Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction

Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction

Background Myocardial scar and edema can be assessed by late gadolinium enhancement (LGE) and T2W cardiac magnetic resonance (CMR) respectively, but each has important limitations. T1-mapping has emerged as an alternative method to characterize acute ischemic injury and contemporary mapping sequenc...

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Main Authors: Mohd Shah, Azarisman Shah, Li, Andrew, Wong, Dennis T., Richardson, James D., Chua, Seng Keong, Samaraie, Luay, Sidharta, Samuel L, Glenie, Timothy, Williams, Kerry, Koschade, Ben, Teo, Karen, Worthley, Matthew, Worthley, Stephen G.
Format: Article
Language:English
Published: Society for Cardiovascular Magnetic Resonance (SCMR) 2013
Subjects:
RC Internal medicine
Online Access:http://irep.iium.edu.my/44312/
http://irep.iium.edu.my/44312/
http://irep.iium.edu.my/44312/1/1532-429X-15-S1-E33.pdf
id iium-44312
recordtype eprints
spelling iium-443122015-08-21T01:26:20Z http://irep.iium.edu.my/44312/ Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction Mohd Shah, Azarisman Shah Li, Andrew Wong, Dennis T. Richardson, James D. Chua, Seng Keong Samaraie, Luay Sidharta, Samuel L Glenie, Timothy Williams, Kerry Koschade, Ben Teo, Karen Worthley, Matthew Worthley, Stephen G. RC Internal medicine Background Myocardial scar and edema can be assessed by late gadolinium enhancement (LGE) and T2W cardiac magnetic resonance (CMR) respectively, but each has important limitations. T1-mapping has emerged as an alternative method to characterize acute ischemic injury and contemporary mapping sequences make this clinically feasible. We assessed the T1 relaxation time in myocardial segments exhibiting varying degrees of ischemic injury in patients after acute MI. Methods T2W, T1-mapping (using Shortened Modified Look-Looker Inversion recovery sequence) and LGE imaging was performed 24-72 hours after MI on a 1.5T scanner. Assessment of acute segmental damage, in a 16-segment AHA model, was performed on matched short axis slices. Mean segmental T1 values were calculated for infarcted, adjacent/edema, microvascular obstruction (MVO) or remote segments as defined by LGE. Society for Cardiovascular Magnetic Resonance (SCMR) 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/44312/1/1532-429X-15-S1-E33.pdf Mohd Shah, Azarisman Shah and Li, Andrew and Wong, Dennis T. and Richardson, James D. and Chua, Seng Keong and Samaraie, Luay and Sidharta, Samuel L and Glenie, Timothy and Williams, Kerry and Koschade, Ben and Teo, Karen and Worthley, Matthew and Worthley, Stephen G. (2013) Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction. Journal of Cardiovascular Magnetic Resonance, 15 (supp.1). E33. ISSN 1532-429X http://www.jcmr-online.com/content/15/S1/E33
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RC Internal medicine
spellingShingle RC Internal medicine
Mohd Shah, Azarisman Shah
Li, Andrew
Wong, Dennis T.
Richardson, James D.
Chua, Seng Keong
Samaraie, Luay
Sidharta, Samuel L
Glenie, Timothy
Williams, Kerry
Koschade, Ben
Teo, Karen
Worthley, Matthew
Worthley, Stephen G.
Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction
description Background Myocardial scar and edema can be assessed by late gadolinium enhancement (LGE) and T2W cardiac magnetic resonance (CMR) respectively, but each has important limitations. T1-mapping has emerged as an alternative method to characterize acute ischemic injury and contemporary mapping sequences make this clinically feasible. We assessed the T1 relaxation time in myocardial segments exhibiting varying degrees of ischemic injury in patients after acute MI. Methods T2W, T1-mapping (using Shortened Modified Look-Looker Inversion recovery sequence) and LGE imaging was performed 24-72 hours after MI on a 1.5T scanner. Assessment of acute segmental damage, in a 16-segment AHA model, was performed on matched short axis slices. Mean segmental T1 values were calculated for infarcted, adjacent/edema, microvascular obstruction (MVO) or remote segments as defined by LGE.
format Article
author Mohd Shah, Azarisman Shah
Li, Andrew
Wong, Dennis T.
Richardson, James D.
Chua, Seng Keong
Samaraie, Luay
Sidharta, Samuel L
Glenie, Timothy
Williams, Kerry
Koschade, Ben
Teo, Karen
Worthley, Matthew
Worthley, Stephen G.
author_facet Mohd Shah, Azarisman Shah
Li, Andrew
Wong, Dennis T.
Richardson, James D.
Chua, Seng Keong
Samaraie, Luay
Sidharta, Samuel L
Glenie, Timothy
Williams, Kerry
Koschade, Ben
Teo, Karen
Worthley, Matthew
Worthley, Stephen G.
author_sort Mohd Shah, Azarisman Shah
title Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction
title_short Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction
title_full Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction
title_fullStr Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction
title_full_unstemmed Tissue injury characterization by pre-contrast T1 mapping post myocardial infraction
title_sort tissue injury characterization by pre-contrast t1 mapping post myocardial infraction
publisher Society for Cardiovascular Magnetic Resonance (SCMR)
publishDate 2013
url http://irep.iium.edu.my/44312/
http://irep.iium.edu.my/44312/
http://irep.iium.edu.my/44312/1/1532-429X-15-S1-E33.pdf
first_indexed 2023-09-18T21:03:01Z
last_indexed 2023-09-18T21:03:01Z
_version_ 1777410749348446208

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