Thioguanine-based DENV-2 NS2B/NS3 protease inhibitors: Virtual screening, synthesis, biological evaluation and molecular modelling
Dengue virus Type 2 (DENV-2) is predominant serotype causing major dengue epidemics. There are a number of studies carried out to find its effective antiviral, however to date, there is still no molecule either from peptide or small molecules released as a drug. The present study aims to identify sm...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
Public Library of Science
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/47962/ http://irep.iium.edu.my/47962/ http://irep.iium.edu.my/47962/ http://irep.iium.edu.my/47962/1/47962_Thioguanine-based%20DENV-2%20NS2B-NS3.pdf http://irep.iium.edu.my/47962/2/47962_Thioguanine-based%20DENV-2%20NS2B-NS3_SCOPUS.pdf http://irep.iium.edu.my/47962/3/47962_Thioguanine-based%20DENV-2%20NS2B-NS3_WOS.pdf |