Simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment

A novel sonication decellularization system is developed to prepare complete decellularized tissue. The objective of the study is to determine the influence of acoustic intensity on sonication parameter and decellularization using sonication treatment. The distribution of acoustic intensity for soni...

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Main Authors: ., Nurul Syazwani, Shafiq, Mohammad, Ushida, Takashi, Noor Azmi, Azran Azhim
Format: Article
Language:English
Published: J-Stage 2015
Subjects:
Online Access:http://irep.iium.edu.my/44506/
http://irep.iium.edu.my/44506/
http://irep.iium.edu.my/44506/1/journal_of_signal_processing_-_decellularization.pdf
id iium-44506
recordtype eprints
spelling iium-445062017-06-16T01:22:26Z http://irep.iium.edu.my/44506/ Simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment ., Nurul Syazwani Shafiq, Mohammad Ushida, Takashi Noor Azmi, Azran Azhim TP248.13 Biotechnology A novel sonication decellularization system is developed to prepare complete decellularized tissue. The objective of the study is to determine the influence of acoustic intensity on sonication parameter and decellularization using sonication treatment. The distribution of acoustic intensity for sonication treatment is first demonstrated by simulation followed by experimental measurement. The relation of acoustic intensity with sonication parameter on decellularization is further investigated. The effect of acoustic intensity on decellularization is evaluated by measuring the residual cell in tissue sample using Hematoxylin-Eosin staining. The simulation shows low residual cells upon high acoustic intensity. From the result, acoustic intensity shows positive correlation with dissolved oxygen concentration and pH and negative correlation with conductivity. The present study concludes that decellularization performed by sonication treatment is dependent on acoustic intensity. J-Stage 2015-07 Article PeerReviewed application/pdf en http://irep.iium.edu.my/44506/1/journal_of_signal_processing_-_decellularization.pdf ., Nurul Syazwani and Shafiq, Mohammad and Ushida, Takashi and Noor Azmi, Azran Azhim (2015) Simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment. Journal of Signal Processing, 19 (4). pp. 179-182. ISSN 1880-1013 https://www.j3.jstage.jst.go.jp/article/jsp/19/4/19_179/_article/-char/ja/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic TP248.13 Biotechnology
spellingShingle TP248.13 Biotechnology
., Nurul Syazwani
Shafiq, Mohammad
Ushida, Takashi
Noor Azmi, Azran Azhim
Simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment
description A novel sonication decellularization system is developed to prepare complete decellularized tissue. The objective of the study is to determine the influence of acoustic intensity on sonication parameter and decellularization using sonication treatment. The distribution of acoustic intensity for sonication treatment is first demonstrated by simulation followed by experimental measurement. The relation of acoustic intensity with sonication parameter on decellularization is further investigated. The effect of acoustic intensity on decellularization is evaluated by measuring the residual cell in tissue sample using Hematoxylin-Eosin staining. The simulation shows low residual cells upon high acoustic intensity. From the result, acoustic intensity shows positive correlation with dissolved oxygen concentration and pH and negative correlation with conductivity. The present study concludes that decellularization performed by sonication treatment is dependent on acoustic intensity.
format Article
author ., Nurul Syazwani
Shafiq, Mohammad
Ushida, Takashi
Noor Azmi, Azran Azhim
author_facet ., Nurul Syazwani
Shafiq, Mohammad
Ushida, Takashi
Noor Azmi, Azran Azhim
author_sort ., Nurul Syazwani
title Simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment
title_short Simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment
title_full Simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment
title_fullStr Simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment
title_full_unstemmed Simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment
title_sort simulation and experimental measurement of acoustic intensity on sonication parameters and decellularization using sonication treatment
publisher J-Stage
publishDate 2015
url http://irep.iium.edu.my/44506/
http://irep.iium.edu.my/44506/
http://irep.iium.edu.my/44506/1/journal_of_signal_processing_-_decellularization.pdf
first_indexed 2023-09-18T21:03:17Z
last_indexed 2023-09-18T21:03:17Z
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