Epigenetic silencing status of p16INK4a and MGMT promoter regions identified qualitatively in diffuse large B cell lymphoma
Apart from genetic mutation, DNA methylation, an epigenetic event, has emerged as an important genomic disorder which silences the gene through addition of methyl group to the cytosines especially in CpG islands located in promoter region. p16, a tumor suppressor gene that inhibits cyclin-dependent...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/43456/ http://irep.iium.edu.my/43456/ http://irep.iium.edu.my/43456/ http://irep.iium.edu.my/43456/1/43456.pdf |