Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars

Antioxidant play an important role in inhibiting and scavenging free radicals, thus providing protection to human against infections and degenerative diseases. Ipomoea aquatica Forsk is a green leafy vegetable that is a rich source of vitamins and amino acids with many health benefits. The present s...

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Main Authors:	Lawal, Umar, Shaari, Khozirah, Ismail, Intan Safinar, Khatib, Alfi, Abas, Faridah
Format:	Conference or Workshop Item
Language:	English
Published:	2015
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/42610/ http://irep.iium.edu.my/42610/ http://irep.iium.edu.my/42610/1/42610.pdf

id	iium-42610
recordtype	eprints
spelling	iium-426102016-05-20T02:56:02Z http://irep.iium.edu.my/42610/ Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars Lawal, Umar Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah Q Science (General) Antioxidant play an important role in inhibiting and scavenging free radicals, thus providing protection to human against infections and degenerative diseases. Ipomoea aquatica Forsk is a green leafy vegetable that is a rich source of vitamins and amino acids with many health benefits. The present study was designed to investigate the effect of using water and methanol at different ratio on the total phenolics, antioxidant capacity and alpha-glucosidase inhibitory of three types of I. aquatica cultivar. The results revealed that 70% methanol extract of K-11 showed higher alpha-glucosidase inhibory and antioxidant activity compare to the other two cultivars. Identification of phytochemical constituents in the active extract (K-11) was carried out by LC-DAAD-ESIMS/MS) reveal the presence of quesrcetin-3-O-sophoroside, quercetin-3-glucosides, 4,5-di-O-caffeoylquinic acid, 3,5-di-O-caffeoylquinic acid, luteolin-7-glucoside and 3,4,5-tricaffeolquinic acid. The identity of the compounds was confirmed by isolation and spectroscopic evidences together with comparison with literature data. This study indicates that 70% methanol is the most efficient solvent for the extraction of polyphenolic compounds from I. aquatica. 2015-03-24 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/42610/1/42610.pdf Lawal, Umar and Shaari, Khozirah and Ismail, Intan Safinar and Khatib, Alfi and Abas, Faridah (2015) Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars. In: International Conference on Natural Products 2015 (ICNP 2015), 24-25 March 2015, Double Tree by Hilton, Johor Bahru. http://science.utm.my/icnp2015/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General)
spellingShingle	Q Science (General) Lawal, Umar Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars
description	Antioxidant play an important role in inhibiting and scavenging free radicals, thus providing protection to human against infections and degenerative diseases. Ipomoea aquatica Forsk is a green leafy vegetable that is a rich source of vitamins and amino acids with many health benefits. The present study was designed to investigate the effect of using water and methanol at different ratio on the total phenolics, antioxidant capacity and alpha-glucosidase inhibitory of three types of I. aquatica cultivar. The results revealed that 70% methanol extract of K-11 showed higher alpha-glucosidase inhibory and antioxidant activity compare to the other two cultivars. Identification of phytochemical constituents in the active extract (K-11) was carried out by LC-DAAD-ESIMS/MS) reveal the presence of quesrcetin-3-O-sophoroside, quercetin-3-glucosides, 4,5-di-O-caffeoylquinic acid, 3,5-di-O-caffeoylquinic acid, luteolin-7-glucoside and 3,4,5-tricaffeolquinic acid. The identity of the compounds was confirmed by isolation and spectroscopic evidences together with comparison with literature data. This study indicates that 70% methanol is the most efficient solvent for the extraction of polyphenolic compounds from I. aquatica.
format	Conference or Workshop Item
author	Lawal, Umar Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah
author_facet	Lawal, Umar Shaari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah
author_sort	Lawal, Umar
title	Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars
title_short	Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars
title_full	Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars
title_fullStr	Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars
title_full_unstemmed	Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars
title_sort	effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of ipomoea aquatica cultivars
publishDate	2015
url	http://irep.iium.edu.my/42610/ http://irep.iium.edu.my/42610/ http://irep.iium.edu.my/42610/1/42610.pdf
first_indexed	2023-09-18T21:00:43Z
last_indexed	2023-09-18T21:00:43Z
_version_	1777410604318851072

Effect of different solvents extraction on antioxidant and alpha glucosidase inhibitory activity of Ipomoea aquatica cultivars

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