Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells

Lack of effective tools to diagnose lung cancer at an early stage has caused high mortality in cancer patients especially in lung cancer patients. Electronic nose (E-Nose) technology is believed to offer non-invasive, rapid and reliable analytic approach by measuring the odour released from can...

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Main Authors:	Thriumani, Reena, Zakaria, Ammar, Jeffree, Amanina Iymia, Hishamuddin, N.A., Omar, Mohammad Iqbal, Adom, Abdul Hamid, Shakaff, Ali Yeon, Kamarudin, Latifah Munirah, Yusuf, Nurlisa, Hashim, Yumi Zuhanis Has-Yun, Mohamed Helmy, Khaled
Format:	Conference or Workshop Item
Language:	English English
Published:	2014
Subjects:	Q Science (General) RC Internal medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) TA213 Engineering machinery, tools, and implements
Online Access:	http://irep.iium.edu.my/47328/ http://irep.iium.edu.my/47328/ http://irep.iium.edu.my/47328/4/47328.pdf http://irep.iium.edu.my/47328/7/47328_Cancer%20detection%20using%20an%20electronic%20nose_Scopus.pdf

id	iium-47328
recordtype	eprints
spelling	iium-473282017-09-25T03:53:07Z http://irep.iium.edu.my/47328/ Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells Thriumani, Reena Zakaria, Ammar Jeffree, Amanina Iymia Hishamuddin, N.A. Omar, Mohammad Iqbal Adom, Abdul Hamid Shakaff, Ali Yeon Kamarudin, Latifah Munirah Yusuf, Nurlisa Hashim, Yumi Zuhanis Has-Yun Mohamed Helmy, Khaled Q Science (General) RC Internal medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) TA213 Engineering machinery, tools, and implements Lack of effective tools to diagnose lung cancer at an early stage has caused high mortality in cancer patients especially in lung cancer patients. Electronic nose (E-Nose) technology is believed to offer non-invasive, rapid and reliable analytic approach by measuring the odour released from cancer to assist medical diagnosis. In this work, using a commercial E-nose (Cyranose-320), we aimed to detect the volatile organic compounds (VOCs) emitted by different types of cancerous cells. The lung cancer cell (A549) and breast cancer cell (MCF-7) were used for this study. Both cells were cultured using Dulbecco’s Modified Eagle’s Medium (DMEM) with 10% of Fetal Bovine Serum (FBS) and incubated for three days. The static headspace of cell cultures and blank medium were directly sniffed by Cyranose-320. The preliminary results from this study showed that, the E-nose is able to detect and distinguish the presence of VOCs in cancerous cells with accuracy of 100% using LDA. To this end, the VOCs emitted from cancerous cells can potentially used as biomarker. 2014-12-08 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/47328/4/47328.pdf application/pdf en http://irep.iium.edu.my/47328/7/47328_Cancer%20detection%20using%20an%20electronic%20nose_Scopus.pdf Thriumani, Reena and Zakaria, Ammar and Jeffree, Amanina Iymia and Hishamuddin, N.A. and Omar, Mohammad Iqbal and Adom, Abdul Hamid and Shakaff, Ali Yeon and Kamarudin, Latifah Munirah and Yusuf, Nurlisa and Hashim, Yumi Zuhanis Has-Yun and Mohamed Helmy, Khaled (2014) Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells. In: 2014 IEEE International Conference on Biomedical Engineering and Sciences, 8th-10th December 2014, Miri, Sarawak. http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=7047609
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	Q Science (General) RC Internal medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) TA213 Engineering machinery, tools, and implements
spellingShingle	Q Science (General) RC Internal medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) TA213 Engineering machinery, tools, and implements Thriumani, Reena Zakaria, Ammar Jeffree, Amanina Iymia Hishamuddin, N.A. Omar, Mohammad Iqbal Adom, Abdul Hamid Shakaff, Ali Yeon Kamarudin, Latifah Munirah Yusuf, Nurlisa Hashim, Yumi Zuhanis Has-Yun Mohamed Helmy, Khaled Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells
description	Lack of effective tools to diagnose lung cancer at an early stage has caused high mortality in cancer patients especially in lung cancer patients. Electronic nose (E-Nose) technology is believed to offer non-invasive, rapid and reliable analytic approach by measuring the odour released from cancer to assist medical diagnosis. In this work, using a commercial E-nose (Cyranose-320), we aimed to detect the volatile organic compounds (VOCs) emitted by different types of cancerous cells. The lung cancer cell (A549) and breast cancer cell (MCF-7) were used for this study. Both cells were cultured using Dulbecco’s Modified Eagle’s Medium (DMEM) with 10% of Fetal Bovine Serum (FBS) and incubated for three days. The static headspace of cell cultures and blank medium were directly sniffed by Cyranose-320. The preliminary results from this study showed that, the E-nose is able to detect and distinguish the presence of VOCs in cancerous cells with accuracy of 100% using LDA. To this end, the VOCs emitted from cancerous cells can potentially used as biomarker.
format	Conference or Workshop Item
author	Thriumani, Reena Zakaria, Ammar Jeffree, Amanina Iymia Hishamuddin, N.A. Omar, Mohammad Iqbal Adom, Abdul Hamid Shakaff, Ali Yeon Kamarudin, Latifah Munirah Yusuf, Nurlisa Hashim, Yumi Zuhanis Has-Yun Mohamed Helmy, Khaled
author_facet	Thriumani, Reena Zakaria, Ammar Jeffree, Amanina Iymia Hishamuddin, N.A. Omar, Mohammad Iqbal Adom, Abdul Hamid Shakaff, Ali Yeon Kamarudin, Latifah Munirah Yusuf, Nurlisa Hashim, Yumi Zuhanis Has-Yun Mohamed Helmy, Khaled
author_sort	Thriumani, Reena
title	Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells
title_short	Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells
title_full	Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells
title_fullStr	Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells
title_full_unstemmed	Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells
title_sort	cancer detection using an electronic nose: a preliminary study on detection and discrimination of cancerous cells
publishDate	2014
url	http://irep.iium.edu.my/47328/ http://irep.iium.edu.my/47328/ http://irep.iium.edu.my/47328/4/47328.pdf http://irep.iium.edu.my/47328/7/47328_Cancer%20detection%20using%20an%20electronic%20nose_Scopus.pdf
first_indexed	2023-09-18T21:07:21Z
last_indexed	2023-09-18T21:07:21Z
_version_	1777411022465794048

Cancer detection using an electronic nose: A preliminary study on detection and discrimination of cancerous cells

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