Musculoskeletal melioodosis

Melioidosis that is caused by Burkholderia pseudomallei, is a significant public health problem in Southeast Asia and some other tropical countries. It involves many systems, especially the respiratory system. Melioidosis can mimic various common disease such as tuberculosis or tumor of the bones an...

Full description

Bibliographic Details
Main Authors: Che Ahmad, Aminudin, Zakaria@Mohamad, Zamzuri, Zulkifly, Ahmad Hafiz, Ab Rahman, Jamalludin, How, Soon Hin
Format: Conference or Workshop Item
Language:English
Published: 2007
Subjects:
Online Access:http://irep.iium.edu.my/41067/
http://irep.iium.edu.my/41067/
http://irep.iium.edu.my/41067/1/2.pdf
id iium-41067
recordtype eprints
spelling iium-410672016-03-10T07:04:45Z http://irep.iium.edu.my/41067/ Musculoskeletal melioodosis Che Ahmad, Aminudin Zakaria@Mohamad, Zamzuri Zulkifly, Ahmad Hafiz Ab Rahman, Jamalludin How, Soon Hin RA0421 Public health. Hygiene. Preventive Medicine RB Pathology RD701 Orthopedics Melioidosis that is caused by Burkholderia pseudomallei, is a significant public health problem in Southeast Asia and some other tropical countries. It involves many systems, especially the respiratory system. Melioidosis can mimic various common disease such as tuberculosis or tumor of the bones and joints. Mortality rates and relapse rate are high despite combination drug therapy. More than 300 cases of bacteriologically confirmed melioidosis have been detected in several hospital in Pahang, Malaysia. The purpose of this study is to determine the epidemiology, clinical features, bacteriology outcome and mortality of musculoskeletal form of melioidosis in Pahang, Malaysia. This is a study of twenty four patients, who had been diagnosed to have melioidosis involving musculoskeletal system carried out at three hospitals in Pahang, Malaysia from January 2000 to June 2006. Case records of conformed cases will be traced ad analyzed. The age, gender, ethic, nature of activity, clinical presentation, bacteriology, response to treatment and mortality obtained from case record. Twenty four patients (17 male and 7 female) reviewed. 92% has diabetes mellitus. Knee septic arthritis was the most common joint involved (42%, 11 cases), followed by ankle septic arthritis 15% (4 patients). Surgery was performed at least once in 88% (23 patients). Of all patients, 34% died within 6 month of diagnosis. High mortality and poor response to current treatment alarming us for such a dangerous organism and more studies need to be done for faster diagnosis and the best method to treat this disease. 2007 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/41067/1/2.pdf Che Ahmad, Aminudin and Zakaria@Mohamad, Zamzuri and Zulkifly, Ahmad Hafiz and Ab Rahman, Jamalludin and How, Soon Hin (2007) Musculoskeletal melioodosis. In: Fifth SICOT/SIROT Annual International Conference 2007, 29 August - 1 September 2007, Marrakech, Morocco. http://www.news.sicot.org
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RA0421 Public health. Hygiene. Preventive Medicine
RB Pathology
RD701 Orthopedics
spellingShingle RA0421 Public health. Hygiene. Preventive Medicine
RB Pathology
RD701 Orthopedics
Che Ahmad, Aminudin
Zakaria@Mohamad, Zamzuri
Zulkifly, Ahmad Hafiz
Ab Rahman, Jamalludin
How, Soon Hin
Musculoskeletal melioodosis
description Melioidosis that is caused by Burkholderia pseudomallei, is a significant public health problem in Southeast Asia and some other tropical countries. It involves many systems, especially the respiratory system. Melioidosis can mimic various common disease such as tuberculosis or tumor of the bones and joints. Mortality rates and relapse rate are high despite combination drug therapy. More than 300 cases of bacteriologically confirmed melioidosis have been detected in several hospital in Pahang, Malaysia. The purpose of this study is to determine the epidemiology, clinical features, bacteriology outcome and mortality of musculoskeletal form of melioidosis in Pahang, Malaysia. This is a study of twenty four patients, who had been diagnosed to have melioidosis involving musculoskeletal system carried out at three hospitals in Pahang, Malaysia from January 2000 to June 2006. Case records of conformed cases will be traced ad analyzed. The age, gender, ethic, nature of activity, clinical presentation, bacteriology, response to treatment and mortality obtained from case record. Twenty four patients (17 male and 7 female) reviewed. 92% has diabetes mellitus. Knee septic arthritis was the most common joint involved (42%, 11 cases), followed by ankle septic arthritis 15% (4 patients). Surgery was performed at least once in 88% (23 patients). Of all patients, 34% died within 6 month of diagnosis. High mortality and poor response to current treatment alarming us for such a dangerous organism and more studies need to be done for faster diagnosis and the best method to treat this disease.
format Conference or Workshop Item
author Che Ahmad, Aminudin
Zakaria@Mohamad, Zamzuri
Zulkifly, Ahmad Hafiz
Ab Rahman, Jamalludin
How, Soon Hin
author_facet Che Ahmad, Aminudin
Zakaria@Mohamad, Zamzuri
Zulkifly, Ahmad Hafiz
Ab Rahman, Jamalludin
How, Soon Hin
author_sort Che Ahmad, Aminudin
title Musculoskeletal melioodosis
title_short Musculoskeletal melioodosis
title_full Musculoskeletal melioodosis
title_fullStr Musculoskeletal melioodosis
title_full_unstemmed Musculoskeletal melioodosis
title_sort musculoskeletal melioodosis
publishDate 2007
url http://irep.iium.edu.my/41067/
http://irep.iium.edu.my/41067/
http://irep.iium.edu.my/41067/1/2.pdf
first_indexed 2023-09-18T20:58:50Z
last_indexed 2023-09-18T20:58:50Z
_version_ 1777410486125461504