Immunological Changes in Secondary Sjogran Syndrome (Comparative Study)

Objective This study was designed to evaluate the immunological changes and its existence for early diagnosis and proper management of disease. Study Design 56 patients with RA accompanied by sSS where included in this study and compared to 60 RA patients without sSS.Schirmers test, blood tests...

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Main Authors: Mustafa Al-Ahmad, Basma Ezzat, Mustafa, Nazih Shaban, Kashmola, Muhanad Ali Hamdon
Format: Article
Language:English
English
Published: ELSEVIER 2015
Subjects:
Online Access:http://irep.iium.edu.my/42214/
http://irep.iium.edu.my/42214/1/Immunological_Changes_in_Secondary_Sjogran_Syndrome.docx
http://irep.iium.edu.my/42214/5/Basma.pdf
id iium-42214
recordtype eprints
spelling iium-422142015-11-23T23:57:15Z http://irep.iium.edu.my/42214/ Immunological Changes in Secondary Sjogran Syndrome (Comparative Study) Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon R Medicine (General) Objective This study was designed to evaluate the immunological changes and its existence for early diagnosis and proper management of disease. Study Design 56 patients with RA accompanied by sSS where included in this study and compared to 60 RA patients without sSS.Schirmers test, blood tests and search for auto antibodies was done for all patients in both groups. Schirmers, blood tests and search for antinuclear antibody was done for all patients in both groups, with the measurement of salivary flow rate. Results Schirmers test was positive in all sSS and negative in all RA patients, whilst salivary flow rate was reduced in all sSS. Latex fixation test, ANA, Anti Ro and Anti La were reported significantly higher in sSS (p<0.01) Conclusions Secondary Sjogrens syndrome had a significantly positive rheumatoid factor, antinuclear antibody, anti Ro (SS-A) and anti La (SS-B) compared to rheumatoid patients without Sjogrens syndrome. ELSEVIER 2015-03 Article PeerReviewed application/pdf en http://irep.iium.edu.my/42214/1/Immunological_Changes_in_Secondary_Sjogran_Syndrome.docx application/pdf en http://irep.iium.edu.my/42214/5/Basma.pdf Mustafa Al-Ahmad, Basma Ezzat and Mustafa, Nazih Shaban and Kashmola, Muhanad Ali Hamdon (2015) Immunological Changes in Secondary Sjogran Syndrome (Comparative Study). Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 119 (3). e126. ISSN 2212-4411
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic R Medicine (General)
spellingShingle R Medicine (General)
Mustafa Al-Ahmad, Basma Ezzat
Mustafa, Nazih Shaban
Kashmola, Muhanad Ali Hamdon
Immunological Changes in Secondary Sjogran Syndrome (Comparative Study)
description Objective This study was designed to evaluate the immunological changes and its existence for early diagnosis and proper management of disease. Study Design 56 patients with RA accompanied by sSS where included in this study and compared to 60 RA patients without sSS.Schirmers test, blood tests and search for auto antibodies was done for all patients in both groups. Schirmers, blood tests and search for antinuclear antibody was done for all patients in both groups, with the measurement of salivary flow rate. Results Schirmers test was positive in all sSS and negative in all RA patients, whilst salivary flow rate was reduced in all sSS. Latex fixation test, ANA, Anti Ro and Anti La were reported significantly higher in sSS (p<0.01) Conclusions Secondary Sjogrens syndrome had a significantly positive rheumatoid factor, antinuclear antibody, anti Ro (SS-A) and anti La (SS-B) compared to rheumatoid patients without Sjogrens syndrome.
format Article
author Mustafa Al-Ahmad, Basma Ezzat
Mustafa, Nazih Shaban
Kashmola, Muhanad Ali Hamdon
author_facet Mustafa Al-Ahmad, Basma Ezzat
Mustafa, Nazih Shaban
Kashmola, Muhanad Ali Hamdon
author_sort Mustafa Al-Ahmad, Basma Ezzat
title Immunological Changes in Secondary Sjogran Syndrome (Comparative Study)
title_short Immunological Changes in Secondary Sjogran Syndrome (Comparative Study)
title_full Immunological Changes in Secondary Sjogran Syndrome (Comparative Study)
title_fullStr Immunological Changes in Secondary Sjogran Syndrome (Comparative Study)
title_full_unstemmed Immunological Changes in Secondary Sjogran Syndrome (Comparative Study)
title_sort immunological changes in secondary sjogran syndrome (comparative study)
publisher ELSEVIER
publishDate 2015
url http://irep.iium.edu.my/42214/
http://irep.iium.edu.my/42214/1/Immunological_Changes_in_Secondary_Sjogran_Syndrome.docx
http://irep.iium.edu.my/42214/5/Basma.pdf
first_indexed 2023-09-18T21:00:13Z
last_indexed 2023-09-18T21:00:13Z
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