Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms

The aim of the study was to investigate the antimicrobial activity of Nuclea subdita (Korth) Steud against six pathogenic microorganisms. Methodology and results: Young and maturedtrees ao N. subdita were cut and separated into bark and wood parts, respectively, prior to extraction process. Phytoche...

Full description

Bibliographic Details
Main Authors:	Jamaluddin, Fatin Ruzanna, Lee, Seng Hua, Ashaari, Zaidon, Wahab, Razak, Mohd Daud, Jamaluddin
Format:	Article
Language:	English
Published:	Malaysian Society for Microbiology 2015
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/48495/ http://irep.iium.edu.my/48495/ http://irep.iium.edu.my/48495/1/Paper_Antimicrobial_Nauclea_subdita_6-Vol_11-4-MJM_720-15_%28FINAL%29_Dec_2015.pdf

id	iium-48495
recordtype	eprints
spelling	iium-484952016-12-19T07:55:20Z http://irep.iium.edu.my/48495/ Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms Jamaluddin, Fatin Ruzanna Lee, Seng Hua Ashaari, Zaidon Wahab, Razak Mohd Daud, Jamaluddin Q Science (General) The aim of the study was to investigate the antimicrobial activity of Nuclea subdita (Korth) Steud against six pathogenic microorganisms. Methodology and results: Young and maturedtrees ao N. subdita were cut and separated into bark and wood parts, respectively, prior to extraction process. Phytochemical screening tests, antimicrobial activity, minimal inhibitory concentration (MIC) and minimal bacterial concentration (MBC) values were determined. Preliminary screening for phytochemical components showed that both young and matured tree had similar constituents. Extracts from matured tree showed more potency in terms of the zones of inhibition sizes than the young tree. Extract of N. subdita was more potent to both marine bacteria, Vibrio parahaemoliticus and V. alginolyticus, while Candida albican and Aspergillus niger were resistant to it. The sensitivity test showed that 500 ug/mL is the optimum concentration for extract of bottom sapwood of mature tree to act as bactericidal. Conclusion, significance and impact study: The results from this study suggest that N. subdita bark and wood extracts may serve as potential source of antimicrobial agents for future development in medicine applications. Malaysian Society for Microbiology 2015 Article PeerReviewed application/pdf en http://irep.iium.edu.my/48495/1/Paper_Antimicrobial_Nauclea_subdita_6-Vol_11-4-MJM_720-15_%28FINAL%29_Dec_2015.pdf Jamaluddin, Fatin Ruzanna and Lee, Seng Hua and Ashaari, Zaidon and Wahab, Razak and Mohd Daud, Jamaluddin (2015) Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms. Malaysian Journal of Microbiolog, 11 (4). pp. 365-372. ISSN 1823-8262 http://web.usm.my/mjm
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General)
spellingShingle	Q Science (General) Jamaluddin, Fatin Ruzanna Lee, Seng Hua Ashaari, Zaidon Wahab, Razak Mohd Daud, Jamaluddin Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
description	The aim of the study was to investigate the antimicrobial activity of Nuclea subdita (Korth) Steud against six pathogenic microorganisms. Methodology and results: Young and maturedtrees ao N. subdita were cut and separated into bark and wood parts, respectively, prior to extraction process. Phytochemical screening tests, antimicrobial activity, minimal inhibitory concentration (MIC) and minimal bacterial concentration (MBC) values were determined. Preliminary screening for phytochemical components showed that both young and matured tree had similar constituents. Extracts from matured tree showed more potency in terms of the zones of inhibition sizes than the young tree. Extract of N. subdita was more potent to both marine bacteria, Vibrio parahaemoliticus and V. alginolyticus, while Candida albican and Aspergillus niger were resistant to it. The sensitivity test showed that 500 ug/mL is the optimum concentration for extract of bottom sapwood of mature tree to act as bactericidal. Conclusion, significance and impact study: The results from this study suggest that N. subdita bark and wood extracts may serve as potential source of antimicrobial agents for future development in medicine applications.
format	Article
author	Jamaluddin, Fatin Ruzanna Lee, Seng Hua Ashaari, Zaidon Wahab, Razak Mohd Daud, Jamaluddin
author_facet	Jamaluddin, Fatin Ruzanna Lee, Seng Hua Ashaari, Zaidon Wahab, Razak Mohd Daud, Jamaluddin
author_sort	Jamaluddin, Fatin Ruzanna
title	Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_short	Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_full	Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_fullStr	Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_full_unstemmed	Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_sort	antimicrobial activities of stembark and wood extracts from nuclea subdita against pathogenic microorganisms
publisher	Malaysian Society for Microbiology
publishDate	2015
url	http://irep.iium.edu.my/48495/ http://irep.iium.edu.my/48495/ http://irep.iium.edu.my/48495/1/Paper_Antimicrobial_Nauclea_subdita_6-Vol_11-4-MJM_720-15_%28FINAL%29_Dec_2015.pdf
first_indexed	2023-09-18T21:08:47Z
last_indexed	2023-09-18T21:08:47Z
_version_	1777411111979581440

Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms

Similar Items