The effect of novel flax oil-based implant coating on bone healing process (in vivo animal study)

Objective This pilot study was designed to investigate the effect of new implant coating material on ‎postoperative bone healing process.‎ Study Design experimental formula of flax oil-based implant coating was prepared.Twelve (12) white New Zealand male rabbits were randomly distributed into f...

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Bibliographic Details
Main Authors: Mustafa, Nazih Shaban, Mustafa Al-Ahmad, Basma Ezzat, Kashmola, Muhanad Ali Hamdon
Format: Article
Language:English
English
Published: ELSEVIER 2015
Subjects:
Online Access:http://irep.iium.edu.my/42215/
http://irep.iium.edu.my/42215/
http://irep.iium.edu.my/42215/
http://irep.iium.edu.my/42215/1/flax_seed.docx
http://irep.iium.edu.my/42215/5/Basma.pdf
Description
Summary:Objective This pilot study was designed to investigate the effect of new implant coating material on ‎postoperative bone healing process.‎ Study Design experimental formula of flax oil-based implant coating was prepared.Twelve (12) white New Zealand male rabbits were randomly distributed into four groups (n=3). ‎Surgery was performed to prepare 2mm hole in the zygomatic bone. The right side was ‎filled ‎with the test material (test group). whereas the hole in the left side of the same animal was left ‎material free. Bone healing process was investigated after 3,7,14, and 21 days. ‎ Results New growth of normal bone explained by active bone apposition was observed ‎in the ‎test operation area in the marrow space‎ after three days, less postoperative ‎inflammation was observed explained by less inflammatory cells in the operation area.‎ Conclusıons The new formula could represent a promising implant coating material for better bone healing process and hence faster osseointegration. Keywords Flax seed, coating, implant, Bone, Rabbit