Evaluation of the antifungal effect of saliva officinalis extract in vitro

Background/Objectives: Saliva officinalis (sage) is a natural product that has been given more consideration these days because of its beneficial health effect. There are a lot of active Compounds from S. officinalis essential oil have been shown to exhibit high antibacterial activity against Staphy...

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Main Authors:	Mustafa Al-Ahmad, Basma Ezzat, Mustafa, Nazih Shaban, Kashmola, Muhanad Ali Hamdon, Quta, Lolita, Shaban , Sama
Format:	Conference or Workshop Item
Language:	English
Published:	2015
Subjects:	Q Science (General) RK Dentistry
Online Access:	http://irep.iium.edu.my/44994/ http://irep.iium.edu.my/44994/ http://irep.iium.edu.my/44994/1/MJM_Dr_Basma_2015_Antifungal_effect.pdf

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recordtype	eprints
spelling	iium-449942016-05-20T08:09:32Z http://irep.iium.edu.my/44994/ Evaluation of the antifungal effect of saliva officinalis extract in vitro Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Quta, Lolita Shaban , Sama Q Science (General) RK Dentistry Background/Objectives: Saliva officinalis (sage) is a natural product that has been given more consideration these days because of its beneficial health effect. There are a lot of active Compounds from S. officinalis essential oil have been shown to exhibit high antibacterial activity against Staphyloccocus aureus, Escherichia coli, and Pseudomonas aeruginosa; however, there are only few studies on its antifungal effects. The aim of this research is to investigate antifungal ability of different types of Saliva officinalis extract in vitro, and to compare their potency. Materials and Method: Oil and water-based extracts of Saliva officinalis were used in this study in different concentrations, compared to Nystatin(100 units) as a positive control. Inhibitory effect of different concentrations of Saliva officinalis extract on candida albicans was studied under in vitro conditions. The antifungal activity of the extract was measured by percent radial growth inhibition. 500 ppm of the extract was found to have a high inhibitory effect on candida albicance growth. Results & Discussion: Assessment of conidial growth by using different concentrations showed that the oil extract exhibited 90 % inhibition of candidal growth at 500 ppm, comparing to the water extract which exhibited only 40% inhibition of the growth in the same concentration ,according to this study the fungicidal concentrations of S. officinalis oil is 500 ppm . It was found that Sage oil was more than the water extract. Conclusion: this study shows that oil extract has high antifungal activity comparing to the water extract .Based upon the present study it could be concluded that Saliva officinalis oil extract might be promising as a mouth wash in reducing the fungal growth in oral cavity and the incidence of side effect that may occur with some synthetic product. 2015 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/44994/1/MJM_Dr_Basma_2015_Antifungal_effect.pdf Mustafa Al-Ahmad, Basma Ezzat and Mustafa, Nazih Shaban and Kashmola, Muhanad Ali Hamdon and Quta, Lolita and Shaban , Sama (2015) Evaluation of the antifungal effect of saliva officinalis extract in vitro. In: International Anatomical and Biomedical Scientific Conference 2015 IABS 2015, 18–20 Aug 2015, Universiti Putra Malaysia. http://iabs2015.maa.net.my/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General) RK Dentistry
spellingShingle	Q Science (General) RK Dentistry Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Quta, Lolita Shaban , Sama Evaluation of the antifungal effect of saliva officinalis extract in vitro
description	Background/Objectives: Saliva officinalis (sage) is a natural product that has been given more consideration these days because of its beneficial health effect. There are a lot of active Compounds from S. officinalis essential oil have been shown to exhibit high antibacterial activity against Staphyloccocus aureus, Escherichia coli, and Pseudomonas aeruginosa; however, there are only few studies on its antifungal effects. The aim of this research is to investigate antifungal ability of different types of Saliva officinalis extract in vitro, and to compare their potency. Materials and Method: Oil and water-based extracts of Saliva officinalis were used in this study in different concentrations, compared to Nystatin(100 units) as a positive control. Inhibitory effect of different concentrations of Saliva officinalis extract on candida albicans was studied under in vitro conditions. The antifungal activity of the extract was measured by percent radial growth inhibition. 500 ppm of the extract was found to have a high inhibitory effect on candida albicance growth. Results & Discussion: Assessment of conidial growth by using different concentrations showed that the oil extract exhibited 90 % inhibition of candidal growth at 500 ppm, comparing to the water extract which exhibited only 40% inhibition of the growth in the same concentration ,according to this study the fungicidal concentrations of S. officinalis oil is 500 ppm . It was found that Sage oil was more than the water extract. Conclusion: this study shows that oil extract has high antifungal activity comparing to the water extract .Based upon the present study it could be concluded that Saliva officinalis oil extract might be promising as a mouth wash in reducing the fungal growth in oral cavity and the incidence of side effect that may occur with some synthetic product.
format	Conference or Workshop Item
author	Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Quta, Lolita Shaban , Sama
author_facet	Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Quta, Lolita Shaban , Sama
author_sort	Mustafa Al-Ahmad, Basma Ezzat
title	Evaluation of the antifungal effect of saliva officinalis extract in vitro
title_short	Evaluation of the antifungal effect of saliva officinalis extract in vitro
title_full	Evaluation of the antifungal effect of saliva officinalis extract in vitro
title_fullStr	Evaluation of the antifungal effect of saliva officinalis extract in vitro
title_full_unstemmed	Evaluation of the antifungal effect of saliva officinalis extract in vitro
title_sort	evaluation of the antifungal effect of saliva officinalis extract in vitro
publishDate	2015
url	http://irep.iium.edu.my/44994/ http://irep.iium.edu.my/44994/ http://irep.iium.edu.my/44994/1/MJM_Dr_Basma_2015_Antifungal_effect.pdf
first_indexed	2023-09-18T21:03:59Z
last_indexed	2023-09-18T21:03:59Z
_version_	1777410810374520832

Evaluation of the antifungal effect of saliva officinalis extract in vitro

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