Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria

Background: Bacopa monnieri (Linn) Pennell (Scrophulariaceae) is widely distributed in tropical regions of Asia, and used in the treatment of cough or as an antiseptic. The traditional use of this plant suggests its possible antibacterial properties, but its efficacy has not been examined yet. Ob...

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Main Authors:	Khan, Abdul Viqar, Ahmed, Qamar Uddin, Shukla, Indu, Khan, Athar Ali
Format:	Article
Language:	English
Published:	Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. 2010
Subjects:	QD Chemistry RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/3990/ http://irep.iium.edu.my/3990/ http://irep.iium.edu.my/3990/ http://irep.iium.edu.my/3990/1/Antibacterial_efficacy_of_Bacopa_monnieri_leaf_extracts.pdf

id	iium-3990
recordtype	eprints
spelling	iium-39902012-01-27T02:07:22Z http://irep.iium.edu.my/3990/ Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria Khan, Abdul Viqar Ahmed, Qamar Uddin Shukla, Indu Khan, Athar Ali QD Chemistry RM Therapeutics. Pharmacology Background: Bacopa monnieri (Linn) Pennell (Scrophulariaceae) is widely distributed in tropical regions of Asia, and used in the treatment of cough or as an antiseptic. The traditional use of this plant suggests its possible antibacterial properties, but its efficacy has not been examined yet. Objective: Evaluate the antibacterial efficacy against pathogenic bacteria using the disk diffusion method. Materials and methods: Five different concentrations (500 μg, 1, 2, 5, 10, and 15 mg/mL) of crude leaf extracts of Bacopa monnieri (L.) Pennell were tested for antibacterial efficacy against seven Gram-positive and 11 Gramnegative bacteria. The sensitivity of plant fractions was tested using the disk diffusion method. Results: Maximum activity was revealed by ethyl acetate and methanol extracts, followed by aqueous, benzene, and petrol extracts. Phyto-chemical analysis of the plant leaf showed the presence of alkaloids, flavonoids, and saponins. Conclusion: This plant may be effective for treatment of different pathogenic diseases. Keywords: Antibacterial efficacy, Bacopa monnieri (L.) Pennell, crude extracts, traditional use Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. 2010-08-04 Article PeerReviewed application/pdf en cc_by_nc http://irep.iium.edu.my/3990/1/Antibacterial_efficacy_of_Bacopa_monnieri_leaf_extracts.pdf Khan, Abdul Viqar and Ahmed, Qamar Uddin and Shukla, Indu and Khan, Athar Ali (2010) Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria. Asian Biomedicine, 4 (4). 651-655.. ISSN 1905-7415 http://thailand.digitaljournals.org/index.php/ABM/index http://abm.digitaljournals.org/index.php/abm/article/viewFile/563/417
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry RM Therapeutics. Pharmacology
spellingShingle	QD Chemistry RM Therapeutics. Pharmacology Khan, Abdul Viqar Ahmed, Qamar Uddin Shukla, Indu Khan, Athar Ali Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria
description	Background: Bacopa monnieri (Linn) Pennell (Scrophulariaceae) is widely distributed in tropical regions of Asia, and used in the treatment of cough or as an antiseptic. The traditional use of this plant suggests its possible antibacterial properties, but its efficacy has not been examined yet. Objective: Evaluate the antibacterial efficacy against pathogenic bacteria using the disk diffusion method. Materials and methods: Five different concentrations (500 μg, 1, 2, 5, 10, and 15 mg/mL) of crude leaf extracts of Bacopa monnieri (L.) Pennell were tested for antibacterial efficacy against seven Gram-positive and 11 Gramnegative bacteria. The sensitivity of plant fractions was tested using the disk diffusion method. Results: Maximum activity was revealed by ethyl acetate and methanol extracts, followed by aqueous, benzene, and petrol extracts. Phyto-chemical analysis of the plant leaf showed the presence of alkaloids, flavonoids, and saponins. Conclusion: This plant may be effective for treatment of different pathogenic diseases. Keywords: Antibacterial efficacy, Bacopa monnieri (L.) Pennell, crude extracts, traditional use
format	Article
author	Khan, Abdul Viqar Ahmed, Qamar Uddin Shukla, Indu Khan, Athar Ali
author_facet	Khan, Abdul Viqar Ahmed, Qamar Uddin Shukla, Indu Khan, Athar Ali
author_sort	Khan, Abdul Viqar
title	Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria
title_short	Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria
title_full	Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria
title_fullStr	Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria
title_full_unstemmed	Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria
title_sort	antibacterial efficacy of bacopa monnieri leaf extracts against pathogenic bacteria
publisher	Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
publishDate	2010
url	http://irep.iium.edu.my/3990/ http://irep.iium.edu.my/3990/ http://irep.iium.edu.my/3990/ http://irep.iium.edu.my/3990/1/Antibacterial_efficacy_of_Bacopa_monnieri_leaf_extracts.pdf
first_indexed	2023-09-18T20:12:01Z
last_indexed	2023-09-18T20:12:01Z
_version_	1777407540671283200

Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria

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