α-glucosidase and 15-lipoxygenase inhibitory activities of phytochemicals from calophyllum symingtonianum
A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone, isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical structures were elucidated and confirme...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
Natural Product Inc.
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/44955/ http://irep.iium.edu.my/44955/ http://irep.iium.edu.my/44955/1/2015-Calophyllum.pdf http://irep.iium.edu.my/44955/4/44955_%CE%B1-Glucosidase%20and%2015-lipoxygenase%20inhibitory%20activities_Scopus.pdf http://irep.iium.edu.my/44955/5/44955_%CE%B1-Glucosidase%20and%2015-lipoxygenase%20inhibitory%20activities_WOS.pdf |
| Summary: | A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum symingtonianum has resulted in the isolation of inophyllum D,
inophyllum H, calanone, isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical structures were elucidated and confirmed by spectroscopic analysis. All flavonoids and coumarins showed significant α-glucosidase inhibitory activity, while amentoflavone gave a positive result against 15-lipoxygenase inhibition. |
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