A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies

A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies

In this paper, we report on an expandable height hydrogel stamper with built-in reservoir that can be used to repeatedly (without frequent re-inking) stamp functional biomolecules on planar and non-planar surfaces. We have successfully patterned fluorescein isothiocyante (FITC) labeled antibodie...

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Main Authors: Wan Salim, Wan Wardatul Amani, Ding, Zhenweng, Ziaie, Babak
Format: Conference or Workshop Item
Language:English
Published: IEEE 2008
Subjects:
TA164 Bioengineering
Online Access:http://irep.iium.edu.my/44332/
http://irep.iium.edu.my/44332/
http://irep.iium.edu.my/44332/
http://irep.iium.edu.my/44332/7/44332%20A%20Hydrogel%20Stamper%20with%20Expandable%20Height.pdf
id iium-44332
recordtype eprints
spelling iium-443322020-02-11T03:06:01Z http://irep.iium.edu.my/44332/ A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies Wan Salim, Wan Wardatul Amani Ding, Zhenweng Ziaie, Babak TA164 Bioengineering In this paper, we report on an expandable height hydrogel stamper with built-in reservoir that can be used to repeatedly (without frequent re-inking) stamp functional biomolecules on planar and non-planar surfaces. We have successfully patterned fluorescein isothiocyante (FITC) labeled antibodies (antibodies for O-antigens of Bradyrhizobium japonicum made in rabbits) on planar (silicon) and nonplanar (SU8 on silicon with a height of ~ 70µm) topologies. The printed antibodies show the effectiveness of hydrogel stampers in delivering biomolecules on 3D topologies where the hydrogel could be adjusted to stamp on the sidewalls and bottom of deep trenches. IEEE 2008-01-21 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/44332/7/44332%20A%20Hydrogel%20Stamper%20with%20Expandable%20Height.pdf Wan Salim, Wan Wardatul Amani and Ding, Zhenweng and Ziaie, Babak (2008) A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies. In: 2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS), 21st-25 January 2007, Kobe, Japan. https://ieeexplore.ieee.org/document/4433117 10.1109/MEMSYS.2007.4433117
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic TA164 Bioengineering
spellingShingle TA164 Bioengineering
Wan Salim, Wan Wardatul Amani
Ding, Zhenweng
Ziaie, Babak
A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies
description In this paper, we report on an expandable height hydrogel stamper with built-in reservoir that can be used to repeatedly (without frequent re-inking) stamp functional biomolecules on planar and non-planar surfaces. We have successfully patterned fluorescein isothiocyante (FITC) labeled antibodies (antibodies for O-antigens of Bradyrhizobium japonicum made in rabbits) on planar (silicon) and nonplanar (SU8 on silicon with a height of ~ 70µm) topologies. The printed antibodies show the effectiveness of hydrogel stampers in delivering biomolecules on 3D topologies where the hydrogel could be adjusted to stamp on the sidewalls and bottom of deep trenches.
format Conference or Workshop Item
author Wan Salim, Wan Wardatul Amani
Ding, Zhenweng
Ziaie, Babak
author_facet Wan Salim, Wan Wardatul Amani
Ding, Zhenweng
Ziaie, Babak
author_sort Wan Salim, Wan Wardatul Amani
title A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies
title_short A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies
title_full A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies
title_fullStr A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies
title_full_unstemmed A hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3D topologies
title_sort hydrogel stamper with expandable height and built-in reservoirs for patterning biomolecules on 3d topologies
publisher IEEE
publishDate 2008
url http://irep.iium.edu.my/44332/
http://irep.iium.edu.my/44332/
http://irep.iium.edu.my/44332/
http://irep.iium.edu.my/44332/7/44332%20A%20Hydrogel%20Stamper%20with%20Expandable%20Height.pdf
first_indexed 2023-09-18T21:03:03Z
last_indexed 2023-09-18T21:03:03Z
_version_ 1777410751728713728

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