Biochemical effects of Nigella sativa seeds in diabetic rats

Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydropero...

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Main Author: Ahmed, Qamar Uddin
Format: Article
Language:English
Published: National Institute of Science Communication and Information Resources (NISCAIR), India. 2006
Subjects:
Online Access:http://irep.iium.edu.my/40985/
http://irep.iium.edu.my/40985/
http://irep.iium.edu.my/40985/1/Biochemical_effects_of_Nigella_sativa_seeds_in_diabetic_rats..pdf
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spelling iium-409852015-03-04T02:27:49Z http://irep.iium.edu.my/40985/ Biochemical effects of Nigella sativa seeds in diabetic rats Ahmed, Qamar Uddin Q Science (General) Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydroperoxides) and antioxidant enzymes like catalase, superoxide dismutase, reduced glutathione and glutathione peroxidase in liver and kidney. The results confirm the antidiabetic activity of N. sativa seeds extract and suggest that because of its antioxidant effects its administration may be useful in controlling the diabetic complications in experimental diabetic rats. National Institute of Science Communication and Information Resources (NISCAIR), India. 2006-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/40985/1/Biochemical_effects_of_Nigella_sativa_seeds_in_diabetic_rats..pdf Ahmed, Qamar Uddin (2006) Biochemical effects of Nigella sativa seeds in diabetic rats. Indian Journal of Experimental Biology , 44 (9). pp. 745-748. ISSN 0975-1009 http://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb2k6/ijep_sept06.asp
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic Q Science (General)
spellingShingle Q Science (General)
Ahmed, Qamar Uddin
Biochemical effects of Nigella sativa seeds in diabetic rats
description Oral administration of ethanol extract of N. sativa seeds (300 mg/kg body weight/day) to streptozotocin induced diabetic rats for 30 days significantly reduced the elevated levels of blood glucose, lipids, plasma insulin and improved altered levels of lipid peroxidation products (TBARS and hydroperoxides) and antioxidant enzymes like catalase, superoxide dismutase, reduced glutathione and glutathione peroxidase in liver and kidney. The results confirm the antidiabetic activity of N. sativa seeds extract and suggest that because of its antioxidant effects its administration may be useful in controlling the diabetic complications in experimental diabetic rats.
format Article
author Ahmed, Qamar Uddin
author_facet Ahmed, Qamar Uddin
author_sort Ahmed, Qamar Uddin
title Biochemical effects of Nigella sativa seeds in diabetic rats
title_short Biochemical effects of Nigella sativa seeds in diabetic rats
title_full Biochemical effects of Nigella sativa seeds in diabetic rats
title_fullStr Biochemical effects of Nigella sativa seeds in diabetic rats
title_full_unstemmed Biochemical effects of Nigella sativa seeds in diabetic rats
title_sort biochemical effects of nigella sativa seeds in diabetic rats
publisher National Institute of Science Communication and Information Resources (NISCAIR), India.
publishDate 2006
url http://irep.iium.edu.my/40985/
http://irep.iium.edu.my/40985/
http://irep.iium.edu.my/40985/1/Biochemical_effects_of_Nigella_sativa_seeds_in_diabetic_rats..pdf
first_indexed 2023-09-18T20:58:43Z
last_indexed 2023-09-18T20:58:43Z
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