Effects of operating conditions in spray drying of recombinant bromelain
The aim of the present study is to investigate the effect of operating parameter of a Buchi B290 mini spray dryer towards specific activity of recBromelain. Using Response Surface Methodology (RSM), face centred central composite design (FCCCD) was tabulated for optimization. Optimization process...
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| Format: | Article |
| Language: | English |
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AENSI
2014
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| Online Access: | http://irep.iium.edu.my/39951/ http://irep.iium.edu.my/39951/1/JASA_Dec_14.pdf |
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iium-39951 |
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eprints |
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iium-399512018-05-24T01:33:55Z http://irep.iium.edu.my/39951/ Effects of operating conditions in spray drying of recombinant bromelain Amid, Azura Othman, Muhd. Ezza Faiez Jamaluddin, Mohd Jamil Aizat TP248.13 Biotechnology The aim of the present study is to investigate the effect of operating parameter of a Buchi B290 mini spray dryer towards specific activity of recBromelain. Using Response Surface Methodology (RSM), face centred central composite design (FCCCD) was tabulated for optimization. Optimization process was conducted by varying the inlet air temperature (°C), gas flow height (mm) and pump settings (%) of the laboratory Buchi B290 Mini Spray Dryer to obtained optimal spray drying operating processes recovering high recBromelain specific activity as response. Results showed that the optimized process parameter having 126 °C air inlet temperature, 42 mm gas flow height and 12 % feed pump setting resulted in 0.119 ± 0.003 U/mgprotein of spray dried recBromelain with R2 of 90.12% thus this model was found to be significance and reliable. AENSI 2014-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/39951/1/JASA_Dec_14.pdf Amid, Azura and Othman, Muhd. Ezza Faiez and Jamaluddin, Mohd Jamil Aizat (2014) Effects of operating conditions in spray drying of recombinant bromelain. Journal of Applied Science and Agriculture, 9 (20). pp. 37-43. ISSN 1816-9112 |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English |
| topic |
TP248.13 Biotechnology |
| spellingShingle |
TP248.13 Biotechnology Amid, Azura Othman, Muhd. Ezza Faiez Jamaluddin, Mohd Jamil Aizat Effects of operating conditions in spray drying of recombinant bromelain |
| description |
The aim of the present study is to investigate the effect of operating
parameter of a Buchi B290 mini spray dryer towards specific activity of recBromelain.
Using Response Surface Methodology (RSM), face centred central composite design
(FCCCD) was tabulated for optimization. Optimization process was conducted by
varying the inlet air temperature (°C), gas flow height (mm) and pump settings (%) of
the laboratory Buchi B290 Mini Spray Dryer to obtained optimal spray drying
operating processes recovering high recBromelain specific activity as response. Results
showed that the optimized process parameter having 126 °C air inlet temperature, 42
mm gas flow height and 12 % feed pump setting resulted in 0.119 ± 0.003 U/mgprotein
of spray dried recBromelain with R2 of 90.12% thus this model was found to be
significance and reliable. |
| format |
Article |
| author |
Amid, Azura Othman, Muhd. Ezza Faiez Jamaluddin, Mohd Jamil Aizat |
| author_facet |
Amid, Azura Othman, Muhd. Ezza Faiez Jamaluddin, Mohd Jamil Aizat |
| author_sort |
Amid, Azura |
| title |
Effects of operating conditions in spray drying of recombinant bromelain |
| title_short |
Effects of operating conditions in spray drying of recombinant bromelain |
| title_full |
Effects of operating conditions in spray drying of recombinant bromelain |
| title_fullStr |
Effects of operating conditions in spray drying of recombinant bromelain |
| title_full_unstemmed |
Effects of operating conditions in spray drying of recombinant bromelain |
| title_sort |
effects of operating conditions in spray drying of recombinant bromelain |
| publisher |
AENSI |
| publishDate |
2014 |
| url |
http://irep.iium.edu.my/39951/ http://irep.iium.edu.my/39951/1/JASA_Dec_14.pdf |
| first_indexed |
2023-09-18T20:57:21Z |
| last_indexed |
2023-09-18T20:57:21Z |
| _version_ |
1777410392979406848 |