Exercise improved age-associated changes in the carotid blood velocity waveforms

Exercise improved age-associated changes in the carotid blood velocity waveforms

Physiological blood flow velocity in common carotid artery (CCA) is altered markedly with advancing age. It is unknown that regular aerobic exercise is able to improve blood flow velocity waveforms in either healthy young or healthy older individuals. We investigate the role of regular exercise on...

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Main Authors: Noor Azmi, Azran Azhim, M. , Katai, M., Akutagawa, Y., Hirao, K., Yoshizaki, S., Obara, M. , Nomura, H., Tanaka, H., Yamaguchi, Y., Kinouchi
Format: Article
Language:English
Published: Biomedical & Pharmaceutical Engineering Cluster, Nanyang Technological University 2007
Subjects:
TP248.13 Biotechnology
Online Access:http://irep.iium.edu.my/44122/
http://irep.iium.edu.my/44122/
http://irep.iium.edu.my/44122/1/Exercise_Improved_Age-associated_Changes_in_the_Carotid_Blood.pdf
id iium-44122
recordtype eprints
spelling iium-441222015-08-17T03:28:16Z http://irep.iium.edu.my/44122/ Exercise improved age-associated changes in the carotid blood velocity waveforms Noor Azmi, Azran Azhim M. , Katai M., Akutagawa Y., Hirao K., Yoshizaki S., Obara M. , Nomura H., Tanaka H., Yamaguchi Y., Kinouchi TP248.13 Biotechnology Physiological blood flow velocity in common carotid artery (CCA) is altered markedly with advancing age. It is unknown that regular aerobic exercise is able to improve blood flow velocity waveforms in either healthy young or healthy older individuals. We investigate the role of regular exercise on the age-associated alterations in blood velocity waveforms in CCA by using cross-sectional and intervention approaches. First, we study 91 putatively healthy volunteers with age range of 20-76 years: 65 subjects are sedentary and 26 subjects are regular exercisetrained. We assess the blood velocities at rest in peak systolic (S1), second systolic (S2), incisura between systole (I) and peak diastolic (D), and end-diastolic (d) in young, middle-aged and older subjects. Blood velocities in S1 are higher in exercise-trained, whereas S2, D and d are not different between trained and sedentary individuals. However, the indices of S1/S2 and D/I have marked higher values in exercise-trained adults. Second, we study 7 young sedentary healthy subjects before and after 1-month aerobic exercise intervention. The aerobic exercise increases whole velocity waveforms in CCA with association of decreased heart rate. In conclusion, regular exercise improves age-associated decrease in blood flow velocities in the healthy young, middle-aged and older individuals and restores levels after 1-month exercise in previously sedentary young men. Biomedical & Pharmaceutical Engineering Cluster, Nanyang Technological University 2007 Article PeerReviewed application/pdf en http://irep.iium.edu.my/44122/1/Exercise_Improved_Age-associated_Changes_in_the_Carotid_Blood.pdf Noor Azmi, Azran Azhim and M. , Katai and M., Akutagawa and Y., Hirao and K., Yoshizaki and S., Obara and M. , Nomura and H., Tanaka and H., Yamaguchi and Y., Kinouchi (2007) Exercise improved age-associated changes in the carotid blood velocity waveforms. Journal of Biomedical & Pharmaceutical Engineering , 1 (1). pp. 17-26. ISSN 1793-4532 http://www3.ntu.edu.sg/bmerc/contents/JBPE/J001/JBPE%201(1);%2017-26.pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic TP248.13 Biotechnology
spellingShingle TP248.13 Biotechnology
Noor Azmi, Azran Azhim
M. , Katai
M., Akutagawa
Y., Hirao
K., Yoshizaki
S., Obara
M. , Nomura
H., Tanaka
H., Yamaguchi
Y., Kinouchi
Exercise improved age-associated changes in the carotid blood velocity waveforms
description Physiological blood flow velocity in common carotid artery (CCA) is altered markedly with advancing age. It is unknown that regular aerobic exercise is able to improve blood flow velocity waveforms in either healthy young or healthy older individuals. We investigate the role of regular exercise on the age-associated alterations in blood velocity waveforms in CCA by using cross-sectional and intervention approaches. First, we study 91 putatively healthy volunteers with age range of 20-76 years: 65 subjects are sedentary and 26 subjects are regular exercisetrained. We assess the blood velocities at rest in peak systolic (S1), second systolic (S2), incisura between systole (I) and peak diastolic (D), and end-diastolic (d) in young, middle-aged and older subjects. Blood velocities in S1 are higher in exercise-trained, whereas S2, D and d are not different between trained and sedentary individuals. However, the indices of S1/S2 and D/I have marked higher values in exercise-trained adults. Second, we study 7 young sedentary healthy subjects before and after 1-month aerobic exercise intervention. The aerobic exercise increases whole velocity waveforms in CCA with association of decreased heart rate. In conclusion, regular exercise improves age-associated decrease in blood flow velocities in the healthy young, middle-aged and older individuals and restores levels after 1-month exercise in previously sedentary young men.
format Article
author Noor Azmi, Azran Azhim
M. , Katai
M., Akutagawa
Y., Hirao
K., Yoshizaki
S., Obara
M. , Nomura
H., Tanaka
H., Yamaguchi
Y., Kinouchi
author_facet Noor Azmi, Azran Azhim
M. , Katai
M., Akutagawa
Y., Hirao
K., Yoshizaki
S., Obara
M. , Nomura
H., Tanaka
H., Yamaguchi
Y., Kinouchi
author_sort Noor Azmi, Azran Azhim
title Exercise improved age-associated changes in the carotid blood velocity waveforms
title_short Exercise improved age-associated changes in the carotid blood velocity waveforms
title_full Exercise improved age-associated changes in the carotid blood velocity waveforms
title_fullStr Exercise improved age-associated changes in the carotid blood velocity waveforms
title_full_unstemmed Exercise improved age-associated changes in the carotid blood velocity waveforms
title_sort exercise improved age-associated changes in the carotid blood velocity waveforms
publisher Biomedical & Pharmaceutical Engineering Cluster, Nanyang Technological University
publishDate 2007
url http://irep.iium.edu.my/44122/
http://irep.iium.edu.my/44122/
http://irep.iium.edu.my/44122/1/Exercise_Improved_Age-associated_Changes_in_the_Carotid_Blood.pdf
first_indexed 2023-09-18T21:02:46Z
last_indexed 2023-09-18T21:02:46Z
_version_ 1777410733430013952

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