Zone specific fractal dimension of retinal images as predictor of stroke incidence

Fractal dimensions (FDs) are frequently used for summarizing the complexity of retinal vascular. However, previous techniques on this topic were not zone specific. A new methodology to measure FD of a specific zone in retinal images has been developed and tested as a marker for stroke prediction. Hi...

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Main Authors: Aliahmad, Behzad, Kumar, Dinesh Kant, Hao, Hao, Unnikrishnan, Premith, Che Azemin, Mohd Zulfaezal, Kawasaki, Ryo, Mitchell, Paul
Format: Article
Language:English
English
Published: Hindawi Publishing Corporation 2014
Subjects:
Online Access:http://irep.iium.edu.my/40328/
http://irep.iium.edu.my/40328/
http://irep.iium.edu.my/40328/
http://irep.iium.edu.my/40328/3/zone_specific.pdf
http://irep.iium.edu.my/40328/6/40328-Zone%20specific%20fractal%20dimension%20of%20retinal%20images%20as%20predictor%20of%20stroke%20incidence.pdf
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recordtype eprints
spelling iium-403282017-08-24T06:39:52Z http://irep.iium.edu.my/40328/ Zone specific fractal dimension of retinal images as predictor of stroke incidence Aliahmad, Behzad Kumar, Dinesh Kant Hao, Hao Unnikrishnan, Premith Che Azemin, Mohd Zulfaezal Kawasaki, Ryo Mitchell, Paul RE Ophthalmology TA164 Bioengineering Fractal dimensions (FDs) are frequently used for summarizing the complexity of retinal vascular. However, previous techniques on this topic were not zone specific. A new methodology to measure FD of a specific zone in retinal images has been developed and tested as a marker for stroke prediction. Higuchi's fractal dimension was measured in circumferential direction (FDC) with respect to optic disk (OD), in three concentric regions between OD boundary and 1.5 OD diameter from its margin. The significance of its association with future episode of stroke event was tested using the Blue Mountain Eye Study (BMES) database and compared against spectrum fractal dimension (SFD) and box-counting (BC) dimension. Kruskal-Wallis analysis revealed FDC as a better predictor of stroke (H=5.80, P=0.016, α=0.05) compared with SFD (H=0.51, P=0.475, α=0.05) and BC (H=0.41, P=0.520, α=0.05) with overall lower median value for the cases compared to the control group. This work has shown that there is a significant association between zone specific FDC of eye fundus images with future episode of stroke while this difference is not significant when other FD methods are employed. Hindawi Publishing Corporation 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/40328/3/zone_specific.pdf application/pdf en http://irep.iium.edu.my/40328/6/40328-Zone%20specific%20fractal%20dimension%20of%20retinal%20images%20as%20predictor%20of%20stroke%20incidence.pdf Aliahmad, Behzad and Kumar, Dinesh Kant and Hao, Hao and Unnikrishnan, Premith and Che Azemin, Mohd Zulfaezal and Kawasaki, Ryo and Mitchell, Paul (2014) Zone specific fractal dimension of retinal images as predictor of stroke incidence. The Scientific World Journal, 2014. pp. 1-7. ISSN 2356-6140 http://dx.doi.org/10.1155/2014/467462 doi:10.1155/2014/467462
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic RE Ophthalmology
TA164 Bioengineering
spellingShingle RE Ophthalmology
TA164 Bioengineering
Aliahmad, Behzad
Kumar, Dinesh Kant
Hao, Hao
Unnikrishnan, Premith
Che Azemin, Mohd Zulfaezal
Kawasaki, Ryo
Mitchell, Paul
Zone specific fractal dimension of retinal images as predictor of stroke incidence
description Fractal dimensions (FDs) are frequently used for summarizing the complexity of retinal vascular. However, previous techniques on this topic were not zone specific. A new methodology to measure FD of a specific zone in retinal images has been developed and tested as a marker for stroke prediction. Higuchi's fractal dimension was measured in circumferential direction (FDC) with respect to optic disk (OD), in three concentric regions between OD boundary and 1.5 OD diameter from its margin. The significance of its association with future episode of stroke event was tested using the Blue Mountain Eye Study (BMES) database and compared against spectrum fractal dimension (SFD) and box-counting (BC) dimension. Kruskal-Wallis analysis revealed FDC as a better predictor of stroke (H=5.80, P=0.016, α=0.05) compared with SFD (H=0.51, P=0.475, α=0.05) and BC (H=0.41, P=0.520, α=0.05) with overall lower median value for the cases compared to the control group. This work has shown that there is a significant association between zone specific FDC of eye fundus images with future episode of stroke while this difference is not significant when other FD methods are employed.
format Article
author Aliahmad, Behzad
Kumar, Dinesh Kant
Hao, Hao
Unnikrishnan, Premith
Che Azemin, Mohd Zulfaezal
Kawasaki, Ryo
Mitchell, Paul
author_facet Aliahmad, Behzad
Kumar, Dinesh Kant
Hao, Hao
Unnikrishnan, Premith
Che Azemin, Mohd Zulfaezal
Kawasaki, Ryo
Mitchell, Paul
author_sort Aliahmad, Behzad
title Zone specific fractal dimension of retinal images as predictor of stroke incidence
title_short Zone specific fractal dimension of retinal images as predictor of stroke incidence
title_full Zone specific fractal dimension of retinal images as predictor of stroke incidence
title_fullStr Zone specific fractal dimension of retinal images as predictor of stroke incidence
title_full_unstemmed Zone specific fractal dimension of retinal images as predictor of stroke incidence
title_sort zone specific fractal dimension of retinal images as predictor of stroke incidence
publisher Hindawi Publishing Corporation
publishDate 2014
url http://irep.iium.edu.my/40328/
http://irep.iium.edu.my/40328/
http://irep.iium.edu.my/40328/
http://irep.iium.edu.my/40328/3/zone_specific.pdf
http://irep.iium.edu.my/40328/6/40328-Zone%20specific%20fractal%20dimension%20of%20retinal%20images%20as%20predictor%20of%20stroke%20incidence.pdf
first_indexed 2023-09-18T20:57:50Z
last_indexed 2023-09-18T20:57:50Z
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