Immunological Changes in Secondary Sjogran Syndrome (Comparative Study)
Objective This study was designed to evaluate the immunological changes and its existence for early diagnosis and proper management of disease. Study Design 56 patients with RA accompanied by sSS where included in this study and compared to 60 RA patients without sSS.Schirmers test, blood tests...
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iium-422142015-11-23T23:57:15Z http://irep.iium.edu.my/42214/ Immunological Changes in Secondary Sjogran Syndrome (Comparative Study) Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon R Medicine (General) Objective This study was designed to evaluate the immunological changes and its existence for early diagnosis and proper management of disease. Study Design 56 patients with RA accompanied by sSS where included in this study and compared to 60 RA patients without sSS.Schirmers test, blood tests and search for auto antibodies was done for all patients in both groups. Schirmers, blood tests and search for antinuclear antibody was done for all patients in both groups, with the measurement of salivary flow rate. Results Schirmers test was positive in all sSS and negative in all RA patients, whilst salivary flow rate was reduced in all sSS. Latex fixation test, ANA, Anti Ro and Anti La were reported significantly higher in sSS (p<0.01) Conclusions Secondary Sjogrens syndrome had a significantly positive rheumatoid factor, antinuclear antibody, anti Ro (SS-A) and anti La (SS-B) compared to rheumatoid patients without Sjogrens syndrome. ELSEVIER 2015-03 Article PeerReviewed application/pdf en http://irep.iium.edu.my/42214/1/Immunological_Changes_in_Secondary_Sjogran_Syndrome.docx application/pdf en http://irep.iium.edu.my/42214/5/Basma.pdf Mustafa Al-Ahmad, Basma Ezzat and Mustafa, Nazih Shaban and Kashmola, Muhanad Ali Hamdon (2015) Immunological Changes in Secondary Sjogran Syndrome (Comparative Study). Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 119 (3). e126. ISSN 2212-4411 |
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R Medicine (General) Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Immunological Changes in Secondary Sjogran Syndrome (Comparative Study) |
description |
Objective
This study was designed to evaluate the immunological changes and its existence for early diagnosis and proper management of disease.
Study Design
56 patients with RA accompanied by sSS where included in this study and compared to 60 RA patients without sSS.Schirmers test, blood tests and search for auto antibodies was done for all patients in both groups. Schirmers, blood tests and search for antinuclear antibody was done for all patients in both groups, with the measurement of salivary flow rate.
Results
Schirmers test was positive in all sSS and negative in all RA patients, whilst salivary flow rate was reduced in all sSS. Latex fixation test, ANA, Anti Ro and Anti La were reported significantly higher in sSS (p<0.01)
Conclusions
Secondary Sjogrens syndrome had a significantly positive rheumatoid factor, antinuclear antibody, anti Ro (SS-A) and anti La (SS-B) compared to rheumatoid patients without Sjogrens syndrome. |
format |
Article |
author |
Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon |
author_facet |
Mustafa Al-Ahmad, Basma Ezzat Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon |
author_sort |
Mustafa Al-Ahmad, Basma Ezzat |
title |
Immunological Changes in Secondary Sjogran Syndrome (Comparative Study) |
title_short |
Immunological Changes in Secondary Sjogran Syndrome (Comparative Study) |
title_full |
Immunological Changes in Secondary Sjogran Syndrome (Comparative Study) |
title_fullStr |
Immunological Changes in Secondary Sjogran Syndrome (Comparative Study) |
title_full_unstemmed |
Immunological Changes in Secondary Sjogran Syndrome (Comparative Study) |
title_sort |
immunological changes in secondary sjogran syndrome (comparative study) |
publisher |
ELSEVIER |
publishDate |
2015 |
url |
http://irep.iium.edu.my/42214/ http://irep.iium.edu.my/42214/1/Immunological_Changes_in_Secondary_Sjogran_Syndrome.docx http://irep.iium.edu.my/42214/5/Basma.pdf |
first_indexed |
2023-09-18T21:00:13Z |
last_indexed |
2023-09-18T21:00:13Z |
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1777410573736083456 |