Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum

Cellulose is the most abundant biopolymer on earth. Enzymatic degradation of this biopolymer is a crucial step toward its conversion to bioethanol. However the current cellulosic enzymes are unable to withstand high temperature of industrial processes. In this work we use computer simulations to pre...

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Main Authors:	Noorbatcha, Ibrahim Ali, Ahmad, Abdul Aziz, Mohd. Salleh, Hamzah
Format:	Conference or Workshop Item
Language:	English English
Published:	2014
Subjects:	TP Chemical technology TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/41304/ http://irep.iium.edu.my/41304/ http://irep.iium.edu.my/41304/1/IIRIE_2014_EG_PosterID_485.pdf http://irep.iium.edu.my/41304/4/computational_prediction.pdf

id	iium-41304
recordtype	eprints
spelling	iium-413042018-06-19T08:01:22Z http://irep.iium.edu.my/41304/ Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum Noorbatcha, Ibrahim Ali Ahmad, Abdul Aziz Mohd. Salleh, Hamzah TP Chemical technology TP248.13 Biotechnology Cellulose is the most abundant biopolymer on earth. Enzymatic degradation of this biopolymer is a crucial step toward its conversion to bioethanol. However the current cellulosic enzymes are unable to withstand high temperature of industrial processes. In this work we use computer simulations to predict thermostable endoglucanase. The molecular dynamics simulation is a powerful tool that can be used to study the enzymes behaviour at high temperature. On the basis of computer simulations we have predicted a mutant endoglucanase with improved thermal stability properties. 2014-06-11 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/41304/1/IIRIE_2014_EG_PosterID_485.pdf application/pdf en http://irep.iium.edu.my/41304/4/computational_prediction.pdf Noorbatcha, Ibrahim Ali and Ahmad, Abdul Aziz and Mohd. Salleh, Hamzah (2014) Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum. In: International Research, Invention and Innovation Exhibition 2014 (IRIIE2014), 11th -13th June 2014, Cultural Activity Center (CAC), Internatioanal Islamic University Malaysia. (Unpublished) http://www.iium.edu.my/irie/14/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	TP Chemical technology TP248.13 Biotechnology
spellingShingle	TP Chemical technology TP248.13 Biotechnology Noorbatcha, Ibrahim Ali Ahmad, Abdul Aziz Mohd. Salleh, Hamzah Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
description	Cellulose is the most abundant biopolymer on earth. Enzymatic degradation of this biopolymer is a crucial step toward its conversion to bioethanol. However the current cellulosic enzymes are unable to withstand high temperature of industrial processes. In this work we use computer simulations to predict thermostable endoglucanase. The molecular dynamics simulation is a powerful tool that can be used to study the enzymes behaviour at high temperature. On the basis of computer simulations we have predicted a mutant endoglucanase with improved thermal stability properties.
format	Conference or Workshop Item
author	Noorbatcha, Ibrahim Ali Ahmad, Abdul Aziz Mohd. Salleh, Hamzah
author_facet	Noorbatcha, Ibrahim Ali Ahmad, Abdul Aziz Mohd. Salleh, Hamzah
author_sort	Noorbatcha, Ibrahim Ali
title	Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_short	Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_full	Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_fullStr	Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_full_unstemmed	Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum
title_sort	computational prediction and development of a thermostable endoglucanase i from fusarium oxysporum
publishDate	2014
url	http://irep.iium.edu.my/41304/ http://irep.iium.edu.my/41304/ http://irep.iium.edu.my/41304/1/IIRIE_2014_EG_PosterID_485.pdf http://irep.iium.edu.my/41304/4/computational_prediction.pdf
first_indexed	2023-09-18T20:59:10Z
last_indexed	2023-09-18T20:59:10Z
_version_	1777410507598200832

Computational prediction and development of a thermostable endoglucanase I from Fusarium oxysporum

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