Application of group-based QSAR and molecular docking in the design of insulin-like growth factor antagonists
Purpose: To identify the structural requirements for designing a lead key for insulin-like growth factor (IGF-1R) inhibition using group-based quantitative structure activity relationship (GQSAR) and molecular docking. Methods: GQSAR method requires fragmentation of molecules. The molecules in the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Pharmacotherapy Group
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/49051/ http://irep.iium.edu.my/49051/ http://irep.iium.edu.my/49051/ http://irep.iium.edu.my/49051/1/Application_of_Group-Based_QSAR_and_Molecular_Docking_in_the_Design_of_Insulin-Like_Growth_Factor_Antagonists.pdf http://irep.iium.edu.my/49051/4/49051_Application%20of%20group-based%20QSAR%20and%20molecular_SCOPUS.pdf |