Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity

The evolution of resistant microorganism towards available antibiotics has gain interest among scientists to search for more effective antimicrobial compounds. Plant is believe to have antimicrobial properties as the extract is used in food industry, pharmaceuticals and alternative medicine. The aim...

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Main Authors:	Sulaiman, Fatimatul Akma, Darnis, Deny Susanti, Mohamed Iqbal, Mohammad Anwar, Miskam, Mazidatulakmam Akmam
Format:	Conference or Workshop Item
Language:	English
Published:	2015
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/44394/ http://irep.iium.edu.my/44394/ http://irep.iium.edu.my/44394/6/fatimatulakmal.pdf

id	iium-44394
recordtype	eprints
spelling	iium-443942018-05-22T03:44:25Z http://irep.iium.edu.my/44394/ Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity Sulaiman, Fatimatul Akma Darnis, Deny Susanti Mohamed Iqbal, Mohammad Anwar Miskam, Mazidatulakmam Akmam QD Chemistry The evolution of resistant microorganism towards available antibiotics has gain interest among scientists to search for more effective antimicrobial compounds. Plant is believe to have antimicrobial properties as the extract is used in food industry, pharmaceuticals and alternative medicine. The aims of this study are to isolate secondary metabolites from Q. infectoria galls and to elucidate structure of the isolated compound using spectroscopic techniques and determination of antimicrobial activity. The galls were extracted with organic solvent using soxhlet apparatus and fractionated using chromatographic techniques. The isolated compounds were characterized using spectroscopic techniques such as UV spectrophotometer, Fourier Transform Infrared Spectroscopy (FTIR), Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS). The antimicrobial activities are determined using disc diffusion method, determination of MIC, MBC, MFC and synergistic effect. The disc diffusion test against Staphylococcus aureus showed zone of inhibition 7 mm (n-hexane extract) and 9 mm (methanol extract). Meanwhile, dichloromethane extract showed no inhibition against S. aureus. It is expected that the isolated compound have antimicrobial properties and synergistic effect in combination with standard antibiotic. 2015 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/44394/6/fatimatulakmal.pdf Sulaiman, Fatimatul Akma and Darnis, Deny Susanti and Mohamed Iqbal, Mohammad Anwar and Miskam, Mazidatulakmam Akmam (2015) Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity. In: 5th International Conference on Advancement in Science and Technology (iCAST 2015), 10-12 August 2015, Impiana Resort Cherating. (Unpublished) http://www.iium.edu.my/icast
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Sulaiman, Fatimatul Akma Darnis, Deny Susanti Mohamed Iqbal, Mohammad Anwar Miskam, Mazidatulakmam Akmam Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity
description	The evolution of resistant microorganism towards available antibiotics has gain interest among scientists to search for more effective antimicrobial compounds. Plant is believe to have antimicrobial properties as the extract is used in food industry, pharmaceuticals and alternative medicine. The aims of this study are to isolate secondary metabolites from Q. infectoria galls and to elucidate structure of the isolated compound using spectroscopic techniques and determination of antimicrobial activity. The galls were extracted with organic solvent using soxhlet apparatus and fractionated using chromatographic techniques. The isolated compounds were characterized using spectroscopic techniques such as UV spectrophotometer, Fourier Transform Infrared Spectroscopy (FTIR), Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS). The antimicrobial activities are determined using disc diffusion method, determination of MIC, MBC, MFC and synergistic effect. The disc diffusion test against Staphylococcus aureus showed zone of inhibition 7 mm (n-hexane extract) and 9 mm (methanol extract). Meanwhile, dichloromethane extract showed no inhibition against S. aureus. It is expected that the isolated compound have antimicrobial properties and synergistic effect in combination with standard antibiotic.
format	Conference or Workshop Item
author	Sulaiman, Fatimatul Akma Darnis, Deny Susanti Mohamed Iqbal, Mohammad Anwar Miskam, Mazidatulakmam Akmam
author_facet	Sulaiman, Fatimatul Akma Darnis, Deny Susanti Mohamed Iqbal, Mohammad Anwar Miskam, Mazidatulakmam Akmam
author_sort	Sulaiman, Fatimatul Akma
title	Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity
title_short	Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity
title_full	Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity
title_fullStr	Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity
title_full_unstemmed	Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity
title_sort	isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity
publishDate	2015
url	http://irep.iium.edu.my/44394/ http://irep.iium.edu.my/44394/ http://irep.iium.edu.my/44394/6/fatimatulakmal.pdf
first_indexed	2023-09-18T21:03:07Z
last_indexed	2023-09-18T21:03:07Z
_version_	1777410755427041280

Isolation of secondary metabolites from quercus infectoria galls and their antimicrobial activity

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