Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics

Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics

tIpomoea aquatica Forsk is a green leafy vegetable that is a rich source of secondary metabolites, vitaminsand amino acids with many health benefits. Proton Nuclear Magnetic Resonance (1H NMR) spectroscopywas combined with multivariate data analyses to distinguish Ipomoea aquatica samples at differe...

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Main Authors: Lawal, Umar, Mediani, Ahmed, H., Maulidiani, Shaari, Khozirah, Ismail, Intan Safinar, Khatib, Alfi, Abas, Faridah
Format: Article
Language:English
Published: Elsevier 2015
Subjects:
QD Chemistry
Online Access:http://irep.iium.edu.my/45217/
http://irep.iium.edu.my/45217/
http://irep.iium.edu.my/45217/
http://irep.iium.edu.my/45217/1/lawal_et_al_2015.pdf
id iium-45217
recordtype eprints
spelling iium-452172016-02-23T07:08:38Z http://irep.iium.edu.my/45217/ Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics Lawal, Umar Mediani, Ahmed H., Maulidiani Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah QD Chemistry tIpomoea aquatica Forsk is a green leafy vegetable that is a rich source of secondary metabolites, vitaminsand amino acids with many health benefits. Proton Nuclear Magnetic Resonance (1H NMR) spectroscopywas combined with multivariate data analyses to distinguish Ipomoea aquatica samples at different devel-opmental stages. A principal component analysis (PCA) of Ipomoea leaves provides clusters based on thedifferent developmental stages by combining principal components PC1 and PC2 with a total varianceof 65.1%. A loading plot analysis revealed that the initial stages (weeks 3 and 4) showed comparativelylow contents of phenolic and organic acids, such as citric and maleic acid; the latter stages (weeks 5and 6) exhibited higher glucose and phenolic compound contents. The sugar, phenolic compound andorganic acid contents increased based on the developmental stage of the Ipomoea aquatica. The latentstructures were projected using a partial least squares (PLS) model to predict the biological activity of theIpomoea extracts based on their1H NMR spectra. The results of this study indicate that1H NMR-basedmetabolomics data could be used to discriminate the different developmental stages and to predict thebiological activities of Ipomoea leaves. The present study may be applied when monitoring the quality offruits and vegetables. Elsevier 2015-08-31 Article PeerReviewed application/pdf en http://irep.iium.edu.my/45217/1/lawal_et_al_2015.pdf Lawal, Umar and Mediani, Ahmed and H., Maulidiani and Shaari, Khozirah and Ismail, Intan Safinar and Khatib, Alfi and Abas, Faridah (2015) Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics. Scientia Horticulturae, 192. pp. 400-408. ISSN 0304-4238 http://www.sciencedirect.com/science/article/pii/S0304423815300601 10.1016/j.scienta.2015.06.036
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic QD Chemistry
spellingShingle QD Chemistry
Lawal, Umar
Mediani, Ahmed
H., Maulidiani
Shaari, Khozirah
Ismail, Intan Safinar
Khatib, Alfi
Abas, Faridah
Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics
description tIpomoea aquatica Forsk is a green leafy vegetable that is a rich source of secondary metabolites, vitaminsand amino acids with many health benefits. Proton Nuclear Magnetic Resonance (1H NMR) spectroscopywas combined with multivariate data analyses to distinguish Ipomoea aquatica samples at different devel-opmental stages. A principal component analysis (PCA) of Ipomoea leaves provides clusters based on thedifferent developmental stages by combining principal components PC1 and PC2 with a total varianceof 65.1%. A loading plot analysis revealed that the initial stages (weeks 3 and 4) showed comparativelylow contents of phenolic and organic acids, such as citric and maleic acid; the latter stages (weeks 5and 6) exhibited higher glucose and phenolic compound contents. The sugar, phenolic compound andorganic acid contents increased based on the developmental stage of the Ipomoea aquatica. The latentstructures were projected using a partial least squares (PLS) model to predict the biological activity of theIpomoea extracts based on their1H NMR spectra. The results of this study indicate that1H NMR-basedmetabolomics data could be used to discriminate the different developmental stages and to predict thebiological activities of Ipomoea leaves. The present study may be applied when monitoring the quality offruits and vegetables.
format Article
author Lawal, Umar
Mediani, Ahmed
H., Maulidiani
Shaari, Khozirah
Ismail, Intan Safinar
Khatib, Alfi
Abas, Faridah
author_facet Lawal, Umar
Mediani, Ahmed
H., Maulidiani
Shaari, Khozirah
Ismail, Intan Safinar
Khatib, Alfi
Abas, Faridah
author_sort Lawal, Umar
title Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics
title_short Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics
title_full Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics
title_fullStr Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics
title_full_unstemmed Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by H-1 NMR-based metabolomics
title_sort metabolite profiling of ipomoea aquatica at different growth stages in correlation to the antioxidant and alpha-glucosidase inhibitory activities elucidated by h-1 nmr-based metabolomics
publisher Elsevier
publishDate 2015
url http://irep.iium.edu.my/45217/
http://irep.iium.edu.my/45217/
http://irep.iium.edu.my/45217/
http://irep.iium.edu.my/45217/1/lawal_et_al_2015.pdf
first_indexed 2023-09-18T21:04:21Z
last_indexed 2023-09-18T21:04:21Z
_version_ 1777410833349869568

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