Antioxidant and antibacterial activities of ruta angustifolia extract

Ruta angustifolia was used in this study in order to evaluate the antimicrobial activity and antioxidant properties and its correlation with the polyphenolic content. Two Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 11778) and two Gram–negative bacteria (Pseudomonas...

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Main Authors:	Shuib, Nur Azra, Sulaiman, Fatimatul Akmal, Razak , Izzatie, Darnis, Deny Susanti
Format:	Article
Language:	English
Published:	Universiti Teknologi Malaysia 2015
Online Access:	http://irep.iium.edu.my/47395/ http://irep.iium.edu.my/47395/ http://irep.iium.edu.my/47395/ http://irep.iium.edu.my/47395/1/6747-18528-1-SM.pdf

id	iium-47395
recordtype	eprints
spelling	iium-473952018-05-22T03:23:29Z http://irep.iium.edu.my/47395/ Antioxidant and antibacterial activities of ruta angustifolia extract Shuib, Nur Azra Sulaiman, Fatimatul Akmal Razak , Izzatie Darnis, Deny Susanti Ruta angustifolia was used in this study in order to evaluate the antimicrobial activity and antioxidant properties and its correlation with the polyphenolic content. Two Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 11778) and two Gram–negative bacteria (Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 8739) were used to determine the antibacterial activity. Aqueous maceration extract was used for antioxidant activities and methanolic maceration extract was used for antibacterial activity. The antioxidant properties and activities were evaluated by using total phenolic content (TPC), total flavonoid content (TFC), DPPH free radical scavenging activity and beta-carotene bleaching method. Whereas, the antibacterial activity was examined using disc diffusion method against selected microorganism at concentration 1.0 mg/disc. The results showed the phenolic content of R. angustifolia extract was 18.89 g GAE/100 g extract while the flavonoid content was 14.170 g QE/100 g extract. R. angustifolia exhibited good radical scavenging with IC50 value of 2.04 mg/ml. The result for disc diffusion method showed no inhibition zone against all the strains of bacteria at 1.0 mg/disc concentration of the extract. Based on the results, it can be concluded that the R. angustifolia aqueous extract has the antioxidant properties and there is correlation between polyphenolic content of the extract with its antioxidant activity. However, R. angustifolia methanolic extract did not show any antibacterial activity. Universiti Teknologi Malaysia 2015 Article PeerReviewed application/pdf en http://irep.iium.edu.my/47395/1/6747-18528-1-SM.pdf Shuib, Nur Azra and Sulaiman, Fatimatul Akmal and Razak , Izzatie and Darnis, Deny Susanti (2015) Antioxidant and antibacterial activities of ruta angustifolia extract. Jurnal Teknologi, 77 (25). pp. 101-105. ISSN 0127–9696 E-ISSN 2180–3722 http://www.jurnalteknologi.utm.my/index.php/jurnalteknologi/article/view/6747 http://dx.doi.org/10.11113/jt.v77.6747
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
description	Ruta angustifolia was used in this study in order to evaluate the antimicrobial activity and antioxidant properties and its correlation with the polyphenolic content. Two Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 11778) and two Gram–negative bacteria (Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 8739) were used to determine the antibacterial activity. Aqueous maceration extract was used for antioxidant activities and methanolic maceration extract was used for antibacterial activity. The antioxidant properties and activities were evaluated by using total phenolic content (TPC), total flavonoid content (TFC), DPPH free radical scavenging activity and beta-carotene bleaching method. Whereas, the antibacterial activity was examined using disc diffusion method against selected microorganism at concentration 1.0 mg/disc. The results showed the phenolic content of R. angustifolia extract was 18.89 g GAE/100 g extract while the flavonoid content was 14.170 g QE/100 g extract. R. angustifolia exhibited good radical scavenging with IC50 value of 2.04 mg/ml. The result for disc diffusion method showed no inhibition zone against all the strains of bacteria at 1.0 mg/disc concentration of the extract. Based on the results, it can be concluded that the R. angustifolia aqueous extract has the antioxidant properties and there is correlation between polyphenolic content of the extract with its antioxidant activity. However, R. angustifolia methanolic extract did not show any antibacterial activity.
format	Article
author	Shuib, Nur Azra Sulaiman, Fatimatul Akmal Razak , Izzatie Darnis, Deny Susanti
spellingShingle	Shuib, Nur Azra Sulaiman, Fatimatul Akmal Razak , Izzatie Darnis, Deny Susanti Antioxidant and antibacterial activities of ruta angustifolia extract
author_facet	Shuib, Nur Azra Sulaiman, Fatimatul Akmal Razak , Izzatie Darnis, Deny Susanti
author_sort	Shuib, Nur Azra
title	Antioxidant and antibacterial activities of ruta angustifolia extract
title_short	Antioxidant and antibacterial activities of ruta angustifolia extract
title_full	Antioxidant and antibacterial activities of ruta angustifolia extract
title_fullStr	Antioxidant and antibacterial activities of ruta angustifolia extract
title_full_unstemmed	Antioxidant and antibacterial activities of ruta angustifolia extract
title_sort	antioxidant and antibacterial activities of ruta angustifolia extract
publisher	Universiti Teknologi Malaysia
publishDate	2015
url	http://irep.iium.edu.my/47395/ http://irep.iium.edu.my/47395/ http://irep.iium.edu.my/47395/ http://irep.iium.edu.my/47395/1/6747-18528-1-SM.pdf
first_indexed	2023-09-18T21:07:27Z
last_indexed	2023-09-18T21:07:27Z
_version_	1777411028376616960

Antioxidant and antibacterial activities of ruta angustifolia extract

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