Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel

Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel

Objective: To explore the in vitro antibacterial potential of the peel of Cucurbita moschata Duchesne (tropical pumpkin) (C. moschata) against human pathogenic bacteria. Methods: In the present study, dichloromethane (DCM), methanol (MEOH) and aqueous extracts of C. moschata peel were examined for i...

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Main Authors: Ahmed, Qamar Uddin, Helaluddin, Abul Bashar Mohammed, Khan Chowdhury, Ahmed Jalal
Format: Article
Language:English
Published: Coastal Life Medicine Media co. Limited 2014
Subjects:
QD Chemistry
RS Pharmacy and materia medica
Online Access:http://irep.iium.edu.my/41376/
http://irep.iium.edu.my/41376/
http://irep.iium.edu.my/41376/1/Pumpkin_peel_paper.pdf
id iium-41376
recordtype eprints
spelling iium-413762017-12-06T05:15:10Z http://irep.iium.edu.my/41376/ Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel Ahmed, Qamar Uddin Helaluddin, Abul Bashar Mohammed Khan Chowdhury, Ahmed Jalal QD Chemistry RS Pharmacy and materia medica Objective: To explore the in vitro antibacterial potential of the peel of Cucurbita moschata Duchesne (tropical pumpkin) (C. moschata) against human pathogenic bacteria. Methods: In the present study, dichloromethane (DCM), methanol (MEOH) and aqueous extracts of C. moschata peel were examined for in vitro antibacterial potency against eight bacterial strains i.e. Bacillus cereus, Burkholderia cepacia, Escherichia coli, Enterococcus faecalis, Staphyloccocus aureus, Pseudomonas aerugenosa, Vibrio alginolyticus, Vibrio parahaemolyticus using Kirby- Bauer disk diffusion susceptibility and broth micro-dilution methods. Results: DCM extract of pumpkin peel exhibited the maximum zone of inhibition against Staphyloccocus aureus (21 mm) whereas aqueous extract of pumpkin peel revealed the least zone aofg aininhsitb iPtisoenu daogmaionnsta sE sacehreurgicehnioas ac o(l1i9 ( 8m mmm). ).B MroEtOhH m eixctrroa-cdt igluavtieo nm amxeimthuomd szhoonwe eodf imnihnibimituiomn imnihniibmituomry bcaocntceernictirdaatilo cno fnocre tnhtera tDioCnMs ewxetrraec at lasgo adinestet rBmuinrkehdo tlod ekrinao wce pthaec inaa atut r6e. 2o5f malgl /emxLtr.a Tchtse. DCM and MEOH extracts exhibited bactericidal nature to all bacterial strains except for the Vibrio alginolyticus. The minimum bactericidal concentrations values exhibited bactericidal nature reaxntrgaicntgs forfo mC. 3m.1o2s cmhga/tma Lp etoe l 1r0e0v.0e0a lmedg /tmhaLt. tThhee D sCcMre eexntirnagc to pf oasnsteismsiecdr ogboioadl parnotpimeritcireosb oiaf l deiffffiecraecnyt compared to MEOH and aqueous extracts. Conclusions: Peel of C. moschata possesses antibacterial compounds and could be potential source for a new class of antibiotics. Coastal Life Medicine Media co. Limited 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/41376/1/Pumpkin_peel_paper.pdf Ahmed, Qamar Uddin and Helaluddin, Abul Bashar Mohammed and Khan Chowdhury, Ahmed Jalal (2014) Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel. Journal of Coastal Life Medicine, 2 (2). pp. 146-153. ISSN 2309-6152 (O), 2309-5288 (P) http://jclmm.com/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic QD Chemistry
RS Pharmacy and materia medica
spellingShingle QD Chemistry
RS Pharmacy and materia medica
Ahmed, Qamar Uddin
Helaluddin, Abul Bashar Mohammed
Khan Chowdhury, Ahmed Jalal
Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel
description Objective: To explore the in vitro antibacterial potential of the peel of Cucurbita moschata Duchesne (tropical pumpkin) (C. moschata) against human pathogenic bacteria. Methods: In the present study, dichloromethane (DCM), methanol (MEOH) and aqueous extracts of C. moschata peel were examined for in vitro antibacterial potency against eight bacterial strains i.e. Bacillus cereus, Burkholderia cepacia, Escherichia coli, Enterococcus faecalis, Staphyloccocus aureus, Pseudomonas aerugenosa, Vibrio alginolyticus, Vibrio parahaemolyticus using Kirby- Bauer disk diffusion susceptibility and broth micro-dilution methods. Results: DCM extract of pumpkin peel exhibited the maximum zone of inhibition against Staphyloccocus aureus (21 mm) whereas aqueous extract of pumpkin peel revealed the least zone aofg aininhsitb iPtisoenu daogmaionnsta sE sacehreurgicehnioas ac o(l1i9 ( 8m mmm). ).B MroEtOhH m eixctrroa-cdt igluavtieo nm amxeimthuomd szhoonwe eodf imnihnibimituiomn imnihniibmituomry bcaocntceernictirdaatilo cno fnocre tnhtera tDioCnMs ewxetrraec at lasgo adinestet rBmuinrkehdo tlod ekrinao wce pthaec inaa atut r6e. 2o5f malgl /emxLtr.a Tchtse. DCM and MEOH extracts exhibited bactericidal nature to all bacterial strains except for the Vibrio alginolyticus. The minimum bactericidal concentrations values exhibited bactericidal nature reaxntrgaicntgs forfo mC. 3m.1o2s cmhga/tma Lp etoe l 1r0e0v.0e0a lmedg /tmhaLt. tThhee D sCcMre eexntirnagc to pf oasnsteismsiecdr ogboioadl parnotpimeritcireosb oiaf l deiffffiecraecnyt compared to MEOH and aqueous extracts. Conclusions: Peel of C. moschata possesses antibacterial compounds and could be potential source for a new class of antibiotics.
format Article
author Ahmed, Qamar Uddin
Helaluddin, Abul Bashar Mohammed
Khan Chowdhury, Ahmed Jalal
author_facet Ahmed, Qamar Uddin
Helaluddin, Abul Bashar Mohammed
Khan Chowdhury, Ahmed Jalal
author_sort Ahmed, Qamar Uddin
title Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel
title_short Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel
title_full Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel
title_fullStr Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel
title_full_unstemmed Studies on bactericidal efficacy of pumpkin (Cucurbita moschata Duchesne) peel
title_sort studies on bactericidal efficacy of pumpkin (cucurbita moschata duchesne) peel
publisher Coastal Life Medicine Media co. Limited
publishDate 2014
url http://irep.iium.edu.my/41376/
http://irep.iium.edu.my/41376/
http://irep.iium.edu.my/41376/1/Pumpkin_peel_paper.pdf
first_indexed 2023-09-18T20:59:16Z
last_indexed 2023-09-18T20:59:16Z
_version_ 1777410513254219776

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