A hydrogel-actuated microvalve for smart flow control
In this paper, we report on the fabrication and testing of a hydrogel-actuated smart microvalve for biomedical applications. The three-layered microvalve is composed of a stimuli-sensitive ìintelligentî hydrogel sandwiched between a porous silicon membrane and a bossed PDMS flexible diaphragm. The...
| Main Authors: | , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
IEEE
2004
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/44329/ http://irep.iium.edu.my/44329/ http://irep.iium.edu.my/44329/ http://irep.iium.edu.my/44329/7/44329%20A%20Hydrogel-Actuated%20Microvalve.pdf |
| Summary: | In this paper, we report on the fabrication and
testing of a hydrogel-actuated smart microvalve for biomedical applications. The three-layered microvalve is composed of a stimuli-sensitive ìintelligentî hydrogel sandwiched between a porous silicon membrane and a bossed PDMS flexible diaphragm. The entrapped hydrogel in response to changes in the external physiological stimuli (e.g., pH, glucose, etc.), which diffuses through the porous membrane, swelles and deswelles hence deflecting the flexible PDMS diaphragm and controlling the closure and opening of the microvalve inlet. A microvalve
incorporating a 155µm thick hydrogel (poly(methacrylic
acid-co-acrylamide), mAA-co-AAm) has a response time of
3.6 min to a sudden pH change (pH=3 to pH=7). |
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