In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens

Leucas cephalotes (Roth.) Spreng (family: Lamiaceae) is a rainy season weed widely distributed in tropical regions of Asia at elevation up to 1,700 m, medicinally employed for the treatment of skin diseases, fever, hepatic disorders, urinary complaints cough and cold. The traditional uses of this...

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Main Authors:	Khan, Abdul Viqar, Ahmed, Qamar Uddin, Khan, Athar Ali, Shukla, Indu
Format:	Article
Language:	English
Published:	Science Target 2014
Subjects:	QR Microbiology
Online Access:	http://irep.iium.edu.my/41001/ http://irep.iium.edu.my/41001/ http://irep.iium.edu.my/41001/1/In_Vitro_Antibacterial_Efficacy_of_Leucas_Cephalotes_%28Roth%29_Spreng..pdf

id	iium-41001
recordtype	eprints
spelling	iium-410012015-02-24T08:00:11Z http://irep.iium.edu.my/41001/ In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens Khan, Abdul Viqar Ahmed, Qamar Uddin Khan, Athar Ali Shukla, Indu QR Microbiology Leucas cephalotes (Roth.) Spreng (family: Lamiaceae) is a rainy season weed widely distributed in tropical regions of Asia at elevation up to 1,700 m, medicinally employed for the treatment of skin diseases, fever, hepatic disorders, urinary complaints cough and cold. The traditional uses of this plant strongly suggest its possible antibacterial properties, but its efficacy has not been examined in broad scenes, in present communication, its antibacterial efficacy has been explored. Polar and non-polar extracts (ethyl acetate, methanol, aqueous, benzene, and petroleum ether) at five different concentrations (0.5, 1, 2, 5, and 10 mg/mL) were evaluated for their antibacterial efficacy against seven G+ and eleven G– hospital isolated bacteria. Disc diffusion method was followed to determine antibacterial activity. Phytochemical analysis of plant revealed presence of tannins, glycosides, saponins, steroids, phenolic compounds and flavonoids as secondary metabolites. Maximum antibacterial activity was demonstrated by ethyl acetate and methanol extracts at a minimum concentration (0.5 mg/mL/disc). Extracts were effective on both types of test pathogens. From the present findings, it may be concluded that the plant could be formulated in broad spectrum antibiotic and confirms the traditional uses in pathogenic diseases. Keywords: Leucas cephalotes (Roth) Spreng, Antibacterial efficacy, crude extracts, traditional uses Science Target 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/41001/1/In_Vitro_Antibacterial_Efficacy_of_Leucas_Cephalotes_%28Roth%29_Spreng..pdf Khan, Abdul Viqar and Ahmed, Qamar Uddin and Khan, Athar Ali and Shukla, Indu (2014) In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens. International Journal of Agricultural and Food Research, 3 (3). pp. 1-9. ISSN 1929-0969 https://www.sciencetarget.com/Journal/index.php/IJAFR
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QR Microbiology
spellingShingle	QR Microbiology Khan, Abdul Viqar Ahmed, Qamar Uddin Khan, Athar Ali Shukla, Indu In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens
description	Leucas cephalotes (Roth.) Spreng (family: Lamiaceae) is a rainy season weed widely distributed in tropical regions of Asia at elevation up to 1,700 m, medicinally employed for the treatment of skin diseases, fever, hepatic disorders, urinary complaints cough and cold. The traditional uses of this plant strongly suggest its possible antibacterial properties, but its efficacy has not been examined in broad scenes, in present communication, its antibacterial efficacy has been explored. Polar and non-polar extracts (ethyl acetate, methanol, aqueous, benzene, and petroleum ether) at five different concentrations (0.5, 1, 2, 5, and 10 mg/mL) were evaluated for their antibacterial efficacy against seven G+ and eleven G– hospital isolated bacteria. Disc diffusion method was followed to determine antibacterial activity. Phytochemical analysis of plant revealed presence of tannins, glycosides, saponins, steroids, phenolic compounds and flavonoids as secondary metabolites. Maximum antibacterial activity was demonstrated by ethyl acetate and methanol extracts at a minimum concentration (0.5 mg/mL/disc). Extracts were effective on both types of test pathogens. From the present findings, it may be concluded that the plant could be formulated in broad spectrum antibiotic and confirms the traditional uses in pathogenic diseases. Keywords: Leucas cephalotes (Roth) Spreng, Antibacterial efficacy, crude extracts, traditional uses
format	Article
author	Khan, Abdul Viqar Ahmed, Qamar Uddin Khan, Athar Ali Shukla, Indu
author_facet	Khan, Abdul Viqar Ahmed, Qamar Uddin Khan, Athar Ali Shukla, Indu
author_sort	Khan, Abdul Viqar
title	In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens
title_short	In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens
title_full	In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens
title_fullStr	In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens
title_full_unstemmed	In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens
title_sort	in vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens
publisher	Science Target
publishDate	2014
url	http://irep.iium.edu.my/41001/ http://irep.iium.edu.my/41001/ http://irep.iium.edu.my/41001/1/In_Vitro_Antibacterial_Efficacy_of_Leucas_Cephalotes_%28Roth%29_Spreng..pdf
first_indexed	2023-09-18T20:58:44Z
last_indexed	2023-09-18T20:58:44Z
_version_	1777410479878045696

In vitro antibacterial efficacy of leucas cephalotes (roth) spreng. (lamiaceae) against some gram positive and gram negative human pathogens

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