation
title_full	The effect of Nigella sativa extract on mouse oocyte activation
title_fullStr	The effect of Nigella sativa extract on mouse oocyte activation
title_full_unstemmed	The effect of Nigella sativa extract on mouse oocyte activation
title_sort	effect of nigella sativa extract on mouse oocyte activation
publishDate	2014
url	http://irep.iium.edu.my/49398/ http://irep.iium.edu.my/49398/ http://irep.iium.edu.my/49398/1/49398.pdf
first_indexed	2023-09-18T21:09:51Z
last_indexed	2023-09-18T21:09:51Z
_version_	1777411179545624576

The effect of Nigella sativa extract on mouse oocyte activation

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