Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats

Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats

Syzygium polyanthum (Wight) Walp. var. polyanthum leaves are consumed as a traditional Malay treatment of hypertension. This study investigates hypotensive potential of aqueous (AESP) and residual methanolic (met-AESP) extracts of S. polyanthum leaves and possible involvement of autonomic receptors....

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Main Authors: Ismail, Azlini, Mohamed, M., Sulaiman, Siti Amrah, Wan Ahmad, W. A. N.
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2013
Subjects:
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Online Access:http://irep.iium.edu.my/48151/
http://irep.iium.edu.my/48151/
http://irep.iium.edu.my/48151/
http://irep.iium.edu.my/48151/1/716532.pdf
id iium-48151
recordtype eprints
spelling iium-481512016-07-15T06:18:14Z http://irep.iium.edu.my/48151/ Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats Ismail, Azlini Mohamed, M. Sulaiman, Siti Amrah Wan Ahmad, W. A. N. RM Therapeutics. Pharmacology RS Pharmacy and materia medica Syzygium polyanthum (Wight) Walp. var. polyanthum leaves are consumed as a traditional Malay treatment of hypertension. This study investigates hypotensive potential of aqueous (AESP) and residual methanolic (met-AESP) extracts of S. polyanthum leaves and possible involvement of autonomic receptors. AESP and met-AESP (20 to 100 mg/kg) were intravenously administered into anaesthetized Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) rats. Blood pressure and heart were monitored for 20 min. AESP and met-AESP induced significant dose-dependent hypotension, but only 100 mg/kg AESP caused mild bradycardia ( Hindawi Publishing Corporation 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/48151/1/716532.pdf Ismail, Azlini and Mohamed, M. and Sulaiman, Siti Amrah and Wan Ahmad, W. A. N. (2013) Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats. Evidence-Based Complementary and Alternative Medicine, 2013. pp. 1-16. ISSN 1741-427X E-ISSN 1741-4288 http://dx.doi.org/10.1155/2013/716532 10.1155/2013/716532
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
spellingShingle RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Ismail, Azlini
Mohamed, M.
Sulaiman, Siti Amrah
Wan Ahmad, W. A. N.
Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats
description Syzygium polyanthum (Wight) Walp. var. polyanthum leaves are consumed as a traditional Malay treatment of hypertension. This study investigates hypotensive potential of aqueous (AESP) and residual methanolic (met-AESP) extracts of S. polyanthum leaves and possible involvement of autonomic receptors. AESP and met-AESP (20 to 100 mg/kg) were intravenously administered into anaesthetized Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) rats. Blood pressure and heart were monitored for 20 min. AESP and met-AESP induced significant dose-dependent hypotension, but only 100 mg/kg AESP caused mild bradycardia (
format Article
author Ismail, Azlini
Mohamed, M.
Sulaiman, Siti Amrah
Wan Ahmad, W. A. N.
author_facet Ismail, Azlini
Mohamed, M.
Sulaiman, Siti Amrah
Wan Ahmad, W. A. N.
author_sort Ismail, Azlini
title Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats
title_short Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats
title_full Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats
title_fullStr Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats
title_full_unstemmed Autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of Syzygium polyanthum(Wight) Walp.var.polyanthum leaves in anaesthetized rats
title_sort autonomic nervous system mediates the hypotensive effects of aqueous and residual methanolic extracts of syzygium polyanthum(wight) walp.var.polyanthum leaves in anaesthetized rats
publisher Hindawi Publishing Corporation
publishDate 2013
url http://irep.iium.edu.my/48151/
http://irep.iium.edu.my/48151/
http://irep.iium.edu.my/48151/
http://irep.iium.edu.my/48151/1/716532.pdf
first_indexed 2023-09-18T21:08:22Z
last_indexed 2023-09-18T21:08:22Z
_version_ 1777411086320926720

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